MeSH term | MeSH ID | Detail |
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Coronary Occlusion | D054059 | 4 associated lipids |
14r,15s-epetre is a lipid of Fatty Acyls (FA) class. 14r,15s-epetre is associated with abnormalities such as Heart failure, Chronic Obstructive Airway Disease, Pneumonia and Fatty Liver. The involved functions are known as chromophore, Stereochemistry, Cell Respiration, cell transformation and oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. 14r,15s-epetre often locates in Lambda, Cardiovascular system, Blood, Body tissue and Protoplasm. The associated genes with 14r,15s-epetre are CCL2 gene, Cytokine Gene, CYP2C18 gene, CYP2C19 gene and TEK gene. The related lipids are Palmitates.
To understand associated biological information of 14r,15s-epetre, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
14r,15s-epetre is suspected in Heart failure, Chronic Obstructive Airway Disease, Pneumonia, Fatty Liver and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 14r,15s-epetre
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Miller AW et al. | Epoxyeicosatrienoic acid-induced relaxation is impaired in insulin resistance. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11557540 |
Fisslthaler B et al. | Cyclic stretch enhances the expression and activity of coronary endothelium-derived hyperpolarizing factor synthase. | 2001 | Hypertension | pmid:11751730 |
Nithipatikom K et al. | Determination of cytochrome P450 metabolites of arachidonic acid in coronary venous plasma during ischemia and reperfusion in dogs. | 2001 | Anal. Biochem. | pmid:11319825 |
Fang X et al. | Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells. Implications for the vascular effects of soluble epoxide hydrolase inhibition. | 2001 | J. Biol. Chem. | pmid:11278979 |
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Benoit C et al. | EETs relax airway smooth muscle via an EpDHF effect: BK(Ca) channel activation and hyperpolarization. | 2001 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:11290521 |
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Nithipatikom K et al. | Determination of EETs using microbore liquid chromatography with fluorescence detection. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:10924087 |
Zhu D et al. | Epoxyeicosatrienoic acids constrict isolated pressurized rabbit pulmonary arteries. | 2000 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:10666118 |
Wu SN et al. | Actions of epoxyeicosatrienoic acid on large-conductance Ca(2+)-activated K(+) channels in pituitary GH(3) cells. | 2000 | Biochem. Pharmacol. | pmid:10825470 |
Yu Z et al. | Increased CYP2J expression and epoxyeicosatrienoic acid formation in spontaneously hypertensive rat kidney. | 2000 | Mol. Pharmacol. | pmid:10779386 |
Chen JK et al. | Overexpression of C-terminal Src kinase blocks 14, 15-epoxyeicosatrienoic acid-induced tyrosine phosphorylation and mitogenesis. | 2000 | J. Biol. Chem. | pmid:10788500 |
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Yu Z et al. | Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. | 2000 | Circ. Res. | pmid:11090543 |
Wong PY et al. | Mechanism and signal transduction of 14 (R), 15 (S)-epoxyeicosatrienoic acid (14,15-EET) binding in guinea pig monocytes. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:11060896 |
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Rzigalinski BA et al. | Calcium influx factor, further evidence it is 5, 6-epoxyeicosatrienoic acid. | 1999 | J. Biol. Chem. | pmid:9867827 |
Lee HC et al. | Effects of epoxyeicosatrienoic acids on the cardiac sodium channels in isolated rat ventricular myocytes. | 1999 | J. Physiol. (Lond.) | pmid:10432346 |
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Silverstein DM et al. | Multiple arachidonic acid metabolites inhibit sodium-dependent phosphate transport in OK cells. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10582656 |
Fang X et al. | Epoxyeicosatrienoic acids increase intracellular calcium concentration in vascular smooth muscle cells. | 1999 | Hypertension | pmid:10601125 |
Weintraub NL et al. | Epoxide hydrolases regulate epoxyeicosatrienoic acid incorporation into coronary endothelial phospholipids. | 1999 | Am. J. Physiol. | pmid:10564166 |
Huang S et al. | Interleukin-1 stimulates Jun N-terminal/stress-activated protein kinase by an arachidonate-dependent mechanism in mesangial cells. | 1999 | Kidney Int. | pmid:10231436 |
Chen JK et al. | Transfection of an active cytochrome P450 arachidonic acid epoxygenase indicates that 14,15-epoxyeicosatrienoic acid functions as an intracellular second messenger in response to epidermal growth factor. | 1999 | J. Biol. Chem. | pmid:9988714 |
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Fang X et al. | 14,15-Epoxyeicosatrienoic acid inhibits prostaglandin E2 production in vascular smooth muscle cells. | 1998 | Am. J. Physiol. | pmid:9843811 |
Peri KG et al. | Stimulation of prostaglandin G/H synthase-2 expression by arachidonic acid monoxygenase product, 14,15-epoxyeicosatrienoic acid. | 1997 | FEBS Lett. | pmid:9373167 |
Weintraub NL et al. | Potentiation of endothelium-dependent relaxation by epoxyeicosatrienoic acids. | 1997 | Circ. Res. | pmid:9242187 |
Wong PY et al. | Post-receptor signal transduction and regulation of 14(R),15(S)-epoxyeicosatrienoic acid (14,15-EET) binding in U-937 cells. | 1997 | J Lipid Mediat Cell Signal | pmid:9246605 |
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