8s,9r-epetre is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with 8s,9r-epetre
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Insulinoma | D007340 | 28 associated lipids |
| Hyperemia | D006940 | 25 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Subarachnoid Hemorrhage | D013345 | 17 associated lipids |
| Hyperhomocysteinemia | D020138 | 6 associated lipids |
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kandhi S et al. | EETs Elicit Direct Increases in Pulmonary Arterial Pressure in Mice. | 2016 | Am. J. Hypertens. | pmid:26304959 |
| Wang X et al. | CYP2J2-derived epoxyeicosatrienoic acids suppress endoplasmic reticulum stress in heart failure. | 2014 | Mol. Pharmacol. | pmid:24145329 |
| Althurwi HN et al. | Fenofibrate modulates cytochrome P450 and arachidonic acid metabolism in the heart and protects against isoproterenol-induced cardiac hypertrophy. | 2014 | J. Cardiovasc. Pharmacol. | pmid:24157956 |
| Diani-Moore S et al. | Increases in levels of epoxyeicosatrienoic and dihydroxyeicosatrienoic acids (EETs and DHETs) in liver and heart in vivo by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and in hepatic EET:DHET ratios by cotreatment with TCDD and the soluble epoxide hydrolase inhibitor AUDA. | 2014 | Drug Metab. Dispos. | pmid:24311719 |
| Strauss KI et al. | Altered behavioral phenotypes in soluble epoxide hydrolase knockout mice: effects of traumatic brain injury. | 2013 Jul-Aug | Prostaglandins Other Lipid Mediat. | pmid:22922090 |
| Cracowski JL et al. | Involvement of cytochrome epoxygenase metabolites in cutaneous postocclusive hyperemia in humans. | 2013 | J. Appl. Physiol. | pmid:23172029 |
| Klett EL et al. | Diminished acyl-CoA synthetase isoform 4 activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion. | 2013 | J. Biol. Chem. | pmid:23766516 |
| Liu Y et al. | A soluble epoxide hydrolase inhibitor--8-HUDE increases pulmonary vasoconstriction through inhibition of K(ATP) channels. | 2012 | Pulm Pharmacol Ther | pmid:22155000 |
| Gao Y et al. | 8,9-Epoxyeicosatrienoic acid inhibits antibody production of B lymphocytes in mice. | 2012 | PLoS ONE | pmid:22802958 |
| Norton SK et al. | Epoxyeicosatrienoic acids are involved in the C(70) fullerene derivative-induced control of allergic asthma. | 2012 | J. Allergy Clin. Immunol. | pmid:22664166 |
| Pavlov TS et al. | Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC). | 2011 | Am. J. Physiol. Renal Physiol. | pmid:21697242 |
| Jiang H et al. | Increases in plasma trans-EETs and blood pressure reduction in spontaneously hypertensive rats. | 2011 | Am. J. Physiol. Heart Circ. Physiol. | pmid:21398593 |
| Brenneis C et al. | Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation. | 2011 | Mol Pain | pmid:21970373 |
| Ma J et al. | 8,9-Epoxyeicosatrienoic acid analog protects pulmonary artery smooth muscle cells from apoptosis via ROCK pathway. | 2010 | Exp. Cell Res. | pmid:20493836 |
| Sharma M et al. | 8,9-Epoxyeicosatrienoic acid protects the glomerular filtration barrier. | 2009 | Prostaglandins Other Lipid Mediat. | pmid:19480064 |
| Miller TM et al. | Rapid, simultaneous quantitation of mono and dioxygenated metabolites of arachidonic acid in human CSF and rat brain. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19892608 |
| Moshal KS et al. | Cytochrome P450 (CYP) 2J2 gene transfection attenuates MMP-9 via inhibition of NF-kappabeta in hyperhomocysteinemia. | 2008 | J. Cell. Physiol. | pmid:18181170 |
| Jiang JG et al. | Regulation of endothelial nitric-oxide synthase activity through phosphorylation in response to epoxyeicosatrienoic acids. | 2007 | Prostaglandins Other Lipid Mediat. | pmid:17164144 |
