| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Hyperemia | D006940 | 25 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Pre-Eclampsia | D011225 | 16 associated lipids |
| Hypertrophy | D006984 | 16 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Lung Injury | D055370 | 14 associated lipids |
14r,15s-epetre
14r,15s-epetre is a lipid of Fatty Acyls (FA) class. 14r,15s-epetre is associated with abnormalities such as Heart failure, Chronic Obstructive Airway Disease, Pneumonia and Fatty Liver. The involved functions are known as chromophore, Stereochemistry, Cell Respiration, cell transformation and oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. 14r,15s-epetre often locates in Lambda, Cardiovascular system, Blood, Body tissue and Protoplasm. The associated genes with 14r,15s-epetre are CCL2 gene, Cytokine Gene, CYP2C18 gene, CYP2C19 gene and TEK gene. The related lipids are Palmitates.
Cross Reference
Introduction
To understand associated biological information of 14r,15s-epetre, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 14r,15s-epetre?
14r,15s-epetre is suspected in Heart failure, Chronic Obstructive Airway Disease, Pneumonia, Fatty Liver and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Am. J. Physiol. Endocrinol. Metab. (1)
- Am. J. Physiol. Lung Cell Mol. Physiol. (1)
- Prostaglandins Other Lipid Mediat. (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 14r,15s-epetre
PubChem Associated disorders and diseases
What pathways are associated with 14r,15s-epetre
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 14r,15s-epetre?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Am. J. Physiol. Lung Cell Mol. Physiol. (2)
- Am. J. Physiol. Endocrinol. Metab. (1)
- Hypertension (1)
- Others (2)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 14r,15s-epetre?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 14r,15s-epetre?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 14r,15s-epetre?
Related references are published most in these journals:
- Am. J. Physiol. Endocrinol. Metab. (1)
- Am. J. Physiol. Lung Cell Mol. Physiol. (1)
- Hypertension (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 14r,15s-epetre?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 14r,15s-epetre
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Dunn LK et al. | Chick chorioallantoic membrane as an in vivo model to study vasoreactivity: characterization of development-dependent hyperemia induced by epoxyeicosatrienoic acids (EETs). | 2005 | Anat Rec A Discov Mol Cell Evol Biol | pmid:15952186 |
| Lamb DC et al. | Streptomyces coelicolor A3(2) CYP102 protein, a novel fatty acid hydroxylase encoded as a heme domain without an N-terminal redox partner. | 2010 | Appl. Environ. Microbiol. | pmid:20097805 |
| Capdevila J et al. | Influence of a fibric acid type of hypolipidemic agent on the oxidative metabolism of arachidonic acid by liver microsomal cytochrome P-450. | 1985 | Arch. Biochem. Biophys. | pmid:3933431 |
| Oleksiak MF et al. | Identification and regulation of a new vertebrate cytochrome P450 subfamily, the CYP2Ps, and functional characterization of CYP2P3, a conserved arachidonic acid epoxygenase/19-hydroxylase. | 2003 | Arch. Biochem. Biophys. | pmid:12623071 |
| Capdevila JH et al. | NADPH-dependent microsomal metabolism of 14,15-epoxyeicosatrienoic acid to diepoxides and epoxyalcohols. | 1988 | Arch. Biochem. Biophys. | pmid:3341770 |
| Spiecker M and Liao JK | Vascular protective effects of cytochrome p450 epoxygenase-derived eicosanoids. | 2005 | Arch. Biochem. Biophys. | pmid:15581597 |
| Gupta NC et al. | Soluble epoxide hydrolase: sex differences and role in endothelial cell survival. | 2012 | Arterioscler. Thromb. Vasc. Biol. | pmid:22723436 |
| Krötz F et al. | Membrane-potential-dependent inhibition of platelet adhesion to endothelial cells by epoxyeicosatrienoic acids. | 2004 | Arterioscler. Thromb. Vasc. Biol. | pmid:14715644 |
| Theken KN et al. | Evaluation of cytochrome P450-derived eicosanoids in humans with stable atherosclerotic cardiovascular disease. | 2012 | Atherosclerosis | pmid:22503544 |
| Ghosh S et al. | Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats. | 2008 | Basic Clin. Pharmacol. Toxicol. | pmid:18312493 |
| Peri KG et al. | A role for protein kinase C alpha in stimulation of prostaglandin G/H synthase-2 transcription by 14,15-epoxyeicosatrienoic acid. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9514882 |
| Pritchard KA et al. | 14, 15-Epoxyeicosatrienoic acid promotes endothelial cell dependent adhesion of human monocytic tumor U937 cells. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2310385 |
| Lin WK et al. | Effect of 14,15-epoxyeicosatrienoic acid infusion on blood pressure in normal and hypertensive rats. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2322287 |
| Karara A et al. | Arachidonic acid epoxygenase: structural characterization and quantification of epoxyeicosatrienoates in plasma. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1540175 |
| Wang L et al. | 14,15-EET promotes mitochondrial biogenesis and protects cortical neurons against oxygen/glucose deprivation-induced apoptosis. | 2014 | Biochem. Biophys. Res. Commun. | pmid:24931672 |
| Xiao ZL et al. | Demonstration of endogenous inhibitors for the formation of 14,15-oxido-5,8,11-eicosatrienoic acid from phosphatidylinositol in bovine lung extract. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3421969 |
| Capdevila JH et al. | A novel pool of rat liver inositol and ethanolamine phospholipids contains epoxyeicosatrienoic acids (EETs). | 1987 | Biochem. Biophys. Res. Commun. | pmid:3619897 |
| Seki K et al. | Epoxyeicosatrienoic acid stimulates ADP-ribosylation of a 52 kDa protein in rat liver cytosol. | 1992 | Biochem. J. | pmid:1731754 |
| Wu SN et al. | Actions of epoxyeicosatrienoic acid on large-conductance Ca(2+)-activated K(+) channels in pituitary GH(3) cells. | 2000 | Biochem. Pharmacol. | pmid:10825470 |
| Chen Y et al. | 20-Iodo-14,15-epoxyeicosa-8(Z)-enoyl-3-azidophenylsulfonamide: photoaffinity labeling of a 14,15-epoxyeicosatrienoic acid receptor. | 2011 | Biochemistry | pmid:21469660 |