MeSH term | MeSH ID | Detail |
---|---|---|
Hypotension | D007022 | 41 associated lipids |
Total
1
Dioclein is a lipid of Polyketides (PK) class.
We collected disease MeSH terms mapped to the references associated with Dioclein
MeSH term | MeSH ID | Detail |
---|---|---|
Hypotension | D007022 | 41 associated lipids |
Authors | Title | Published | Journal | PubMed Link |
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pmid: | ||||
Côrtes SF et al. | Pharmacological evidence for the activation of potassium channels as the mechanism involved in the hypotensive and vasorelaxant effect of dioclein in rat small resistance arteries. | 2001 | Br. J. Pharmacol. | pmid:11454658 |
Lemos VS et al. | Dioclein, a new nitric oxide- and endothelium-dependent vasodilator flavonoid. | 1999 | Eur. J. Pharmacol. | pmid:10611462 |
Gonçalves RL et al. | The flavonoid dioclein is a selective inhibitor of cyclic nucleotide phosphodiesterase type 1 (PDE1) and a cGMP-dependent protein kinase (PKG) vasorelaxant in human vascular tissue. | 2009 | Eur. J. Pharmacol. | pmid:19686719 |
Guabiraba R et al. | The flavonoid dioclein reduces the production of pro-inflammatory mediators in vitro by inhibiting PDE4 activity and scavenging reactive oxygen species. | 2010 | Eur. J. Pharmacol. | pmid:20152831 |
Rezende BA et al. | Complexation with beta-cyclodextrin confers oral activity on the flavonoid dioclein. | 2009 | Int J Pharm | pmid:18955122 |
Batista JS et al. | Analgesic effect of Dioclea grandiflora constituents in rodents. | 1995 | J Ethnopharmacol | pmid:7623485 |
Mota VG et al. | Antinociceptive activity of the chloroform fraction of Dioclea virgata (Rich.) Amshoff (Fabaceae) in mice. | 2011 | J. Biomed. Biotechnol. | pmid:21776190 |
da Silveira e Sá Rde C et al. | Antinociceptive and toxicological effects of Dioclea grandiflora seed pod in mice. | 2010 | J. Biomed. Biotechnol. | pmid:20368784 |
Trigueiro F et al. | Endothelium-independent vasorelaxant effect of dioclein, a new flavonoid isolated from Dioclea grandiflora, in the rat aorta. | 2000 | J. Pharm. Pharmacol. | pmid:11186253 |