hypericin
hypericin is a lipid of Polyketides (PK) class. Hypericin is associated with abnormalities such as Dermatitis, Phototoxic, Dehydration, Photosensitization, Morphologically altered structure and Myocardial Infarction. The involved functions are known as Cell Cycle Checkpoints, Apoptosis, Acetylation, Cell Survival and Caspase Activation. Hypericin often locates in insoluble fraction, Cytoplasmic matrix, Protoplasm, Tissue membrane and Cytoplasm. The associated genes with hypericin are CDC37 gene, HSPA8 gene, RAF1 gene, cyclin H and FK228. The related lipids are Phosphatidylserines.
Cross Reference
Introduction
To understand associated biological information of hypericin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with hypericin?
hypericin is suspected in Dermatitis, Phototoxic, Photosensitization, Pneumonia, Psoriasis, Phototoxicity, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with hypericin
PubChem Associated disorders and diseases
What pathways are associated with hypericin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with hypericin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with hypericin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with hypericin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with hypericin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with hypericin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with hypericin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Misuth M et al. | Estimation of PKCδ autophosphorylation in U87 MG glioma cells: combination of experimental, conceptual and numerical approaches. | 2017 | J Biophotonics | pmid:27158772 |
| Misuth M et al. | Synergism between PKCδ regulators hypericin and rottlerin enhances apoptosis in U87 MG glioma cells after light stimulation. | 2017 | Photodiagnosis Photodyn Ther | pmid:28373118 |
| Halaburková A et al. | Histone deacetylase inhibitors potentiate photodynamic therapy in colon cancer cells marked by chromatin-mediated epigenetic regulation of . | 2017 | Clin Epigenetics | pmid:28603560 |
| Moritz MNO et al. | Phototoxicity in a laryngeal cancer cell line enhanced by a targeting amphiphilic chlorin photosensitizer. | 2017 | Photodiagnosis Photodyn Ther | pmid:28716739 |
| Borghi-Pangoni FB et al. | Preparation and characterization of bioadhesive system containing hypericin for local photodynamic therapy. | 2017 | Photodiagnosis Photodyn Ther | pmid:28669792 |
| Chen E et al. | One-pot method to prepare a theranostic nanosystem with magnetic resonance imaging function and anticancer activity through multiple mechanisms. | 2017 | Dalton Trans | pmid:28280824 |
| Gattuso H et al. | Deciphering the photosensitization mechanisms of hypericin towards biological membranes. | 2017 | Phys Chem Chem Phys | pmid:28820528 |
| Mühleisen L et al. | Analysis of Hypericin-Mediated Effects and Implications for Targeted Photodynamic Therapy. | 2017 | Int J Mol Sci | pmid:28661430 |
| Duan X et al. | Radioiodinated hypericin disulfonic acid sodium salts as a DNA-binding probe for early imaging of necrotic myocardium. | 2017 | Eur J Pharm Biopharm | pmid:28414189 |
| Zeliou K et al. | Optimized and Validated HPLC Analysis of St. John's Wort Extract and Final Products by Simultaneous Determination of Major Ingredients. | 2017 | J Chromatogr Sci | pmid:28472287 |