MeSH term | MeSH ID | Detail |
---|---|---|
Lung Diseases | D008171 | 37 associated lipids |
Inflammation | D007249 | 119 associated lipids |
Total
2
Hxa3 is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Hxa3
MeSH term | MeSH ID | Detail |
---|---|---|
Lung Diseases | D008171 | 37 associated lipids |
Inflammation | D007249 | 119 associated lipids |
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
pmid: | ||||
Reynaud D et al. | Hepoxilin signaling in intact human neutrophils: biphasic elevation of intracellular calcium by unesterified hepoxilin A3. | 1999 | FEBS Lett. | pmid:10100848 |
Vogan CL et al. | Hepoxilins and trioxilins in barnacles: an analysis of their potential roles in egg hatching and larval settlement. | 2003 | J. Exp. Biol. | pmid:12909703 |
Laneuville O et al. | Neurokinin A-induced contraction of guinea-pig isolated trachea: potentiation by hepoxilins. | 1992 | Br. J. Pharmacol. | pmid:1335339 |
Mrsny RJ et al. | Identification of hepoxilin A3 in inflammatory events: a required role in neutrophil migration across intestinal epithelia. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15123795 |
Hurley BP et al. | Polymorphonuclear cell transmigration induced by Pseudomonas aeruginosa requires the eicosanoid hepoxilin A3. | 2004 | J. Immunol. | pmid:15494523 |
Laneuville O et al. | Hepoxilins sensitize blood vessels to noradrenaline--stereospecificity of action. | 1992 | Br. J. Pharmacol. | pmid:1559126 |
Nigam S and Zafiriou MP | Hepoxilin A3 synthase. | 2005 | Biochem. Biophys. Res. Commun. | pmid:16198304 |
Hurley BP et al. | Involvement of phospholipase A2 in Pseudomonas aeruginosa-mediated PMN transepithelial migration. | 2006 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:16272174 |
Pace-Asciak CR et al. | Hepoxilin analogs, potential new therapeutics in disease. | 2006 | Curr. Pharm. Des. | pmid:16533163 |
Laneuville O et al. | Hepoxilin A3 (HxA3) is formed by the rat aorta and is metabolized into HxA3-C, a glutathione conjugate. | 1991 | Biochim. Biophys. Acta | pmid:1675872 |
Yu Z et al. | Epidermal lipoxygenase products of the hepoxilin pathway selectively activate the nuclear receptor PPARalpha. | 2007 | Lipids | pmid:17436029 |
McCormick BA | Bacterial-induced hepoxilin A3 secretion as a pro-inflammatory mediator. | 2007 | FEBS J. | pmid:17608718 |
Zafiriou MP et al. | Biological role of hepoxilins: upregulation of phospholipid hydroperoxide glutathione peroxidase as a cellular response to oxidative stress? | 2007 Oct-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17997296 |
Hurley BP et al. | Adhesion molecules involved in hepoxilin A3-mediated neutrophil transepithelial migration. | 2008 | Clin. Exp. Immunol. | pmid:18005361 |
Mumy KL et al. | Distinct isoforms of phospholipase A2 mediate the ability of Salmonella enterica serotype typhimurium and Shigella flexneri to induce the transepithelial migration of neutrophils. | 2008 | Infect. Immun. | pmid:18505810 |
Lin Z et al. | Hepoxilin A3 induces heat shock protein (HSP72) expression in human neutrophils. | 1991 | Biochem. Biophys. Res. Commun. | pmid:1883378 |
Pazos M et al. | Multidrug resistance-associated transporter 2 regulates mucosal inflammation by facilitating the synthesis of hepoxilin A3. | 2008 | J. Immunol. | pmid:19017997 |
Piomelli D | Metabolism of arachidonic acid in nervous system of marine mollusk Aplysia californica. | 1991 | Am. J. Physiol. | pmid:1903603 |
Mumy KL and McCormick BA | The role of neutrophils in the event of intestinal inflammation. | 2009 | Curr Opin Pharmacol | pmid:19854677 |