Sporková A et al. |
Vasodilatory responses of renal interlobular arteries to epoxyeicosatrienoic acids analog are not enhanced in Ren-2 transgenic hypertensive rats: evidence against a role of direct vascular effects of epoxyeicosatrienoic acids in progression of experimental heart failure. |
2017 |
Physiol Res |
pmid:27782740
|
Li Y et al. |
14,15-Epoxyeicosatrienoic acid suppresses cigarette smoke condensate-induced inflammation in lung epithelial cells by inhibiting autophagy. |
2016 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:27591243
|
El-Sikhry HE et al. |
Novel Roles of Epoxyeicosanoids in Regulating Cardiac Mitochondria. |
2016 |
PLoS ONE |
pmid:27494529
|
Sporková A et al. |
Interlobular Arteries From 2-Kidney, 1-Clip Goldblatt Hypertensive Rats' Exhibit-Impaired Vasodilator Response to Epoxyeicosatrienoic Acids. |
2016 |
Am. J. Med. Sci. |
pmid:27140711
|
Kandhi S et al. |
EETs Elicit Direct Increases in Pulmonary Arterial Pressure in Mice. |
2016 |
Am. J. Hypertens. |
pmid:26304959
|
Yang L et al. |
CYP epoxygenase 2J2 prevents cardiac fibrosis by suppression of transmission of pro-inflammation from cardiomyocytes to macrophages. |
2015 Jan-Mar |
Prostaglandins Other Lipid Mediat. |
pmid:25686540
|
Kandhi S et al. |
EET-dependent potentiation of pulmonary arterial pressure: sex-different regulation of soluble epoxide hydrolase. |
2015 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:26498250
|
Li P et al. |
Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. |
2015 |
Nature |
pmid:26201599
|
Jiang JX et al. |
EETs Attenuate Ox-LDL-Induced LTB4 Production and Activity by Inhibiting p38 MAPK Phosphorylation and 5-LO/BLT1 Receptor Expression in Rat Pulmonary Arterial Endothelial Cells. |
2015 |
PLoS ONE |
pmid:26035589
|
Yu G et al. |
14,15-epoxyeicosatrienoic Acid suppresses cigarette smoke extract-induced apoptosis in lung epithelial cells by inhibiting endoplasmic reticulum stress. |
2015 |
Cell. Physiol. Biochem. |
pmid:25968975
|
Xu J et al. |
Epoxide hydrolase activities and epoxy fatty acids in the mosquito Culex quinquefasciatus. |
2015 |
Insect Biochem. Mol. Biol. |
pmid:25686802
|
Imig JD |
Epoxyeicosatrienoic acids, hypertension, and kidney injury. |
2015 |
Hypertension |
pmid:25583156
|
Chen G et al. |
CYP2J2 overexpression attenuates nonalcoholic fatty liver disease induced by high-fat diet in mice. |
2015 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:25389366
|
Siler DA et al. |
Protective role of p450 epoxyeicosanoids in subarachnoid hemorrhage. |
2015 |
Neurocrit Care |
pmid:25231529
|
Wei X et al. |
Elevated 14,15- epoxyeicosatrienoic acid by increasing of cytochrome P450 2C8, 2C9 and 2J2 and decreasing of soluble epoxide hydrolase associated with aggressiveness of human breast cancer. |
2014 |
BMC Cancer |
pmid:25406731
|
Teder T et al. |
Lipoxygenase-catalyzed transformation of epoxy fatty acids to hydroxy-endoperoxides: a potential P450 and lipoxygenase interaction. |
2014 |
J. Lipid Res. |
pmid:25293588
|
Su KH et al. |
Implication of transient receptor potential vanilloid type 1 in 14,15-epoxyeicosatrienoic acid-induced angiogenesis. |
2014 |
Int. J. Biol. Sci. |
pmid:25210497
|
Falck JR et al. |
14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) surrogates: carboxylate modifications. |
2014 |
J. Med. Chem. |
pmid:25119815
|
Wang X et al. |
CYP2J2-derived epoxyeicosatrienoic acids suppress endoplasmic reticulum stress in heart failure. |
2014 |
Mol. Pharmacol. |
pmid:24145329
|
Althurwi HN et al. |
Fenofibrate modulates cytochrome P450 and arachidonic acid metabolism in the heart and protects against isoproterenol-induced cardiac hypertrophy. |
2014 |
J. Cardiovasc. Pharmacol. |
pmid:24157956
|
Wang L et al. |
14,15-EET promotes mitochondrial biogenesis and protects cortical neurons against oxygen/glucose deprivation-induced apoptosis. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:24931672
|
Amara IE et al. |
Acute mercury toxicity modulates cytochrome P450, soluble epoxide hydrolase and their associated arachidonic acid metabolites in C57Bl/6 mouse heart. |
2014 |
Toxicol. Lett. |
pmid:24472606
|
Diani-Moore S et al. |
Increases in levels of epoxyeicosatrienoic and dihydroxyeicosatrienoic acids (EETs and DHETs) in liver and heart in vivo by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and in hepatic EET:DHET ratios by cotreatment with TCDD and the soluble epoxide hydrolase inhibitor AUDA. |
2014 |
Drug Metab. Dispos. |
pmid:24311719
|
Tse MM et al. |
Cytochrome P450 epoxygenase metabolite, 14,15-EET, protects against isoproterenol-induced cellular hypertrophy in H9c2 rat cell line. |
2013 May-Jun |
Vascul. Pharmacol. |
pmid:23466634
|
Oni-Orisan A et al. |
Dual modulation of cyclooxygenase and CYP epoxygenase metabolism and acute vascular inflammation in mice. |
