11,12-epoxy-8-hydroxyeicosa-5,9,14-trienoic acid

11,12-epoxy-8-hydroxyeicosa-5,9,14-trienoic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 293 references associated with 11,12-epoxy-8-hydroxyeicosa-5,9,14-trienoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Douda DN et al. A lipid mediator hepoxilin A3 is a natural inducer of neutrophil extracellular traps in human neutrophils. 2015 Mediators Inflamm. pmid:25784781
Pazos MA et al. Distinct cellular sources of hepoxilin A3 and leukotriene B4 are used to coordinate bacterial-induced neutrophil transepithelial migration. 2015 J. Immunol. pmid:25548217
Bou Ghanem EN et al. The α-tocopherol form of vitamin E reverses age-associated susceptibility to streptococcus pneumoniae lung infection by modulating pulmonary neutrophil recruitment. 2015 J. Immunol. pmid:25512603
Kubala SA et al. Pathogen induced chemo-attractant hepoxilin A3 drives neutrophils, but not eosinophils across epithelial barriers. 2014 Prostaglandins Other Lipid Mediat. pmid:24315875
Stenson WF The universe of arachidonic acid metabolites in inflammatory bowel disease: can we tell the good from the bad? 2014 Curr. Opin. Gastroenterol. pmid:24837228
Bhowmick R et al. Systemic disease during Streptococcus pneumoniae acute lung infection requires 12-lipoxygenase-dependent inflammation. 2013 J. Immunol. pmid:24089193
Gregus AM et al. Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22493235
Tamang DL et al. Hepoxilin A(3) facilitates neutrophilic breach of lipoxygenase-expressing airway epithelial barriers. 2012 J. Immunol. pmid:23045615
Zafiriou MP et al. Hepoxilin A(3) protects β-cells from apoptosis in contrast to its precursor, 12-hydroperoxyeicosatetraenoic acid. 2011 Biochim. Biophys. Acta pmid:21420506
Cronin A et al. Mammalian soluble epoxide hydrolase is identical to liver hepoxilin hydrolase. 2011 J. Lipid Res. pmid:21217101

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