MeSH term | MeSH ID | Detail |
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Coronary Occlusion | D054059 | 4 associated lipids |
14r,15s-epetre is a lipid of Fatty Acyls (FA) class. 14r,15s-epetre is associated with abnormalities such as Heart failure, Chronic Obstructive Airway Disease, Pneumonia and Fatty Liver. The involved functions are known as chromophore, Stereochemistry, Cell Respiration, cell transformation and oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. 14r,15s-epetre often locates in Lambda, Cardiovascular system, Blood, Body tissue and Protoplasm. The associated genes with 14r,15s-epetre are CCL2 gene, Cytokine Gene, CYP2C18 gene, CYP2C19 gene and TEK gene. The related lipids are Palmitates.
To understand associated biological information of 14r,15s-epetre, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
14r,15s-epetre is suspected in Heart failure, Chronic Obstructive Airway Disease, Pneumonia, Fatty Liver and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 14r,15s-epetre
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Tse MM et al. | Cytochrome P450 epoxygenase metabolite, 14,15-EET, protects against isoproterenol-induced cellular hypertrophy in H9c2 rat cell line. | 2013 May-Jun | Vascul. Pharmacol. | pmid:23466634 |
Medhora M et al. | Dual regulation of the cerebral microvasculature by epoxyeicosatrienoic acids. | 2001 | Trends Cardiovasc. Med. | pmid:11413051 |
Amara IE et al. | Acute mercury toxicity modulates cytochrome P450, soluble epoxide hydrolase and their associated arachidonic acid metabolites in C57Bl/6 mouse heart. | 2014 | Toxicol. Lett. | pmid:24472606 |
Heizer ML et al. | 14,15-Epoxyeicosatrienoic acid inhibits platelet aggregation in mouse cerebral arterioles. | 1991 | Stroke | pmid:1750047 |
Alkayed NJ et al. | Molecular characterization of an arachidonic acid epoxygenase in rat brain astrocytes. | 1996 | Stroke | pmid:8623121 |
Zhang C and Harder DR | Cerebral capillary endothelial cell mitogenesis and morphogenesis induced by astrocytic epoxyeicosatrienoic Acid. | 2002 | Stroke | pmid:12468797 |
Node K et al. | Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. | 1999 | Science | pmid:10455056 |
Chaudhary KR et al. | Differential effects of soluble epoxide hydrolase inhibition and CYP2J2 overexpression on postischemic cardiac function in aged mice. | 2013 Jul-Aug | Prostaglandins Other Lipid Mediat. | pmid:22922020 |
Yang C et al. | 14,15-Epoxyeicosatrienoic acid induces vasorelaxation through the prostaglandin EP(2) receptors in rat mesenteric artery. | 2010 | Prostaglandins Other Lipid Mediat. | pmid:20601071 |
Skepner JE et al. | Chronic treatment with epoxyeicosatrienoic acids modulates insulin signaling and prevents insulin resistance in hepatocytes. | 2011 | Prostaglandins Other Lipid Mediat. | pmid:21040800 |