| Gross GJ et al. | Mechanisms by which epoxyeicosatrienoic acids (EETs) elicit cardioprotection in rat hearts. | 2007 | J. Mol. Cell. Cardiol. | pmid:17217955 |
| Vriens J et al. | Determinants of 4 alpha-phorbol sensitivity in transmembrane domains 3 and 4 of the cation channel TRPV4. | 2007 | J. Biol. Chem. | pmid:17341586 |
| Sacerdoti D et al. | Rat mesenteric arterial dilator response to 11,12-epoxyeicosatrienoic acid is mediated by activating heme oxygenase. | 2006 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16798831 |
| Wang XL et al. | Inhibition of ATP binding to the carboxyl terminus of Kir6.2 by epoxyeicosatrienoic acids. | 2006 | Biochim. Biophys. Acta | pmid:16904368 |
| Wei S et al. | Chiral resolution of the epoxyeicosatrienoic acids, arachidonic acid epoxygenase metabolites. | 2006 | Anal. Biochem. | pmid:16480681 |
| Vriens J et al. | Modulation of the Ca2 permeable cation channel TRPV4 by cytochrome P450 epoxygenases in vascular endothelium. | 2005 | Circ. Res. | pmid:16179585 |
| Ye D et al. | Activation of rat mesenteric arterial KATP channels by 11,12-epoxyeicosatrienoic acid. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15331373 |
| Lu T et al. | Molecular determinants of cardiac K(ATP) channel activation by epoxyeicosatrienoic acids. | 2005 | J. Biol. Chem. | pmid:15760904 |
| Spiecker M and Liao JK | Vascular protective effects of cytochrome p450 epoxygenase-derived eicosanoids. | 2005 | Arch. Biochem. Biophys. | pmid:15581597 |
| Pozzi A et al. | Characterization of 5,6- and 8,9-epoxyeicosatrienoic acids (5,6- and 8,9-EET) as potent in vivo angiogenic lipids. | 2005 | J. Biol. Chem. | pmid:15917237 |
| Dunn LK et al. | Chick chorioallantoic membrane as an in vivo model to study vasoreactivity: characterization of development-dependent hyperemia induced by epoxyeicosatrienoic acids (EETs). | 2005 | Anat Rec A Discov Mol Cell Evol Biol | pmid:15952186 |
| Alvarez DF et al. | Role of EETs in regulation of endothelial permeability in rat lung. | 2004 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:14578116 |
| Krötz F et al. | Membrane-potential-dependent inhibition of platelet adhesion to endothelial cells by epoxyeicosatrienoic acids. | 2004 | Arterioscler. Thromb. Vasc. Biol. | pmid:14715644 |
| Michaelis UR et al. | Cytochrome P450 2C9-derived epoxyeicosatrienoic acids induce angiogenesis via cross-talk with the epidermal growth factor receptor (EGFR). | 2003 | FASEB J. | pmid:12586744 |
| Salvail D et al. | Functional reconstitution of an eicosanoid-modulated Cl- channel from bovine tracheal smooth muscle. | 2002 | Am. J. Physiol., Cell Physiol. | pmid:11832342 |
| Gauthier KM et al. | 14,15-Epoxyeicosa-5(Z)-enoic acid: a selective epoxyeicosatrienoic acid antagonist that inhibits endothelium-dependent hyperpolarization and relaxation in coronary arteries. | 2002 | Circ. Res. | pmid:12016270 |
| Zhang C and Harder DR | Cerebral capillary endothelial cell mitogenesis and morphogenesis induced by astrocytic epoxyeicosatrienoic Acid. | 2002 | Stroke | pmid:12468797 |
| Krishna UM et al. | Stereospecific synthesis of trans-arachidonic acids. | 2001 | Bioorg. Med. Chem. Lett. | pmid:11549436 |
| Lu T et al. | Activation of ATP-sensitive K(+) channels by epoxyeicosatrienoic acids in rat cardiac ventricular myocytes. | 2001 | J. Physiol. (Lond.) | pmid:11744757 |
| Zhang Y et al. | EET homologs potently dilate coronary microvessels and activate BK(Ca) channels. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11356595 |
