| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Occlusion | D054059 | 4 associated lipids |
14r,15s-epetre
14r,15s-epetre is a lipid of Fatty Acyls (FA) class. 14r,15s-epetre is associated with abnormalities such as Heart failure, Chronic Obstructive Airway Disease, Pneumonia and Fatty Liver. The involved functions are known as chromophore, Stereochemistry, Cell Respiration, cell transformation and oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. 14r,15s-epetre often locates in Lambda, Cardiovascular system, Blood, Body tissue and Protoplasm. The associated genes with 14r,15s-epetre are CCL2 gene, Cytokine Gene, CYP2C18 gene, CYP2C19 gene and TEK gene. The related lipids are Palmitates.
Cross Reference
Introduction
To understand associated biological information of 14r,15s-epetre, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 14r,15s-epetre?
14r,15s-epetre is suspected in Heart failure, Chronic Obstructive Airway Disease, Pneumonia, Fatty Liver and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Am. J. Physiol. Endocrinol. Metab. (1)
- Am. J. Physiol. Lung Cell Mol. Physiol. (1)
- Prostaglandins Other Lipid Mediat. (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 14r,15s-epetre
PubChem Associated disorders and diseases
What pathways are associated with 14r,15s-epetre
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 14r,15s-epetre?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Am. J. Physiol. Lung Cell Mol. Physiol. (2)
- Am. J. Physiol. Endocrinol. Metab. (1)
- Hypertension (1)
- Others (2)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 14r,15s-epetre?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 14r,15s-epetre?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 14r,15s-epetre?
Related references are published most in these journals:
- Am. J. Physiol. Endocrinol. Metab. (1)
- Am. J. Physiol. Lung Cell Mol. Physiol. (1)
- Hypertension (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 14r,15s-epetre?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 14r,15s-epetre
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
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| Kandhi S et al. | EETs Elicit Direct Increases in Pulmonary Arterial Pressure in Mice. | 2016 | Am. J. Hypertens. | pmid:26304959 |
| Sporková A et al. | Interlobular Arteries From 2-Kidney, 1-Clip Goldblatt Hypertensive Rats' Exhibit-Impaired Vasodilator Response to Epoxyeicosatrienoic Acids. | 2016 | Am. J. Med. Sci. | pmid:27140711 |
| Pfister SL et al. | Enhanced synthesis of epoxyeicosatrienoic acids by cholesterol-fed rabbit aorta. | 1991 | Am. J. Physiol. | pmid:1887929 |
| Leffler CW and Fedinec AL | Newborn piglet cerebral microvascular responses to epoxyeicosatrienoic acids. | 1997 | Am. J. Physiol. | pmid:9249508 |
| Ma YH et al. | Altered renal P-450 metabolism of arachidonic acid in Dahl salt-sensitive rats. | 1994 | Am. J. Physiol. | pmid:8067471 |
| Snyder GD et al. | Effect of epoxyeicosatrienoic acids on growth hormone release from somatotrophs. | 1989 | Am. J. Physiol. | pmid:2563927 |
| Imig JD et al. | Cytochrome P-450 inhibitors alter afferent arteriolar responses to elevations in pressure. | 1994 | Am. J. Physiol. | pmid:8203587 |
| Fang X et al. | 14,15-Epoxyeicosatrienoic acid inhibits prostaglandin E2 production in vascular smooth muscle cells. | 1998 | Am. J. Physiol. | pmid:9843811 |
| Moffat MP et al. | Effects of epoxyeicosatrienoic acids on isolated hearts and ventricular myocytes. | 1993 | Am. J. Physiol. | pmid:8476093 |
| Rosolowsky M and Campbell WB | Role of PGI2 and epoxyeicosatrienoic acids in relaxation of bovine coronary arteries to arachidonic acid. | 1993 | Am. J. Physiol. | pmid:8447448 |
| Schlondorff D et al. | Epoxygenase metabolites of arachidonic acid inhibit vasopressin response in toad bladder. | 1987 | Am. J. Physiol. | pmid:2820243 |
| Weintraub NL et al. | Epoxide hydrolases regulate epoxyeicosatrienoic acid incorporation into coronary endothelial phospholipids. | 1999 | Am. J. Physiol. | pmid:10564166 |
| Zou AP et al. | Stereospecific effects of epoxyeicosatrienoic acids on renal vascular tone and K(+)-channel activity. | 1996 | Am. J. Physiol. | pmid:8928844 |
| Ellis EF et al. | Dilation of cerebral arterioles by cytochrome P-450 metabolites of arachidonic acid. | 1990 | Am. J. Physiol. | pmid:2121049 |
| Henrich WL et al. | Inhibition of renin release by 14,15-epoxyeicosatrienoic acid in renal cortical slices. | 1990 | Am. J. Physiol. | pmid:2154933 |
| Chadderdon SM et al. | Activity restriction, impaired capillary function, and the development of insulin resistance in lean primates. | 2012 | Am. J. Physiol. Endocrinol. Metab. | pmid:22739105 |
| Chen G et al. | CYP2J2 overexpression attenuates nonalcoholic fatty liver disease induced by high-fat diet in mice. | 2015 | Am. J. Physiol. Endocrinol. Metab. | pmid:25389366 |
| Sacerdoti D et al. | Rat mesenteric arterial dilator response to 11,12-epoxyeicosatrienoic acid is mediated by activating heme oxygenase. | 2006 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16798831 |
| Motoki A et al. | Soluble epoxide hydrolase inhibition and gene deletion are protective against myocardial ischemia-reperfusion injury in vivo. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18835921 |
| Miller AW et al. | Epoxyeicosatrienoic acid-induced relaxation is impaired in insulin resistance. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11557540 |
| Zhang Y et al. | EET homologs potently dilate coronary microvessels and activate BK(Ca) channels. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11356595 |
| Rastaldo R et al. | Cytochrome P-450 metabolite of arachidonic acid mediates bradykinin-induced negative inotropic effect. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11356641 |
| Campbell WB et al. | 14,15-Dihydroxyeicosatrienoic acid relaxes bovine coronary arteries by activation of K(Ca) channels. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11959628 |
| Snyder GD et al. | Evidence for a membrane site of action for 14,15-EET on expression of aromatase in vascular smooth muscle. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12384472 |
| Falck JR et al. | Comparison of vasodilatory properties of 14,15-EET analogs: structural requirements for dilation. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12388250 |
| Medhora M et al. | Epoxygenase-driven angiogenesis in human lung microvascular endothelial cells. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12388259 |
| Fang X et al. | Human coronary endothelial cells convert 14,15-EET to a biologically active chain-shortened epoxide. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12388281 |
| Gross GJ et al. | Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18441205 |