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Hypericin uptake: a prognostic marker for survival in high-grade glioma. |
2008 |
J Clin Neurosci |
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Giganti A et al. |
Murine and human autotaxin alpha, beta, and gamma isoforms: gene organization, tissue distribution, and biochemical characterization. |
2008 |
J. Biol. Chem. |
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Galati EM et al. |
Antiinflammatory and antioxidant activity of Hypericum rumeliacum Boiss. subsp. apollinis (Boiss. & Heldr.) Robson & Strid methanol extract. |
2008 |
Phytother Res |
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Li S et al. |
Chemical markers for the quality control of herbal medicines: an overview. |
2008 |
Chin Med |
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Fernandes H et al. |
Crystallization and preliminary crystallographic studies of Hyp-1, a St John's wort protein implicated in the biosynthesis of hypericin. |
2008 |
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. |
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Kubin A et al. |
How to make hypericin water-soluble. |
2008 |
Pharmazie |
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Bhuvaneswari R et al. |
Molecular profiling of angiogenesis in hypericin mediated photodynamic therapy. |
2008 |
Mol. Cancer |
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Saw CL et al. |
Potentiation of the photodynamic action of hypericin. |
2008 |
J. Environ. Pathol. Toxicol. Oncol. |
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Signal interaction between nitric oxide and hydrogen peroxide in heat shock-induced hypericin production of Hypericum perforatum suspension cells. |
2008 |
Sci. China, C, Life Sci. |
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Kleban J et al. |
Mechanisms involved in the cell cycle and apoptosis of HT-29 cells pre-treated with MK-886 prior to photodynamic therapy with hypericin. |
2008 |
J. Photochem. Photobiol. B, Biol. |
pmid:18771933
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Bertoli A et al. |
Bioactive constituent production in St. John's Wort in vitro hairy roots. Regenerated plant lines. |
2008 |
J. Agric. Food Chem. |
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Sgarbossa A et al. |
In vitro perturbation of aggregation processes in beta-amyloid peptides: a spectroscopic study. |
2008 |
FEBS Lett. |
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Theodossiou TA et al. |
Molecular modeling and experimental evidence for hypericin as a substrate for mitochondrial complex III; mitochondrial photodamage as demonstrated using specific inhibitors. |
2008 |
Free Radic. Biol. Med. |
pmid:18852042
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Seitz G et al. |
In vitro photodynamic therapy in pediatric epithelial liver tumors promoted by hypericin. |
2008 |
Oncol. Rep. |
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Fonge H et al. |
Non-invasive detection and quantification of acute myocardial infarction in rabbits using mono-[123I]iodohypericin microSPECT. |
2008 |
Eur. Heart J. |
pmid:18156139
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Xenophontos M et al. |
Influence of the habitat altitude on the (proto)hypericin and (proto)pseudohypericin levels of hypericum plants from Crete. |
2008 |
Planta Med. |
pmid:18671196
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Minnes R et al. |
The effect of solution electrolytes on the uptake of photosensitizers by liposomal membranes: a salting-out effect. |
2008 |
Chem. Phys. Lipids |
pmid:18606157
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Moulharat N et al. |
Molecular pharmacology of adipocyte-secreted autotaxin. |
2008 |
Chem. Biol. Interact. |
pmid:18282564
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Jocham D et al. |
Photodynamic diagnosis in urology: state-of-the-art. |
2008 |
Eur. Urol. |
pmid:18096307
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Van de Putte M et al. |
Hypericin as a marker for determination of tissue viability after intratumoral ethanol injection in a murine liver tumor model. |
2008 |
Acad Radiol |
pmid:18078913
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Boiy A et al. |
Photosensitizing activity of hypericin and hypericin acetate after topical application on normal mouse skin. |
2008 |
Br. J. Dermatol. |
pmid:18047507
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Menegazzi M et al. |
Protective effects of St. John's wort extract and its component hyperforin against cytokine-induced cytotoxicity in a pancreatic beta-cell line. |
