14,15-eet

14,15-eet is a lipid of Fatty Acyls (FA) class. 14,15-eet is associated with abnormalities such as Heart failure, Chronic Obstructive Airway Disease, Pneumonia and Fatty Liver. The involved functions are known as chromophore, Stereochemistry, Cell Respiration, cell transformation and oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. 14,15-eet often locates in Lambda, Cardiovascular system, Blood, Body tissue and Protoplasm. The associated genes with 14,15-eet are CCL2 gene, Cytokine Gene, CYP2C18 gene, CYP2C19 gene and TEK gene. The related lipids are Palmitates.

Cross Reference

Introduction

To understand associated biological information of 14,15-eet, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 14,15-eet?

14,15-eet is suspected in Heart failure, Chronic Obstructive Airway Disease, Pneumonia, Fatty Liver and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 14,15-eet

MeSH term MeSH ID Detail
Diabetic Nephropathies D003928 39 associated lipids
Hyperemia D006940 25 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Brain Ischemia D002545 89 associated lipids
Hypertension D006973 115 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Hypertrophy D006984 16 associated lipids
Insulin Resistance D007333 99 associated lipids
Lung Injury D055370 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 14,15-eet

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 14,15-eet?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 14,15-eet?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 14,15-eet?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 14,15-eet?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 14,15-eet?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 14,15-eet

Download all related citations
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Authors Title Published Journal PubMed Link
Xiao ZL et al. Demonstration of endogenous inhibitors for the formation of 14,15-oxido-5,8,11-eicosatrienoic acid from phosphatidylinositol in bovine lung extract. 1988 Biochem. Biophys. Res. Commun. pmid:3421969
Capdevila JH et al. NADPH-dependent microsomal metabolism of 14,15-epoxyeicosatrienoic acid to diepoxides and epoxyalcohols. 1988 Arch. Biochem. Biophys. pmid:3341770
Karara A et al. Endogenous epoxyeicosatrienoic acids. Cytochrome P-450 controlled stereoselectivity of the hepatic arachidonic acid epoxygenase. 1989 J. Biol. Chem. pmid:2584196
Hammonds TD et al. Resolution of epoxyeicosatrienoate enantiomers by chiral phase chromatography. 1989 Anal. Biochem. pmid:2610347
Snyder GD et al. Effect of epoxyeicosatrienoic acids on growth hormone release from somatotrophs. 1989 Am. J. Physiol. pmid:2563927
Patel L et al. Production of epoxygenase metabolite by human reproductive tissues. 1989 Prostaglandins pmid:2517348
Pritchard KA et al. 14, 15-Epoxyeicosatrienoic acid promotes endothelial cell dependent adhesion of human monocytic tumor U937 cells. 1990 Biochem. Biophys. Res. Commun. pmid:2310385
Lin WK et al. Effect of 14,15-epoxyeicosatrienoic acid infusion on blood pressure in normal and hypertensive rats. 1990 Biochem. Biophys. Res. Commun. pmid:2322287
Ellis EF et al. Dilation of cerebral arterioles by cytochrome P-450 metabolites of arachidonic acid. 1990 Am. J. Physiol. pmid:2121049
Harris RC et al. Epoxyeicosatrienoic acids activate Na+/H+ exchange and are mitogenic in cultured rat glomerular mesangial cells. 1990 J. Cell. Physiol. pmid:2167900