Hxa3

Hxa3 is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 289 references associated with Hxa3 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Hxa3

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Hxa3

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Lung Diseases D008171 37 associated lipids
Total 2

PubChem Biomolecular Interactions and Pathways

All references with Hxa3

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Authors Title Published Journal PubMed Link
Nigam S and Zafiriou MP Hepoxilin A3 synthase. 2005 Biochem. Biophys. Res. Commun. pmid:16198304
Hurley BP et al. Polymorphonuclear cell transmigration induced by Pseudomonas aeruginosa requires the eicosanoid hepoxilin A3. 2004 J. Immunol. pmid:15494523
Mrsny RJ et al. Identification of hepoxilin A3 in inflammatory events: a required role in neutrophil migration across intestinal epithelia. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:15123795
Vogan CL et al. Hepoxilins and trioxilins in barnacles: an analysis of their potential roles in egg hatching and larval settlement. 2003 J. Exp. Biol. pmid:12909703
Reynaud D et al. Hepoxilin signaling in intact human neutrophils: biphasic elevation of intracellular calcium by unesterified hepoxilin A3. 1999 FEBS Lett. pmid:10100848
Wang MM et al. In vivo stimulation of 12(S)-lipoxygenase in the rat skin by bradykinin and platelet activating factor: formation of 12(S)-HETE and hepoxilins, and actions on vascular permeability. 1999 Biochim. Biophys. Acta pmid:9989266
Antón R et al. Occurrence of hepoxilins and trioxilins in psoriatic lesions. 1998 J. Invest. Dermatol. pmid:9540966
Reynaud D and Pace-Asciak CR Docosahexaenoic acid causes accumulation of free arachidonic acid in rat pineal gland and hippocampus to form hepoxilins from both substrates. 1997 Biochim. Biophys. Acta pmid:9219915
Reynaud D et al. Hepoxilin A3 is oxidized by human neutrophils into its omega-hydroxy metabolite by an activity independent of LTB4 omega-hydroxylase. 1997 Biochim. Biophys. Acta pmid:9366245
Mills L et al. Hepoxilin-evoked intracellular reorganization of calcium in human neutrophils: a confocal microscopy study. 1997 Exp. Cell Res. pmid:9024792

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