Sakuranetin

Sakuranetin is a lipid of Polyketides (PK) class. Sakuranetin is associated with abnormalities such as and Neurodegenerative Disorders. The involved functions are known as inhibitors, Drug Interactions, aldehyde reductase activity, Antiinflammatory Effect and antagonists. Sakuranetin often locates in Vacuole and Cell surface. The associated genes with Sakuranetin are PTPN1 gene.

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Introduction

To understand associated biological information of Sakuranetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Sakuranetin?

Sakuranetin is suspected in Neurodegenerative Disorders and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Sakuranetin

MeSH term MeSH ID Detail
Acne Vulgaris D000152 35 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Sakuranetin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Sakuranetin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Sakuranetin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Sakuranetin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Sakuranetin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Sakuranetin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Sakuranetin

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Authors Title Published Journal PubMed Link
Katsumata S et al. Xylosylated Detoxification of the Rice Flavonoid Phytoalexin Sakuranetin by the Rice Sheath Blight Fungus Rhizoctonia solani. 2018 Molecules pmid:29382171
Jeong H et al. Hepatic Metabolism of Sakuranetin and Its Modulating Effects on Cytochrome P450s and UDP-Glucuronosyltransferases. 2018 Molecules pmid:29949932
Bittencourt-Mernak MI et al. Prophylactic and therapeutic treatment with the flavonone sakuranetin ameliorates LPS-induced acute lung injury. 2017 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:27881407
Ogawa S et al. OsMYC2, an essential factor for JA-inductive sakuranetin production in rice, interacts with MYC2-like proteins that enhance its transactivation ability. 2017 Sci Rep pmid:28067270
Katsumata S et al. Identification of Sternbin and Naringenin as Detoxified Metabolites from the Rice Flavanone Phytoalexin Sakuranetin by Pyricularia oryzae. 2017 Chem. Biodivers. pmid:27647729
Alam P et al. Inter-species comparative antioxidant assay and HPTLC analysis of sakuranetin in the chloroform and ethanol extracts of aerial parts of Rhus retinorrhoea and Rhus tripartita. 2017 Pharm Biol pmid:28345446
Aires A et al. Analysis of glycosylated flavonoids extracted from sweet-cherry stems, as antibacterial agents against pathogenic Escherichia coli isolates. 2017 Acta Biochim. Pol. pmid:28411365
Sakoda CPP et al. Sakuranetin reverses vascular peribronchial and lung parenchyma remodeling in a murine model of chronic allergic pulmonary inflammation. 2016 Acta Histochem. pmid:27425653
Drira R and Sakamoto K Sakuranetin Induces Melanogenesis in B16BL6 Melanoma Cells through Inhibition of ERK and PI3K/AKT Signaling Pathways. 2016 Phytother Res pmid:27000529
Yamashita Y et al. Simple Synthesis of Sakuranetin and Selinone via a Common Intermediate, Utilizing Complementary Regioselectivity in the Deacetylation of Naringenin Triacetate. 2016 Chem. Pharm. Bull. pmid:27373654
Hong L and Ying SH Ethanol extract and isolated constituents from artemisia dracunculus inhibit esophageal squamous cell carcinoma and induce apoptotic cell death. 2015 Drug Res (Stuttg) pmid:25076224
Siciliano I et al. Jasmonic Acid, Abscisic Acid, and Salicylic Acid Are Involved in the Phytoalexin Responses of Rice to Fusarium fujikuroi, a High Gibberellin Producer Pathogen. 2015 J. Agric. Food Chem. pmid:26323788
Taguchi L et al. A flavanone from Baccharis retusa (Asteraceae) prevents elastase-induced emphysema in mice by regulating NF-κB, oxidative stress and metalloproteinases. 2015 Respir. Res. pmid:26122092
Hasegawa M et al. Analysis on blast fungus-responsive characters of a flavonoid phytoalexin sakuranetin; accumulation in infected rice leaves, antifungal activity and detoxification by fungus. 2014 Molecules pmid:25093982
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Lutz JA et al. A nicotinic receptor-mediated anti-inflammatory effect of the flavonoid rhamnetin in BV2 microglia. 2014 Fitoterapia pmid:24972350
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Shimizu T et al. Purification and identification of naringenin 7-O-methyltransferase, a key enzyme in biosynthesis of flavonoid phytoalexin sakuranetin in rice. 2012 J. Biol. Chem. pmid:22493492
Zhou HF et al. Biflavonoids from Caper (Capparis spinosa L.) fruits and their effects in inhibiting NF-kappa B activation. 2011 J. Agric. Food Chem. pmid:21381749
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Chen JJ et al. Dihydroagarofuranoid sesquiterpenes, a lignan derivative, a benzenoid, and antitubercular constituents from the stem of Microtropis japonica. 2008 J. Nat. Prod. pmid:18471021
Takemoto JK et al. Stereospecific analysis of sakuranetin by high-performance liquid chromatography: pharmacokinetic and botanical applications. 2008 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:18676186
Saito T et al. Sakuranetin induces adipogenesis of 3T3-L1 cells through enhanced expression of PPARgamma2. 2008 Biochem. Biophys. Res. Commun. pmid:18522800
Zhang L et al. Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay. 2008 Protein Sci. pmid:18780820
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