| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Diseases | D008171 | 37 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
Total
2
Hxa3
Hxa3 is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 289 references associated with Hxa3 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Hxa3
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Hxa3
PubChem Biomolecular Interactions and Pathways
All references with Hxa3
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nigam S et al. | Receptor-mediated action of hepoxilin A3 releases diacylglycerol and arachidonic acid from human neutrophils. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2171511 |
| Zafiriou MP et al. | Hepoxilin A(3) protects β-cells from apoptosis in contrast to its precursor, 12-hydroperoxyeicosatetraenoic acid. | 2011 | Biochim. Biophys. Acta | pmid:21420506 |
| Cronin A et al. | Mammalian soluble epoxide hydrolase is identical to liver hepoxilin hydrolase. | 2011 | J. Lipid Res. | pmid:21217101 |
| Hurley BP et al. | Selective eicosanoid-generating capacity of cytoplasmic phospholipase A2 in Pseudomonas aeruginosa-infected epithelial cells. | 2011 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:21097525 |
| Dho S et al. | Hepoxilin A3 induces changes in cytosolic calcium, intracellular pH and membrane potential in human neutrophils. | 1990 | Biochem. J. | pmid:2106877 |
| Mumy KL and McCormick BA | The role of neutrophils in the event of intestinal inflammation. | 2009 | Curr Opin Pharmacol | pmid:19854677 |
| Piomelli D | Metabolism of arachidonic acid in nervous system of marine mollusk Aplysia californica. | 1991 | Am. J. Physiol. | pmid:1903603 |
| Pazos M et al. | Multidrug resistance-associated transporter 2 regulates mucosal inflammation by facilitating the synthesis of hepoxilin A3. | 2008 | J. Immunol. | pmid:19017997 |
| Lin Z et al. | Hepoxilin A3 induces heat shock protein (HSP72) expression in human neutrophils. | 1991 | Biochem. Biophys. Res. Commun. | pmid:1883378 |
| Mumy KL et al. | Distinct isoforms of phospholipase A2 mediate the ability of Salmonella enterica serotype typhimurium and Shigella flexneri to induce the transepithelial migration of neutrophils. | 2008 | Infect. Immun. | pmid:18505810 |
| Hurley BP et al. | Adhesion molecules involved in hepoxilin A3-mediated neutrophil transepithelial migration. | 2008 | Clin. Exp. Immunol. | pmid:18005361 |
| Zafiriou MP et al. | Biological role of hepoxilins: upregulation of phospholipid hydroperoxide glutathione peroxidase as a cellular response to oxidative stress? | 2007 Oct-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17997296 |
| McCormick BA | Bacterial-induced hepoxilin A3 secretion as a pro-inflammatory mediator. | 2007 | FEBS J. | pmid:17608718 |
| Yu Z et al. | Epidermal lipoxygenase products of the hepoxilin pathway selectively activate the nuclear receptor PPARalpha. | 2007 | Lipids | pmid:17436029 |
| Laneuville O et al. | Hepoxilin A3 (HxA3) is formed by the rat aorta and is metabolized into HxA3-C, a glutathione conjugate. | 1991 | Biochim. Biophys. Acta | pmid:1675872 |
| Pace-Asciak CR et al. | Hepoxilin analogs, potential new therapeutics in disease. | 2006 | Curr. Pharm. Des. | pmid:16533163 |
| Hurley BP et al. | Involvement of phospholipase A2 in Pseudomonas aeruginosa-mediated PMN transepithelial migration. | 2006 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:16272174 |
| Nigam S and Zafiriou MP | Hepoxilin A3 synthase. | 2005 | Biochem. Biophys. Res. Commun. | pmid:16198304 |
| Laneuville O et al. | Hepoxilins sensitize blood vessels to noradrenaline--stereospecificity of action. | 1992 | Br. J. Pharmacol. | pmid:1559126 |
| Hurley BP et al. | Polymorphonuclear cell transmigration induced by Pseudomonas aeruginosa requires the eicosanoid hepoxilin A3. | 2004 | J. Immunol. | pmid:15494523 |