| MeSH term | MeSH ID | Detail |
|---|---|---|
| Brain Ischemia | D002545 | 89 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperemia | D006940 | 25 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Hypertrophy | D006984 | 16 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Pre-Eclampsia | D011225 | 16 associated lipids |
| Coronary Occlusion | D054059 | 4 associated lipids |
| Lung Injury | D055370 | 14 associated lipids |
14,15-eet
14,15-eet is a lipid of Fatty Acyls (FA) class. 14,15-eet is associated with abnormalities such as Heart failure, Chronic Obstructive Airway Disease, Pneumonia and Fatty Liver. The involved functions are known as chromophore, Stereochemistry, Cell Respiration, cell transformation and oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. 14,15-eet often locates in Lambda, Cardiovascular system, Blood, Body tissue and Protoplasm. The associated genes with 14,15-eet are CCL2 gene, Cytokine Gene, CYP2C18 gene, CYP2C19 gene and TEK gene. The related lipids are Palmitates.
Cross Reference
Introduction
To understand associated biological information of 14,15-eet, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 14,15-eet?
14,15-eet is suspected in Heart failure, Chronic Obstructive Airway Disease, Pneumonia, Fatty Liver and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Am. J. Physiol. Endocrinol. Metab. (1)
- Am. J. Physiol. Lung Cell Mol. Physiol. (1)
- Prostaglandins Other Lipid Mediat. (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 14,15-eet
PubChem Associated disorders and diseases
What pathways are associated with 14,15-eet
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 14,15-eet?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Am. J. Physiol. Lung Cell Mol. Physiol. (2)
- Am. J. Physiol. Endocrinol. Metab. (1)
- Hypertension (1)
- Others (2)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 14,15-eet?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 14,15-eet?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 14,15-eet?
Related references are published most in these journals:
- Am. J. Physiol. Endocrinol. Metab. (1)
- Am. J. Physiol. Lung Cell Mol. Physiol. (1)
- Hypertension (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 14,15-eet?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 14,15-eet
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tréluyer JM et al. | Ontogenesis of CYP2C-dependent arachidonic acid metabolism in the human liver: relationship with sudden infant death syndrome. | 2000 | Pediatr. Res. | pmid:10813596 |
| Terashvili M et al. | The protective effect of astrocyte-derived 14,15-epoxyeicosatrienoic acid on hydrogen peroxide-induced cell injury in astrocyte-dopaminergic neuronal cell line co-culture. | 2012 | Neuroscience | pmid:22863680 |
| Sarkar P et al. | Differential effect of amyloid β on the cytochrome P450 epoxygenase activity in rat brain. | 2011 | Neuroscience | pmid:21843605 |
| Siler DA et al. | Protective role of p450 epoxyeicosanoids in subarachnoid hemorrhage. | 2015 | Neurocrit Care | pmid:25231529 |
| Li P et al. | Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. | 2015 | Nature | pmid:26201599 |
| Planagumà A et al. | Lovastatin decreases acute mucosal inflammation via 15-epi-lipoxin A4. | 2010 | Mucosal Immunol | pmid:20130564 |
| Zeldin DC et al. | CYP2J subfamily P450s in the lung: expression, localization, and potential functional significance. | 1996 | Mol. Pharmacol. | pmid:8913342 |
| Wang X et al. | CYP2J2-derived epoxyeicosatrienoic acids suppress endoplasmic reticulum stress in heart failure. | 2014 | Mol. Pharmacol. | pmid:24145329 |
| Yu Z et al. | Increased CYP2J expression and epoxyeicosatrienoic acid formation in spontaneously hypertensive rat kidney. | 2000 | Mol. Pharmacol. | pmid:10779386 |
| Chen J et al. | Mitogenic activity and signaling mechanism of 2-(14,15- epoxyeicosatrienoyl)glycerol, a novel cytochrome p450 arachidonate metabolite. | 2007 | Mol. Cell. Biol. | pmid:17283047 |