(+/-)8,9-epetre

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 395 references associated with (+/-)8,9-epetre in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for (+/-)8,9-epetre

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (+/-)8,9-epetre

MeSH term MeSH ID Detail
Insulinoma D007340 28 associated lipids
Hyperemia D006940 25 associated lipids
Hypertension D006973 115 associated lipids
Subarachnoid Hemorrhage D013345 17 associated lipids
Hyperhomocysteinemia D020138 6 associated lipids
Total 5

PubChem Biomolecular Interactions and Pathways

All references with (+/-)8,9-epetre

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Authors Title Published Journal PubMed Link
Kandhi S et al. EETs Elicit Direct Increases in Pulmonary Arterial Pressure in Mice. 2016 Am. J. Hypertens. pmid:26304959
Wang X et al. CYP2J2-derived epoxyeicosatrienoic acids suppress endoplasmic reticulum stress in heart failure. 2014 Mol. Pharmacol. pmid:24145329
Althurwi HN et al. Fenofibrate modulates cytochrome P450 and arachidonic acid metabolism in the heart and protects against isoproterenol-induced cardiac hypertrophy. 2014 J. Cardiovasc. Pharmacol. pmid:24157956
Diani-Moore S et al. Increases in levels of epoxyeicosatrienoic and dihydroxyeicosatrienoic acids (EETs and DHETs) in liver and heart in vivo by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and in hepatic EET:DHET ratios by cotreatment with TCDD and the soluble epoxide hydrolase inhibitor AUDA. 2014 Drug Metab. Dispos. pmid:24311719
Strauss KI et al. Altered behavioral phenotypes in soluble epoxide hydrolase knockout mice: effects of traumatic brain injury. 2013 Jul-Aug Prostaglandins Other Lipid Mediat. pmid:22922090
Cracowski JL et al. Involvement of cytochrome epoxygenase metabolites in cutaneous postocclusive hyperemia in humans. 2013 J. Appl. Physiol. pmid:23172029
Klett EL et al. Diminished acyl-CoA synthetase isoform 4 activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion. 2013 J. Biol. Chem. pmid:23766516
Liu Y et al. A soluble epoxide hydrolase inhibitor--8-HUDE increases pulmonary vasoconstriction through inhibition of K(ATP) channels. 2012 Pulm Pharmacol Ther pmid:22155000
Gao Y et al. 8,9-Epoxyeicosatrienoic acid inhibits antibody production of B lymphocytes in mice. 2012 PLoS ONE pmid:22802958
Norton SK et al. Epoxyeicosatrienoic acids are involved in the C(70) fullerene derivative-induced control of allergic asthma. 2012 J. Allergy Clin. Immunol. pmid:22664166
Pavlov TS et al. Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC). 2011 Am. J. Physiol. Renal Physiol. pmid:21697242
Jiang H et al. Increases in plasma trans-EETs and blood pressure reduction in spontaneously hypertensive rats. 2011 Am. J. Physiol. Heart Circ. Physiol. pmid:21398593
Brenneis C et al. Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation. 2011 Mol Pain pmid:21970373
Ma J et al. 8,9-Epoxyeicosatrienoic acid analog protects pulmonary artery smooth muscle cells from apoptosis via ROCK pathway. 2010 Exp. Cell Res. pmid:20493836
Sharma M et al. 8,9-Epoxyeicosatrienoic acid protects the glomerular filtration barrier. 2009 Prostaglandins Other Lipid Mediat. pmid:19480064
Miller TM et al. Rapid, simultaneous quantitation of mono and dioxygenated metabolites of arachidonic acid in human CSF and rat brain. 2009 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:19892608
Moshal KS et al. Cytochrome P450 (CYP) 2J2 gene transfection attenuates MMP-9 via inhibition of NF-kappabeta in hyperhomocysteinemia. 2008 J. Cell. Physiol. pmid:18181170
Jiang JG et al. Regulation of endothelial nitric-oxide synthase activity through phosphorylation in response to epoxyeicosatrienoic acids. 2007 Prostaglandins Other Lipid Mediat. pmid:17164144
Gross GJ et al. Mechanisms by which epoxyeicosatrienoic acids (EETs) elicit cardioprotection in rat hearts. 2007 J. Mol. Cell. Cardiol. pmid:17217955
Vriens J et al. Determinants of 4 alpha-phorbol sensitivity in transmembrane domains 3 and 4 of the cation channel TRPV4. 2007 J. Biol. Chem. pmid:17341586
Sacerdoti D et al. Rat mesenteric arterial dilator response to 11,12-epoxyeicosatrienoic acid is mediated by activating heme oxygenase. 2006 Am. J. Physiol. Heart Circ. Physiol. pmid:16798831
Wang XL et al. Inhibition of ATP binding to the carboxyl terminus of Kir6.2 by epoxyeicosatrienoic acids. 2006 Biochim. Biophys. Acta pmid:16904368
Wei S et al. Chiral resolution of the epoxyeicosatrienoic acids, arachidonic acid epoxygenase metabolites. 2006 Anal. Biochem. pmid:16480681