2008 |
Int. J. Biochem. Cell Biol. |
pmid:18226577
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Cole CD et al. |
Hypericin-mediated photodynamic therapy of pituitary tumors: preclinical study in a GH4C1 rat tumor model. |
2008 |
J. Neurooncol. |
pmid:18228116
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Tatsis EC et al. |
1H NMR determination of hypericin and pseudohypericin in complex natural mixtures by the use of strongly deshielded OH groups. |
2008 |
Anal. Chim. Acta |
pmid:18190811
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Kusari S et al. |
An endophytic fungus from Hypericum perforatum that produces hypericin. |
2008 |
J. Nat. Prod. |
pmid:18220354
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Solár P et al. |
Erythropoietin inhibits apoptosis induced by photodynamic therapy in ovarian cancer cells. |
2008 |
Mol. Cancer Ther. |
pmid:18687658
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Clauson KA et al. |
Clinically relevant safety issues associated with St. John's wort product labels. |
2008 |
BMC Complement Altern Med |
pmid:18637192
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Weber W et al. |
Hypericum perforatum (St John's wort) for attention-deficit/hyperactivity disorder in children and adolescents: a randomized controlled trial. |
2008 |
JAMA |
pmid:18544723
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Robe A et al. |
Quantum dots in axillary lymph node mapping: biodistribution study in healthy mice. |
2008 |
BMC Cancer |
pmid:18430208
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Hird AE et al. |
Radiation recall dermatitis: case report and review of the literature. |
2008 |
Curr Oncol |
pmid:18317586
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Lin TH et al. |
Berberine enhances inhibition of glioma tumor cell migration and invasiveness mediated by arsenic trioxide. |
2008 |
BMC Cancer |
pmid:18294404
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Franklin G et al. |
Hypericum perforatum plant cells reduce Agrobacterium viability during co-cultivation. |
2008 |
Planta |
pmid:18247048
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Davids LM et al. |
Hypericin phototoxicity induces different modes of cell death in melanoma and human skin cells. |
2008 |
J. Photochem. Photobiol. B, Biol. |
pmid:18342534
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Kleban J et al. |
Modulation of hypericin photodynamic therapy by pretreatment with 12 various inhibitors of arachidonic acid metabolism in colon adenocarcinoma HT-29 cells. |
2007 Sep-Oct |
Photochem. Photobiol. |
pmid:17880512
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Wielgus AR et al. |
Phototoxicity in human retinal pigment epithelial cells promoted by hypericin, a component of St. John's wort. |
2007 May-Jun |
Photochem. Photobiol. |
pmid:17576381
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Fonge H et al. |
Evaluation of tumor affinity of mono-[(123)I]iodohypericin and mono-[(123)I]iodoprotohypericin in a mouse model with a RIF-1 tumor. |
2007 May-Jun |
Contrast Media Mol Imaging |
pmid:17546702
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Rückert U et al. |
Simultaneous determination of total hypericin and hyperforin in St. John's wort extracts by HPLC with electrochemical detection. |
2007 May-Jun |
Phytochem Anal |
pmid:17500362
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Kabingu E et al. |
CD8+ T cell-mediated control of distant tumours following local photodynamic therapy is independent of CD4+ T cells and dependent on natural killer cells. |
2007 |
Br. J. Cancer |
pmid:17505510
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Böer U et al. |
CRE/CREB-driven up-regulation of gene expression by chronic social stress in CRE-luciferase transgenic mice: reversal by antidepressant treatment. |
2007 |
PLoS ONE |
pmid:17487276
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Soelberg J et al. |
Hyperforin accumulates in the translucent glands of Hypericum perforatum. |
2007 |
Ann. Bot. |
pmid:17468113
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Chung DJ et al. |
Black cohosh and St. John's wort (GYNO-Plus) for climacteric symptoms. |
2007 |
Yonsei Med. J. |
pmid:17461529
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Kosuth J et al. |
Expression of the hyp-1 gene in early stages of development of Hypericum perforatum L. |
2007 |
Plant Cell Rep. |
pmid:16988829
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Koperdáková J et al. |
