Xu J et al. |
Epoxide hydrolase activities and epoxy fatty acids in the mosquito Culex quinquefasciatus. |
2015 |
Insect Biochem. Mol. Biol. |
pmid:25686802
|
Kopf PG et al. |
Angiotensin II regulates adrenal vascular tone through zona glomerulosa cell-derived EETs and DHETs. |
2011 |
Hypertension |
pmid:21199991
|
Imig JD |
Epoxyeicosatrienoic acids, hypertension, and kidney injury. |
2015 |
Hypertension |
pmid:25583156
|
Fisslthaler B et al. |
Cyclic stretch enhances the expression and activity of coronary endothelium-derived hyperpolarizing factor synthase. |
2001 |
Hypertension |
pmid:11751730
|
Gauthier KM et al. |
14,15-epoxyeicosa-5(Z)-enoic-mSI: a 14,15- and 5,6-EET antagonist in bovine coronary arteries. |
2003 |
Hypertension |
pmid:12953017
|
Fang X et al. |
Epoxyeicosatrienoic acids increase intracellular calcium concentration in vascular smooth muscle cells. |
1999 |
Hypertension |
pmid:10601125
|
Gauthier KM et al. |
14,15-epoxyeicosatrienoic acid represents a transferable endothelium-dependent relaxing factor in bovine coronary arteries. |
2005 |
Hypertension |
pmid:15699460
|
Zhu Y et al. |
Identification of arachidonate P-450 metabolites in human platelet phospholipids. |
1995 |
Hypertension |
pmid:7721444
|
Peri KG et al. |
Stimulation of prostaglandin G/H synthase-2 expression by arachidonic acid monoxygenase product, 14,15-epoxyeicosatrienoic acid. |
1997 |
FEBS Lett. |
pmid:9373167
|
Karara A et al. |
Arachidonic acid epoxygenase. Stereochemical analysis of the endogenous epoxyeicosatrienoic acids of human kidney cortex. |
1990 |
FEBS Lett. |
pmid:2384159
|
Liu YC and Wu SN |
Block of erg current by linoleoylamide, a sleep-inducing agent, in pituitary GH3 cells. |
2003 |
Eur. J. Pharmacol. |
pmid:12498905
|
Carroll MA et al. |
Vasoactivity of arachidonic acid epoxides. |
1987 |
Eur. J. Pharmacol. |
pmid:3622613
|
Sridar C et al. |
Anandamide oxidation by wild-type and polymorphically expressed CYP2B6 and CYP2D6. |
2011 |
Drug Metab. Dispos. |
pmid:21289075
|
Diani-Moore S et al. |
Increases in levels of epoxyeicosatrienoic and dihydroxyeicosatrienoic acids (EETs and DHETs) in liver and heart in vivo by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and in hepatic EET:DHET ratios by cotreatment with TCDD and the soluble epoxide hydrolase inhibitor AUDA. |
2014 |
Drug Metab. Dispos. |
pmid:24311719
|
Imaizumi S et al. |
L-4F differentially alters plasma levels of oxidized fatty acids resulting in more anti-inflammatory HDL in mice. |
2010 |
Drug Metab Lett |
pmid:20642447
|
Ward NC et al. |
Cytochrome P450 metabolites of arachidonic acid are elevated in stroke patients compared with healthy controls. |
2011 |
Clin. Sci. |
pmid:21689071
|
Herse F et al. |
Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia. |
2012 |
Circulation |
pmid:23155181
|
Weintraub NL et al. |
Potentiation of endothelium-dependent relaxation by epoxyeicosatrienoic acids. |
1997 |
Circ. Res. |
pmid:9242187
|
Hutcheson IR et al. |
Nitric oxide-independent relaxations to acetylcholine and A23187 involve different routes of heterocellular communication. Role of Gap junctions and phospholipase A2. |
1999 Jan 8-22 |
Circ. Res. |
pmid:9915774
|
Zhang D et al. |
Homocysteine upregulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo. |
2012 |
Circ. Res. |
pmid:22354938
|
Proctor KG et al. |
Intestinal vasodilation by epoxyeicosatrienoic acids: arachidonic acid metabolites produced by a cytochrome P450 monooxygenase. |
1987 |
Circ. Res. |
pmid:3105909
|
Gauthier KM et al. |
14,15-Epoxyeicosa-5(Z)-enoic acid: a selective epoxyeicosatrienoic acid antagonist that inhibits endothelium-dependent hyperpolarization and relaxation in coronary arteries. |
2002 |
Circ. Res. |
pmid:12016270
|
Yu Z et al. |
Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. |
2000 |
Circ. Res. |
pmid:11090543
|
Yu G et al. |
14,15-epoxyeicosatrienoic Acid suppresses cigarette smoke extract-induced apoptosis in lung epithelial cells by inhibiting endoplasmic reticulum stress. |
2015 |
Cell. Physiol. Biochem. |
pmid:25968975
|
Samokhvalov V et al. |
Epoxyeicosatrienoic acids protect cardiac cells during starvation by modulating an autophagic response. |
2013 |
Cell Death Dis |
pmid:24157879
|
Jiang JG et al. |
Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors. |
2005 |
Cancer Res. |
pmid:15930289
|
Wei X et al. |
