14,15-eet

14,15-eet is a lipid of Fatty Acyls (FA) class. 14,15-eet is associated with abnormalities such as Heart failure, Chronic Obstructive Airway Disease, Pneumonia and Fatty Liver. The involved functions are known as chromophore, Stereochemistry, Cell Respiration, cell transformation and oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. 14,15-eet often locates in Lambda, Cardiovascular system, Blood, Body tissue and Protoplasm. The associated genes with 14,15-eet are CCL2 gene, Cytokine Gene, CYP2C18 gene, CYP2C19 gene and TEK gene. The related lipids are Palmitates.

Cross Reference

Introduction

To understand associated biological information of 14,15-eet, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 14,15-eet?

14,15-eet is suspected in Heart failure, Chronic Obstructive Airway Disease, Pneumonia, Fatty Liver and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 14,15-eet

MeSH term MeSH ID Detail
Coronary Occlusion D054059 4 associated lipids
Lung Injury D055370 14 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Hypertrophy D006984 16 associated lipids
Hyperemia D006940 25 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Brain Ischemia D002545 89 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Insulin Resistance D007333 99 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 14,15-eet

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 14,15-eet?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 14,15-eet?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 14,15-eet?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 14,15-eet?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 14,15-eet?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 14,15-eet

Download all related citations
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Authors Title Published Journal PubMed Link
Zhang Y et al. EET homologs potently dilate coronary microvessels and activate BK(Ca) channels. 2001 Am. J. Physiol. Heart Circ. Physiol. pmid:11356595
Rastaldo R et al. Cytochrome P-450 metabolite of arachidonic acid mediates bradykinin-induced negative inotropic effect. 2001 Am. J. Physiol. Heart Circ. Physiol. pmid:11356641
Imig JD et al. Enhanced renal microvascular reactivity to angiotensin II in hypertension is ameliorated by the sulfonimide analog of 11,12-epoxyeicosatrienoic acid. 2001 J. Hypertens. pmid:11393683
Medhora M et al. Dual regulation of the cerebral microvasculature by epoxyeicosatrienoic acids. 2001 Trends Cardiovasc. Med. pmid:11413051
Krishna UM et al. Stereospecific synthesis of trans-arachidonic acids. 2001 Bioorg. Med. Chem. Lett. pmid:11549436
Miller AW et al. Epoxyeicosatrienoic acid-induced relaxation is impaired in insulin resistance. 2001 Am. J. Physiol. Heart Circ. Physiol. pmid:11557540
Fisslthaler B et al. Cyclic stretch enhances the expression and activity of coronary endothelium-derived hyperpolarizing factor synthase. 2001 Hypertension pmid:11751730
Salvail D et al. Functional reconstitution of an eicosanoid-modulated Cl- channel from bovine tracheal smooth muscle. 2002 Am. J. Physiol., Cell Physiol. pmid:11832342
Campbell WB et al. 14,15-Dihydroxyeicosatrienoic acid relaxes bovine coronary arteries by activation of K(Ca) channels. 2002 Am. J. Physiol. Heart Circ. Physiol. pmid:11959628
Gauthier KM et al. 14,15-Epoxyeicosa-5(Z)-enoic acid: a selective epoxyeicosatrienoic acid antagonist that inhibits endothelium-dependent hyperpolarization and relaxation in coronary arteries. 2002 Circ. Res. pmid:12016270