Variation in the content of hypericins in four generations of seed progeny of Hypericum perforatum somaclones. |
2007 |
J. Plant Res. |
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Savikin K et al. |
Antiinflammatory activity of ethanol extracts of Hypericum perforatum L., H. barbatum Jacq., H. hirsutum L., H. richeri Vill. and H. androsaemum L. in rats. |
2007 |
Phytother Res |
pmid:17143926
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Bobrov N et al. |
Histomorphological changes in murine fibrosarcoma after hypericin-based photodynamic therapy. |
2007 |
Phytomedicine |
pmid:17095201
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Saw CL et al. |
Superiority of N-methyl pyrrolidone over albumin with hypericin for fluorescence diagnosis of human bladder cancer cells implanted in the chick chorioallantoic membrane model. |
2007 |
J. Photochem. Photobiol. B, Biol. |
pmid:17134910
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Kocanova S et al. |
Induction of heme-oxygenase 1 requires the p38MAPK and PI3K pathways and suppresses apoptotic cell death following hypericin-mediated photodynamic therapy. |
2007 |
Apoptosis |
pmid:17219054
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Coenye T et al. |
In vitro inhibition of Streptococcus mutans biofilm formation on hydroxyapatite by subinhibitory concentrations of anthraquinones. |
2007 |
Antimicrob. Agents Chemother. |
pmid:17220400
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Crnolatac I et al. |
In vitro accumulation and permeation of hypericin and lipophilic analogues in 2-D and 3-D cellular systems. |
2007 |
Int. J. Oncol. |
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Ung CY et al. |
In silico prediction of pregnane X receptor activators by machine learning approaches. |
2007 |
Mol. Pharmacol. |
pmid:17003167
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Hu ZP et al. |
A mechanistic study on altered pharmacokinetics of irinotecan by St. John's wort. |
2007 |
Curr. Drug Metab. |
pmid:17305494
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Galabov AS |
Virucidal agents in the eve of manorapid synergy. |
2007 |
GMS Krankenhhyg Interdiszip |
pmid:20200679
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Lans C et al. |
Ethnoveterinary medicines used for ruminants in British Columbia, Canada. |
2007 |
J Ethnobiol Ethnomed |
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Wang Y et al. |
Cellular pharmacological properties of gold(III) porphyrin 1a, a potential anticancer drug lead. |
2007 |
Eur. J. Pharmacol. |
pmid:17116302
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Babić D |
Herbal medicine in the treatment of mental disorders. |
2007 |
Psychiatr Danub |
pmid:17914328
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Xenophontos M et al. |
Influence of the developmental stage on the (proto)-hypericin and (proto)pseudohypericin levels of Hypericum plants from Crete. |
2007 |
Planta Med. |
pmid:17893828
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Boiy A et al. |
Influence of application and formulation factors on the penetration of hypericin in normal mouse skin and UV induced skin tumors. |
2007 |
J. Photochem. Photobiol. B, Biol. |
pmid:17983765
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Sauviat MP et al. |
Hypericin activates L-type Ca2+ channels in cardiac myocytes. |
2007 |
J. Nat. Prod. |
pmid:17291039
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Kornfeld A et al. |
The production of hypericins in two selected Hypericum perforatum shoot cultures is related to differences in black gland structure. |
2007 |
Plant Physiol. Biochem. |
pmid:17300946
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Song X et al. |
[The development of secondary cells in the callus of Hypericum perforatum L. and hypericins accumulation]. |
2007 |
Fen Zi Xi Bao Sheng Wu Xue Bao |
pmid:17357449
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Du HY et al. |
Hypericin photoactivation triggers down-regulation of matrix metalloproteinase-9 expression in well-differentiated human nasopharyngeal cancer cells. |
2007 |
Cell. Mol. Life Sci. |
pmid:17385073
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Laggner H et al. |
The main components of St John's Wort inhibit low-density lipoprotein atherogenic modification: a beneficial "side effect" of an OTC antidepressant drug? |
2007 |
Free Radic. Res. |
pmid:17364950
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Gödtel-Armbrust U et al. |
Variability in PXR-mediated induction of CYP3A4 by commercial preparations and dry extracts of St. John's wort. |