Vriens J et al. Modulation of the Ca2 permeable cation channel TRPV4 by cytochrome P450 epoxygenases in vascular endothelium. 2005 Circ. Res. pmid:16179585
Ye D et al. Activation of rat mesenteric arterial KATP channels by 11,12-epoxyeicosatrienoic acid. 2005 Am. J. Physiol. Heart Circ. Physiol. pmid:15331373
Lu T et al. Molecular determinants of cardiac K(ATP) channel activation by epoxyeicosatrienoic acids. 2005 J. Biol. Chem. pmid:15760904
Spiecker M and Liao JK Vascular protective effects of cytochrome p450 epoxygenase-derived eicosanoids. 2005 Arch. Biochem. Biophys. pmid:15581597
Pozzi A et al. Characterization of 5,6- and 8,9-epoxyeicosatrienoic acids (5,6- and 8,9-EET) as potent in vivo angiogenic lipids. 2005 J. Biol. Chem. pmid:15917237
Dunn LK et al. Chick chorioallantoic membrane as an in vivo model to study vasoreactivity: characterization of development-dependent hyperemia induced by epoxyeicosatrienoic acids (EETs). 2005 Anat Rec A Discov Mol Cell Evol Biol pmid:15952186
Alvarez DF et al. Role of EETs in regulation of endothelial permeability in rat lung. 2004 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:14578116
Krötz F et al. Membrane-potential-dependent inhibition of platelet adhesion to endothelial cells by epoxyeicosatrienoic acids. 2004 Arterioscler. Thromb. Vasc. Biol. pmid:14715644
Michaelis UR et al. Cytochrome P450 2C9-derived epoxyeicosatrienoic acids induce angiogenesis via cross-talk with the epidermal growth factor receptor (EGFR). 2003 FASEB J. pmid:12586744
Salvail D et al. Functional reconstitution of an eicosanoid-modulated Cl- channel from bovine tracheal smooth muscle. 2002 Am. J. Physiol., Cell Physiol. pmid:11832342
Gauthier KM et al. 14,15-Epoxyeicosa-5(Z)-enoic acid: a selective epoxyeicosatrienoic acid antagonist that inhibits endothelium-dependent hyperpolarization and relaxation in coronary arteries. 2002 Circ. Res. pmid:12016270
Zhang C and Harder DR Cerebral capillary endothelial cell mitogenesis and morphogenesis induced by astrocytic epoxyeicosatrienoic Acid. 2002 Stroke pmid:12468797
Krishna UM et al. Stereospecific synthesis of trans-arachidonic acids. 2001 Bioorg. Med. Chem. Lett. pmid:11549436
Lu T et al. Activation of ATP-sensitive K(+) channels by epoxyeicosatrienoic acids in rat cardiac ventricular myocytes. 2001 J. Physiol. (Lond.) pmid:11744757
Zhang Y et al. EET homologs potently dilate coronary microvessels and activate BK(Ca) channels. 2001 Am. J. Physiol. Heart Circ. Physiol. pmid:11356595
Benoit C et al. EETs relax airway smooth muscle via an EpDHF effect: BK(Ca) channel activation and hyperpolarization. 2001 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:11290521
Medhora M et al. Dual regulation of the cerebral microvasculature by epoxyeicosatrienoic acids. 2001 Trends Cardiovasc. Med. pmid:11413051
Imig JD et al. Enhanced renal microvascular reactivity to angiotensin II in hypertension is ameliorated by the sulfonimide analog of 11,12-epoxyeicosatrienoic acid. 2001 J. Hypertens. pmid:11393683
Node K et al. Activation of Galpha s mediates induction of tissue-type plasminogen activator gene transcription by epoxyeicosatrienoic acids. 2001 J. Biol. Chem. pmid:11279071
Pomposiello SI et al. Epoxyeicosatrienoic acid-mediated renal vasodilation to arachidonic acid is enhanced in SHR. 2001 Hypertension pmid:11244013
Nithipatikom K et al. Determination of EETs using microbore liquid chromatography with fluorescence detection. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:10924087
Zhang Y et al. Arachidonic acid modulation of alpha1H, a cloned human T-type calcium channel. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:10644598
Zhu D et al. Epoxyeicosatrienoic acids constrict isolated pressurized rabbit pulmonary arteries. 2000 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:10666118
Yu Z et al. Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. 2000 Circ. Res. pmid:11090543
Kiss L et al. Synthesis of arachidonic acid-derived lipoxygenase and cytochrome P450 products in the intact human lung vasculature. 2000 Am. J. Respir. Crit. Care Med. pmid:10852767
Node K et al. Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. 1999 Science pmid:10455056
Fang X et al. Epoxyeicosatrienoic acids increase intracellular calcium concentration in vascular smooth muscle cells. 1999 Hypertension pmid:10601125

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