| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Diseases | D008171 | 37 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
Total
2
Hxa3
Hxa3 is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 289 references associated with Hxa3 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Hxa3
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Hxa3
PubChem Biomolecular Interactions and Pathways
All references with Hxa3
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Douda DN et al. | A lipid mediator hepoxilin A3 is a natural inducer of neutrophil extracellular traps in human neutrophils. | 2015 | Mediators Inflamm. | pmid:25784781 |
| Pazos MA et al. | Distinct cellular sources of hepoxilin A3 and leukotriene B4 are used to coordinate bacterial-induced neutrophil transepithelial migration. | 2015 | J. Immunol. | pmid:25548217 |
| Bou Ghanem EN et al. | The α-tocopherol form of vitamin E reverses age-associated susceptibility to streptococcus pneumoniae lung infection by modulating pulmonary neutrophil recruitment. | 2015 | J. Immunol. | pmid:25512603 |
| Kubala SA et al. | Pathogen induced chemo-attractant hepoxilin A3 drives neutrophils, but not eosinophils across epithelial barriers. | 2014 | Prostaglandins Other Lipid Mediat. | pmid:24315875 |
| Stenson WF | The universe of arachidonic acid metabolites in inflammatory bowel disease: can we tell the good from the bad? | 2014 | Curr. Opin. Gastroenterol. | pmid:24837228 |
| Bhowmick R et al. | Systemic disease during Streptococcus pneumoniae acute lung infection requires 12-lipoxygenase-dependent inflammation. | 2013 | J. Immunol. | pmid:24089193 |
| Gregus AM et al. | Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22493235 |
| Tamang DL et al. | Hepoxilin A(3) facilitates neutrophilic breach of lipoxygenase-expressing airway epithelial barriers. | 2012 | J. Immunol. | pmid:23045615 |
| Hurley BP et al. | Selective eicosanoid-generating capacity of cytoplasmic phospholipase A2 in Pseudomonas aeruginosa-infected epithelial cells. | 2011 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:21097525 |
| Zafiriou MP et al. | Hepoxilin A(3) protects β-cells from apoptosis in contrast to its precursor, 12-hydroperoxyeicosatetraenoic acid. | 2011 | Biochim. Biophys. Acta | pmid:21420506 |
| Cronin A et al. | Mammalian soluble epoxide hydrolase is identical to liver hepoxilin hydrolase. | 2011 | J. Lipid Res. | pmid:21217101 |
| Mumy KL and McCormick BA | The role of neutrophils in the event of intestinal inflammation. | 2009 | Curr Opin Pharmacol | pmid:19854677 |
| Mumy KL et al. | Distinct isoforms of phospholipase A2 mediate the ability of Salmonella enterica serotype typhimurium and Shigella flexneri to induce the transepithelial migration of neutrophils. | 2008 | Infect. Immun. | pmid:18505810 |
| Pazos M et al. | Multidrug resistance-associated transporter 2 regulates mucosal inflammation by facilitating the synthesis of hepoxilin A3. | 2008 | J. Immunol. | pmid:19017997 |
| Hurley BP et al. | Adhesion molecules involved in hepoxilin A3-mediated neutrophil transepithelial migration. | 2008 | Clin. Exp. Immunol. | pmid:18005361 |
| Zafiriou MP et al. | Biological role of hepoxilins: upregulation of phospholipid hydroperoxide glutathione peroxidase as a cellular response to oxidative stress? | 2007 Oct-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17997296 |
| McCormick BA | Bacterial-induced hepoxilin A3 secretion as a pro-inflammatory mediator. | 2007 | FEBS J. | pmid:17608718 |
| Yu Z et al. | Epidermal lipoxygenase products of the hepoxilin pathway selectively activate the nuclear receptor PPARalpha. | 2007 | Lipids | pmid:17436029 |
| Pace-Asciak CR et al. | Hepoxilin analogs, potential new therapeutics in disease. | 2006 | Curr. Pharm. Des. | pmid:16533163 |
| Hurley BP et al. | Involvement of phospholipase A2 in Pseudomonas aeruginosa-mediated PMN transepithelial migration. | 2006 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:16272174 |