Elevated 14,15- epoxyeicosatrienoic acid by increasing of cytochrome P450 2C8, 2C9 and 2J2 and decreasing of soluble epoxide hydrolase associated with aggressiveness of human breast cancer. |
2014 |
BMC Cancer |
pmid:25406731
|
Cheranov SY et al. |
An essential role for SRC-activated STAT-3 in 14,15-EET-induced VEGF expression and angiogenesis. |
2008 |
Blood |
pmid:18408167
|
Krishna UM et al. |
Stereospecific synthesis of trans-arachidonic acids. |
2001 |
Bioorg. Med. Chem. Lett. |
pmid:11549436
|
VanRollins M et al. |
Optimization of epoxyeicosatrienoic acid syntheses to test their effects on cerebral blood flow in vivo. |
1995 |
Biochim. Biophys. Acta |
pmid:7786887
|
Zosmer A et al. |
Formation and metabolism of 14,15-epoxyeicosatrienoic acid by human reproductive tissues. |
1995 |
Biochim. Biophys. Acta |
pmid:7548192
|
Wang XL et al. |
Inhibition of ATP binding to the carboxyl terminus of Kir6.2 by epoxyeicosatrienoic acids. |
2006 |
Biochim. Biophys. Acta |
pmid:16904368
|
Chen Y et al. |
20-Iodo-14,15-epoxyeicosa-8(Z)-enoyl-3-azidophenylsulfonamide: photoaffinity labeling of a 14,15-epoxyeicosatrienoic acid receptor. |
2011 |
Biochemistry |
pmid:21469660
|
Wu SN et al. |
Actions of epoxyeicosatrienoic acid on large-conductance Ca(2+)-activated K(+) channels in pituitary GH(3) cells. |
2000 |
Biochem. Pharmacol. |
pmid:10825470
|
Seki K et al. |
Epoxyeicosatrienoic acid stimulates ADP-ribosylation of a 52 kDa protein in rat liver cytosol. |
1992 |
Biochem. J. |
pmid:1731754
|
Peri KG et al. |
A role for protein kinase C alpha in stimulation of prostaglandin G/H synthase-2 transcription by 14,15-epoxyeicosatrienoic acid. |
1998 |
Biochem. Biophys. Res. Commun. |
pmid:9514882
|
Pritchard KA et al. |
14, 15-Epoxyeicosatrienoic acid promotes endothelial cell dependent adhesion of human monocytic tumor U937 cells. |
1990 |
Biochem. Biophys. Res. Commun. |
pmid:2310385
|
Lin WK et al. |
Effect of 14,15-epoxyeicosatrienoic acid infusion on blood pressure in normal and hypertensive rats. |
1990 |
Biochem. Biophys. Res. Commun. |
pmid:2322287
|
Karara A et al. |
Arachidonic acid epoxygenase: structural characterization and quantification of epoxyeicosatrienoates in plasma. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1540175
|
Wang L et al. |
14,15-EET promotes mitochondrial biogenesis and protects cortical neurons against oxygen/glucose deprivation-induced apoptosis. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:24931672
|
Xiao ZL et al. |
Demonstration of endogenous inhibitors for the formation of 14,15-oxido-5,8,11-eicosatrienoic acid from phosphatidylinositol in bovine lung extract. |
1988 |
Biochem. Biophys. Res. Commun. |
pmid:3421969
|
Capdevila JH et al. |
A novel pool of rat liver inositol and ethanolamine phospholipids contains epoxyeicosatrienoic acids (EETs). |
1987 |
Biochem. Biophys. Res. Commun. |
pmid:3619897
|
Ghosh S et al. |
Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats. |
2008 |
Basic Clin. Pharmacol. Toxicol. |
pmid:18312493
|
Theken KN et al. |
Evaluation of cytochrome P450-derived eicosanoids in humans with stable atherosclerotic cardiovascular disease. |
2012 |
Atherosclerosis |
pmid:22503544
|
Gupta NC et al. |
Soluble epoxide hydrolase: sex differences and role in endothelial cell survival. |
2012 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:22723436
|
Krötz F et al. |
Membrane-potential-dependent inhibition of platelet adhesion to endothelial cells by epoxyeicosatrienoic acids. |
2004 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:14715644
|
Capdevila J et al. |
Influence of a fibric acid type of hypolipidemic agent on the oxidative metabolism of arachidonic acid by liver microsomal cytochrome P-450. |
1985 |
Arch. Biochem. Biophys. |
pmid:3933431
|
Oleksiak MF et al. |
Identification and regulation of a new vertebrate cytochrome P450 subfamily, the CYP2Ps, and functional characterization of CYP2P3, a conserved arachidonic acid epoxygenase/19-hydroxylase. |
2003 |
Arch. Biochem. Biophys. |
pmid:12623071
|
Capdevila JH et al. |
NADPH-dependent microsomal metabolism of 14,15-epoxyeicosatrienoic acid to diepoxides and epoxyalcohols. |
1988 |
Arch. Biochem. Biophys. |
pmid:3341770
|
Spiecker M and Liao JK |
Vascular protective effects of cytochrome p450 epoxygenase-derived eicosanoids. |
2005 |
Arch. Biochem. Biophys. |
pmid:15581597
|