hypericin
hypericin is a lipid of Polyketides (PK) class. Hypericin is associated with abnormalities such as Dermatitis, Phototoxic, Dehydration, Photosensitization, Morphologically altered structure and Myocardial Infarction. The involved functions are known as Cell Cycle Checkpoints, Apoptosis, Acetylation, Cell Survival and Caspase Activation. Hypericin often locates in insoluble fraction, Cytoplasmic matrix, Protoplasm, Tissue membrane and Cytoplasm. The associated genes with hypericin are CDC37 gene, HSPA8 gene, RAF1 gene, cyclin H and FK228. The related lipids are Phosphatidylserines.
Cross Reference
Introduction
To understand associated biological information of hypericin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with hypericin?
hypericin is suspected in Dermatitis, Phototoxic, Photosensitization, Pneumonia, Psoriasis, Phototoxicity, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with hypericin
PubChem Associated disorders and diseases
What pathways are associated with hypericin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with hypericin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with hypericin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with hypericin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with hypericin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with hypericin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with hypericin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Huck CW et al. | Comparative analysis of naphthodianthrone and phloroglucine derivatives in St. John's Wort extracts by near infrared spectroscopy, high-performance liquid chromatography and capillary electrophoresis. | 2006 | Anal. Chim. Acta | pmid:17723777 |
| Tatsis EC et al. | 1H NMR determination of hypericin and pseudohypericin in complex natural mixtures by the use of strongly deshielded OH groups. | 2008 | Anal. Chim. Acta | pmid:18190811 |
| Lavie G et al. | Anti-angiogenic activities of hypericin in vivo: potential for ophthalmologic applications. | 2005 | Angiogenesis | pmid:16132616 |
| Olivo M et al. | New frontier in hypericin-mediated diagnosis of cancer with current optical technologies. | 2012 | Ann Biomed Eng | pmid:22124793 |
| Fornaro M et al. | Medicine and psychiatry in Western culture: Ancient Greek myths and modern prejudices. | 2009 | Ann Gen Psychiatry | pmid:19811642 |
| Morgan AJ and Jorm AF | Self-help interventions for depressive disorders and depressive symptoms: a systematic review. | 2008 | Ann Gen Psychiatry | pmid:18710579 |
| Girzu-Amblard M et al. | [Flavonoid and dianthranoid levels of the St.-John's-wort flowering tops]. | 2000 | Ann Pharm Fr | pmid:11060411 |
| Soelberg J et al. | Hyperforin accumulates in the translucent glands of Hypericum perforatum. | 2007 | Ann. Bot. | pmid:17468113 |
| Zobayed SM et al. | Plant-environment interactions: Accumulation of hypericin in dark glands of Hypericum perforatum. | 2006 | Ann. Bot. | pmid:16891333 |
| Gulick RM et al. | Phase I studies of hypericin, the active compound in St. John's Wort, as an antiretroviral agent in HIV-infected adults. AIDS Clinical Trials Group Protocols 150 and 258. | 1999 | Ann. Intern. Med. | pmid:10075619 |