Dioclein

Dioclein is a lipid of Polyketides (PK) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 85 references associated with Dioclein in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Dioclein

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Dioclein

MeSH term MeSH ID Detail
Hypotension D007022 41 associated lipids
Total 1

NCBI Entrez Crosslinks

All references with Dioclein

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Authors Title Published Journal PubMed Link
pmid:
Côrtes SF et al. Pharmacological evidence for the activation of potassium channels as the mechanism involved in the hypotensive and vasorelaxant effect of dioclein in rat small resistance arteries. 2001 Br. J. Pharmacol. pmid:11454658
Lemos VS et al. Dioclein, a new nitric oxide- and endothelium-dependent vasodilator flavonoid. 1999 Eur. J. Pharmacol. pmid:10611462
Gonçalves RL et al. The flavonoid dioclein is a selective inhibitor of cyclic nucleotide phosphodiesterase type 1 (PDE1) and a cGMP-dependent protein kinase (PKG) vasorelaxant in human vascular tissue. 2009 Eur. J. Pharmacol. pmid:19686719
Guabiraba R et al. The flavonoid dioclein reduces the production of pro-inflammatory mediators in vitro by inhibiting PDE4 activity and scavenging reactive oxygen species. 2010 Eur. J. Pharmacol. pmid:20152831
Rezende BA et al. Complexation with beta-cyclodextrin confers oral activity on the flavonoid dioclein. 2009 Int J Pharm pmid:18955122
Batista JS et al. Analgesic effect of Dioclea grandiflora constituents in rodents. 1995 J Ethnopharmacol pmid:7623485
Mota VG et al. Antinociceptive activity of the chloroform fraction of Dioclea virgata (Rich.) Amshoff (Fabaceae) in mice. 2011 J. Biomed. Biotechnol. pmid:21776190
da Silveira e Sá Rde C et al. Antinociceptive and toxicological effects of Dioclea grandiflora seed pod in mice. 2010 J. Biomed. Biotechnol. pmid:20368784
Trigueiro F et al. Endothelium-independent vasorelaxant effect of dioclein, a new flavonoid isolated from Dioclea grandiflora, in the rat aorta. 2000 J. Pharm. Pharmacol. pmid:11186253