2013 Jul-Aug |
Prostaglandins Other Lipid Mediat. |
pmid:23000418
|
Chaudhary KR et al. |
Differential effects of soluble epoxide hydrolase inhibition and CYP2J2 overexpression on postischemic cardiac function in aged mice. |
2013 Jul-Aug |
Prostaglandins Other Lipid Mediat. |
pmid:22922020
|
Podolin PL et al. |
In vitro and in vivo characterization of a novel soluble epoxide hydrolase inhibitor. |
2013 Jul-Aug |
Prostaglandins Other Lipid Mediat. |
pmid:23434473
|
Chen L et al. |
Beneficial effects of inhibition of soluble epoxide hydrolase on glucose homeostasis and islet damage in a streptozotocin-induced diabetic mouse model. |
2013 Jul-Aug |
Prostaglandins Other Lipid Mediat. |
pmid:23247129
|
Gross GJ et al. |
Factors mediating remote preconditioning of trauma in the rat heart: central role of the cytochrome p450 epoxygenase pathway in mediating infarct size reduction. |
2013 |
J. Cardiovasc. Pharmacol. Ther. |
pmid:22407888
|
Tabet Y et al. |
Relationship between bradykinin-induced relaxation and endogenous epoxyeicosanoid synthesis in human bronchi. |
2013 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:23418089
|
Pidkovka N et al. |
Epoxyeicosatrienoic acids (EETs) regulate epithelial sodium channel activity by extracellular signal-regulated kinase 1/2 (ERK1/2)-mediated phosphorylation. |
2013 |
J. Biol. Chem. |
pmid:23283969
|
Nelson JW et al. |
Soluble epoxide hydrolase dimerization is required for hydrolase activity. |
2013 |
J. Biol. Chem. |
pmid:23362272
|
Sander AL et al. |
Soluble epoxide hydrolase disruption as therapeutic target for wound healing. |
2013 |
J. Surg. Res. |
pmid:23122666
|
Cracowski JL et al. |
Involvement of cytochrome epoxygenase metabolites in cutaneous postocclusive hyperemia in humans. |
2013 |
J. Appl. Physiol. |
pmid:23172029
|
Gross GJ et al. |
Roles of endothelial nitric oxide synthase (eNOS) and mitochondrial permeability transition pore (MPTP) in epoxyeicosatrienoic acid (EET)-induced cardioprotection against infarction in intact rat hearts. |
2013 |
J. Mol. Cell. Cardiol. |
pmid:23419451
|
Eid S et al. |
20-HETE and EETs in diabetic nephropathy: a novel mechanistic pathway. |
2013 |
PLoS ONE |
pmid:23936373
|
Samokhvalov V et al. |
Epoxyeicosatrienoic acids protect cardiac cells during starvation by modulating an autophagic response. |
2013 |
Cell Death Dis |
pmid:24157879
|
Yang T et al. |
The role of 14,15-dihydroxyeicosatrienoic acid levels in inflammation and its relationship to lipoproteins. |
2013 |
Lipids Health Dis |
pmid:24148690
|
Chadderdon SM et al. |
Activity restriction, impaired capillary function, and the development of insulin resistance in lean primates. |
2012 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:22739105
|
Gupta NC et al. |
Soluble epoxide hydrolase: sex differences and role in endothelial cell survival. |
2012 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:22723436
|
Decker M et al. |
EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides. |
2012 |
J. Lipid Res. |
pmid:22798687
|
Theken KN et al. |
Evaluation of cytochrome P450-derived eicosanoids in humans with stable atherosclerotic cardiovascular disease. |
2012 |
Atherosclerosis |
pmid:22503544
|
Zhang D et al. |
Homocysteine upregulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo. |
2012 |
Circ. Res. |
pmid:22354938
|
Terashvili M et al. |
The protective effect of astrocyte-derived 14,15-epoxyeicosatrienoic acid on hydrogen peroxide-induced cell injury in astrocyte-dopaminergic neuronal cell line co-culture. |
2012 |
Neuroscience |
pmid:22863680
|
Wang SB et al. |
Protection of salvianolic acid A on rat brain from ischemic damage via soluble epoxide hydrolase inhibition. |
2012 |
J Asian Nat Prod Res |
pmid:23106500
|
Herse F et al. |
Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia. |
2012 |
Circulation |
pmid:23155181
|
Li R et al. |
Cytochrome P450 2J2 is protective against global cerebral ischemia in transgenic mice. |
2012 |
Prostaglandins Other Lipid Mediat. |
pmid:23041291
|
Shao J et al. |
P-450-dependent epoxygenase pathway of arachidonic acid is involved in myeloma-induced angiogenesis of endothelial cells. |
2011 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:22038346
|
Zhu P et al. |
Development of a semi-automated LC/MS/MS method for the simultaneous quantitation of 14,15-epoxyeicosatrienoic acid, 14,15-dihydroxyeicosatrienoic acid, leukotoxin and leukotoxin diol in human plasma as biomarkers of soluble epoxide hydrolase activity in vivo. |
2011 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:21798825
|
Sarkar P et al. |
Differential effect of amyloid β on the cytochrome P450 epoxygenase activity in rat brain. |
2011 |
Neuroscience |
pmid:21843605
|