| Benoit C et al. | EETs relax airway smooth muscle via an EpDHF effect: BK(Ca) channel activation and hyperpolarization. | 2001 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:11290521 |
| Medhora M et al. | Dual regulation of the cerebral microvasculature by epoxyeicosatrienoic acids. | 2001 | Trends Cardiovasc. Med. | pmid:11413051 |
| Imig JD et al. | Enhanced renal microvascular reactivity to angiotensin II in hypertension is ameliorated by the sulfonimide analog of 11,12-epoxyeicosatrienoic acid. | 2001 | J. Hypertens. | pmid:11393683 |
| Node K et al. | Activation of Galpha s mediates induction of tissue-type plasminogen activator gene transcription by epoxyeicosatrienoic acids. | 2001 | J. Biol. Chem. | pmid:11279071 |
| Pomposiello SI et al. | Epoxyeicosatrienoic acid-mediated renal vasodilation to arachidonic acid is enhanced in SHR. | 2001 | Hypertension | pmid:11244013 |
| Nithipatikom K et al. | Determination of EETs using microbore liquid chromatography with fluorescence detection. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:10924087 |
| Zhang Y et al. | Arachidonic acid modulation of alpha1H, a cloned human T-type calcium channel. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:10644598 |
| Zhu D et al. | Epoxyeicosatrienoic acids constrict isolated pressurized rabbit pulmonary arteries. | 2000 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:10666118 |
| Yu Z et al. | Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. | 2000 | Circ. Res. | pmid:11090543 |
| Kiss L et al. | Synthesis of arachidonic acid-derived lipoxygenase and cytochrome P450 products in the intact human lung vasculature. | 2000 | Am. J. Respir. Crit. Care Med. | pmid:10852767 |
| Lee HC et al. | Effects of epoxyeicosatrienoic acids on the cardiac sodium channels in isolated rat ventricular myocytes. | 1999 | J. Physiol. (Lond.) | pmid:10432346 |
| Node K et al. | Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. | 1999 | Science | pmid:10455056 |
| Fang X et al. | Epoxyeicosatrienoic acids increase intracellular calcium concentration in vascular smooth muscle cells. | 1999 | Hypertension | pmid:10601125 |
| Keeney DS et al. | A keratinocyte-specific epoxygenase, CYP2B12, metabolizes arachidonic acid with unusual selectivity, producing a single major epoxyeicosatrienoic acid. | 1998 | J. Biol. Chem. | pmid:9535921 |
| Oltman CL et al. | Epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids are potent vasodilators in the canine coronary microcirculation. | 1998 | Circ. Res. | pmid:9797342 |
| Weintraub NL et al. | Potentiation of endothelium-dependent relaxation by epoxyeicosatrienoic acids. | 1997 | Circ. Res. | pmid:9242187 |
| Leffler CW and Fedinec AL | Newborn piglet cerebral microvascular responses to epoxyeicosatrienoic acids. | 1997 | Am. J. Physiol. | pmid:9249508 |
| Baron A et al. | Epoxyeicosatrienoic acids activate a high-conductance, Ca(2+)-dependent K + channel on pig coronary artery endothelial cells. | 1997 | J. Physiol. (Lond.) | pmid:9401962 |
| Zeldin DC et al. | CYP2J subfamily P450s in the lung: expression, localization, and potential functional significance. | 1996 | Mol. Pharmacol. | pmid:8913342 |
| VanRollins M et al. | Optimization of epoxyeicosatrienoic acid syntheses to test their effects on cerebral blood flow in vivo. | 1995 | Biochim. Biophys. Acta | pmid:7786887 |
| Fang X et al. | Epoxyeicosatrienoic acid metabolism in arterial smooth muscle cells. | 1995 | J. Lipid Res. | pmid:7666001 |
| Daikh BE et al. | Regio- and stereoselective epoxidation of arachidonic acid by human cytochromes P450 2C8 and 2C9. | 1994 | J. Pharmacol. Exp. Ther. | pmid:7996455 |
