Hxa3

Hxa3 is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 289 references associated with Hxa3 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Hxa3

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Hxa3

MeSH term MeSH ID Detail
Lung Diseases D008171 37 associated lipids
Inflammation D007249 119 associated lipids
Total 2

PubChem Biomolecular Interactions and Pathways

All references with Hxa3

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Authors Title Published Journal PubMed Link
Piomelli D et al. Formation and action of 8-hydroxy-11,12-epoxy-5,9,14-icosatrienoic acid in Aplysia: a possible second messenger in neurons. 1989 Proc. Natl. Acad. Sci. U.S.A. pmid:2493649
Gregus AM et al. Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22493235
Mrsny RJ et al. Identification of hepoxilin A3 in inflammatory events: a required role in neutrophil migration across intestinal epithelia. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:15123795
Zafiriou MP et al. Biological role of hepoxilins: upregulation of phospholipid hydroperoxide glutathione peroxidase as a cellular response to oxidative stress? 2007 Oct-Nov Prostaglandins Leukot. Essent. Fatty Acids pmid:17997296
Kubala SA et al. Pathogen induced chemo-attractant hepoxilin A3 drives neutrophils, but not eosinophils across epithelial barriers. 2014 Prostaglandins Other Lipid Mediat. pmid:24315875

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