| MeSH term | MeSH ID | Detail |
|---|---|---|
| Brain Ischemia | D002545 | 89 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperemia | D006940 | 25 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Hypertrophy | D006984 | 16 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Pre-Eclampsia | D011225 | 16 associated lipids |
| Coronary Occlusion | D054059 | 4 associated lipids |
14,15-eet
14,15-eet is a lipid of Fatty Acyls (FA) class. 14,15-eet is associated with abnormalities such as Heart failure, Chronic Obstructive Airway Disease, Pneumonia and Fatty Liver. The involved functions are known as chromophore, Stereochemistry, Cell Respiration, cell transformation and oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. 14,15-eet often locates in Lambda, Cardiovascular system, Blood, Body tissue and Protoplasm. The associated genes with 14,15-eet are CCL2 gene, Cytokine Gene, CYP2C18 gene, CYP2C19 gene and TEK gene. The related lipids are Palmitates.
Cross Reference
Introduction
To understand associated biological information of 14,15-eet, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 14,15-eet?
14,15-eet is suspected in Heart failure, Chronic Obstructive Airway Disease, Pneumonia, Fatty Liver and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Am. J. Physiol. Endocrinol. Metab. (1)
- Am. J. Physiol. Lung Cell Mol. Physiol. (1)
- Prostaglandins Other Lipid Mediat. (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 14,15-eet
PubChem Associated disorders and diseases
What pathways are associated with 14,15-eet
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 14,15-eet?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Am. J. Physiol. Lung Cell Mol. Physiol. (2)
- J. Lipid Res. (1)
- Am. J. Physiol. Endocrinol. Metab. (1)
- Others (2)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 14,15-eet?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 14,15-eet?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 14,15-eet?
Related references are published most in these journals:
- Am. J. Physiol. Endocrinol. Metab. (1)
- Am. J. Physiol. Lung Cell Mol. Physiol. (1)
- Hypertension (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 14,15-eet?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 14,15-eet
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sporková A et al. | Vasodilatory responses of renal interlobular arteries to epoxyeicosatrienoic acids analog are not enhanced in Ren-2 transgenic hypertensive rats: evidence against a role of direct vascular effects of epoxyeicosatrienoic acids in progression of experimental heart failure. | 2017 | Physiol Res | pmid:27782740 |
| Li Y et al. | 14,15-Epoxyeicosatrienoic acid suppresses cigarette smoke condensate-induced inflammation in lung epithelial cells by inhibiting autophagy. | 2016 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:27591243 |
| El-Sikhry HE et al. | Novel Roles of Epoxyeicosanoids in Regulating Cardiac Mitochondria. | 2016 | PLoS ONE | pmid:27494529 |
| Sporková A et al. | Interlobular Arteries From 2-Kidney, 1-Clip Goldblatt Hypertensive Rats' Exhibit-Impaired Vasodilator Response to Epoxyeicosatrienoic Acids. | 2016 | Am. J. Med. Sci. | pmid:27140711 |
| Kandhi S et al. | EETs Elicit Direct Increases in Pulmonary Arterial Pressure in Mice. | 2016 | Am. J. Hypertens. | pmid:26304959 |
| Yang L et al. | CYP epoxygenase 2J2 prevents cardiac fibrosis by suppression of transmission of pro-inflammation from cardiomyocytes to macrophages. | 2015 Jan-Mar | Prostaglandins Other Lipid Mediat. | pmid:25686540 |
| Yu G et al. | 14,15-epoxyeicosatrienoic Acid suppresses cigarette smoke extract-induced apoptosis in lung epithelial cells by inhibiting endoplasmic reticulum stress. | 2015 | Cell. Physiol. Biochem. | pmid:25968975 |
| Xu J et al. | Epoxide hydrolase activities and epoxy fatty acids in the mosquito Culex quinquefasciatus. | 2015 | Insect Biochem. Mol. Biol. | pmid:25686802 |
| Imig JD | Epoxyeicosatrienoic acids, hypertension, and kidney injury. | 2015 | Hypertension | pmid:25583156 |
| Chen G et al. | CYP2J2 overexpression attenuates nonalcoholic fatty liver disease induced by high-fat diet in mice. | 2015 | Am. J. Physiol. Endocrinol. Metab. | pmid:25389366 |