| Zeldin DC et al. | Regio- and enantiofacial selectivity of epoxyeicosatrienoic acid hydration by cytosolic epoxide hydrolase. | 1993 | J. Biol. Chem. | pmid:8454612 |
| Homma T et al. | Cyclooxygenase-derived metabolites of 8,9-epoxyeicosatrienoic acid are potent mitogens for cultured rat glomerular mesangial cells. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8447831 |
| Moffat MP et al. | Effects of epoxyeicosatrienoic acids on isolated hearts and ventricular myocytes. | 1993 | Am. J. Physiol. | pmid:8476093 |
| Amruthesh SC et al. | Metabolism of arachidonic acid to epoxyeicosatrienoic acids, hydroxyeicosatetraenoic acids, and prostaglandins in cultured rat hippocampal astrocytes. | 1993 | J. Neurochem. | pmid:8515261 |
| Karara A et al. | Arachidonic acid epoxygenase: structural characterization and quantification of epoxyeicosatrienoates in plasma. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1540175 |
| Zhang JY et al. | Regiospecific and enantioselective metabolism of 8,9-epoxyeicosatrienoic acid by cyclooxygenase. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1543485 |
| Carroll MA et al. | Cyclooxygenase dependency of the renovascular actions of cytochrome P450-derived arachidonate metabolites. | 1992 | J. Pharmacol. Exp. Ther. | pmid:1731035 |
| Gebremedhin D et al. | Mechanism of action of cerebral epoxyeicosatrienoic acids on cerebral arterial smooth muscle. | 1992 | Am. J. Physiol. | pmid:1510149 |
| Heizer ML et al. | 14,15-Epoxyeicosatrienoic acid inhibits platelet aggregation in mouse cerebral arterioles. | 1991 | Stroke | pmid:1750047 |
| Pfister SL et al. | Enhanced synthesis of epoxyeicosatrienoic acids by cholesterol-fed rabbit aorta. | 1991 | Am. J. Physiol. | pmid:1887929 |
| Katoh T et al. | Glomerular stereospecific synthesis and hemodynamic actions of 8,9-epoxyeicosatrienoic acid in rat kidney. | 1991 | Am. J. Physiol. | pmid:1928373 |
| Capdevila JH et al. | Cytochrome P-450 enzyme-specific control of the regio- and enantiofacial selectivity of the microsomal arachidonic acid epoxygenase. | 1990 | J. Biol. Chem. | pmid:2358445 |
| Karara A et al. | Arachidonic acid epoxygenase. Stereochemical analysis of the endogenous epoxyeicosatrienoic acids of human kidney cortex. | 1990 | FEBS Lett. | pmid:2384159 |
| Catella F et al. | Endogenous biosynthesis of arachidonic acid epoxides in humans: increased formation in pregnancy-induced hypertension. | 1990 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2198572 |
| Harris RC et al. | Epoxyeicosatrienoic acids activate Na+/H+ exchange and are mitogenic in cultured rat glomerular mesangial cells. | 1990 | J. Cell. Physiol. | pmid:2167900 |
| Karara A et al. | Endogenous epoxyeicosatrienoic acids. Cytochrome P-450 controlled stereoselectivity of the hepatic arachidonic acid epoxygenase. | 1989 | J. Biol. Chem. | pmid:2584196 |
| Hammonds TD et al. | Resolution of epoxyeicosatrienoate enantiomers by chiral phase chromatography. | 1989 | Anal. Biochem. | pmid:2610347 |
| Snyder GD et al. | Effect of epoxyeicosatrienoic acids on growth hormone release from somatotrophs. | 1989 | Am. J. Physiol. | pmid:2563927 |
| Proctor KG et al. | Intestinal vasodilation by epoxyeicosatrienoic acids: arachidonic acid metabolites produced by a cytochrome P450 monooxygenase. | 1987 | Circ. Res. | pmid:3105909 |
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| Fitzpatrick FA et al. | Inhibition of cyclooxygenase activity and platelet aggregation by epoxyeicosatrienoic acids. Influence of stereochemistry. | 1986 | J. Biol. Chem. | pmid:3095326 |
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