11,12-epoxy-8-hydroxyeicosa-5,9,14-trienoic acid

11,12-epoxy-8-hydroxyeicosa-5,9,14-trienoic acid is a lipid of Fatty Acyls (FA) class.

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Current reference collection contains 293 references associated with 11,12-epoxy-8-hydroxyeicosa-5,9,14-trienoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Pace-Asciak CR et al. A glutathione conjugate of hepoxilin A3: formation and action in the rat central nervous system. 1990 Proc. Natl. Acad. Sci. U.S.A. pmid:2326264
Piomelli D et al. Formation and action of 8-hydroxy-11,12-epoxy-5,9,14-icosatrienoic acid in Aplysia: a possible second messenger in neurons. 1989 Proc. Natl. Acad. Sci. U.S.A. pmid:2493649
Gregus AM et al. Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22493235
Yu Z et al. The lipoxygenase gene ALOXE3 implicated in skin differentiation encodes a hydroperoxide isomerase. 2003 Proc. Natl. Acad. Sci. U.S.A. pmid:12881489
Margalit A et al. Hepoxilin A3 is the endogenous lipid mediator opposing hypotonic swelling of intact human platelets. 1993 Proc. Natl. Acad. Sci. U.S.A. pmid:8464865
Mrsny RJ et al. Identification of hepoxilin A3 in inflammatory events: a required role in neutrophil migration across intestinal epithelia. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:15123795
Zafiriou MP et al. Biological role of hepoxilins: upregulation of phospholipid hydroperoxide glutathione peroxidase as a cellular response to oxidative stress? 2007 Oct-Nov Prostaglandins Leukot. Essent. Fatty Acids pmid:17997296
Murphy RC and Zarini S Glutathione adducts of oxyeicosanoids. 2002 Prostaglandins Other Lipid Mediat. pmid:12432937
Kubala SA et al. Pathogen induced chemo-attractant hepoxilin A3 drives neutrophils, but not eosinophils across epithelial barriers. 2014 Prostaglandins Other Lipid Mediat. pmid:24315875

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