2007 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:17593354
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Saczko J et al. |
Cytosolic superoxide dismutase activity after photodynamic therapy, intracellular distribution of Photofrin II and hypericin, and P-glycoprotein localization in human colon adenocarcinoma. |
2007 |
Folia Histochem. Cytobiol. |
pmid:17597022
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PavlÃk M et al. |
Hypericin and hyperforin production in St. John's wort in vitro culture: influence of saccharose, polyethylene glycol, methyl jasmonate, and Agrobacterium tumefaciens. |
2007 |
J. Agric. Food Chem. |
pmid:17608493
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Sosa S et al. |
Topical anti-inflammatory activity of extracts and compounds from Hypericum perforatum L. |
2007 |
J. Pharm. Pharmacol. |
pmid:17524236
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Seitz G et al. |
In vitro photodynamic therapy of childhood rhabdomyosarcoma. |
2007 |
Int. J. Oncol. |
pmid:17273762
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Ritz R et al. |
Photodynamic therapy of malignant glioma with hypericin: comprehensive in vitro study in human glioblastoma cell lines. |
2007 |
Int. J. Oncol. |
pmid:17273767
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Cecchini C et al. |
Antimicrobial activity of seven hypericum entities from central Italy. |
2007 |
Planta Med. |
pmid:17516331
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[Morphological identification of 20 medicinal species in Hypericum]. |
2007 |
Zhongguo Zhong Yao Za Zhi |
pmid:17655138
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Mikes J et al. |
Necrosis predominates in the cell death of human colon adenocarcinoma HT-29 cells treated under variable conditions of photodynamic therapy with hypericin. |
2007 |
Photochem. Photobiol. Sci. |
pmid:17609769
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Dasgupta A et al. |
Drug-herb interaction: effect of St John's wort on bioavailability and metabolism of procainamide in mice. |
2007 |
Arch. Pathol. Lab. Med. |
pmid:17616997
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Vacek J et al. |
[Hypericin and hyperforin: bioactive components of St. John's Wort (Hypericum perforatum). Their isolation, analysis and study of physiological effect]. |
2007 |
Ceska Slov Farm |
pmid:17619301
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Adigbli DK et al. |
Photochemical internalisation of chemotherapy potentiates killing of multidrug-resistant breast and bladder cancer cells. |
2007 |
Br. J. Cancer |
pmid:17667930
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Fu CY et al. |
Fluorescence detection of bladder cancer using urine cytology. |
2007 |
Int. J. Oncol. |
pmid:17671678
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Bhuvaneswari R et al. |
Hypericin-mediated photodynamic therapy in combination with Avastin (bevacizumab) improves tumor response by downregulating angiogenic proteins. |
2007 |
Photochem. Photobiol. Sci. |
pmid:18046482
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Bhuvaneswari R et al. |
Effect of hypericin-mediated photodynamic therapy on the expression of vascular endothelial growth factor in human nasopharyngeal carcinoma. |
2007 |
Int. J. Mol. Med. |
pmid:17786271
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Huygens A et al. |
Influence of the glycosaminoglycan layer on the permeation of hypericin in rat bladders in vivo. |
2007 |
BJU Int. |
pmid:17868424
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Saw CL et al. |
Effects of N-methyl pyrrolidone on the uptake of hypericin in human bladder carcinoma and co-staining with DAPI investigated by confocal microscopy. |
2007 |
Technol. Cancer Res. Treat. |
pmid:17877426
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Schmidbauer J and Marberger M |
Recent developments in fluorescence cystoscopy: do novel agents bring a benefit? |
2007 |
Curr Opin Urol |
pmid:17762629
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Butterweck V and Schmidt M |
St. John's wort: role of active compounds for its mechanism of action and efficacy. |
2007 |
Wien Med Wochenschr |
pmid:17704987
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Calapai G and Caputi AP |
Herbal medicines: can we do without pharmacologist? |
2007 |
Evid Based Complement Alternat Med |
pmid:18227932
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Bletter N |
A quantitative synthesis of the medicinal ethnobotany of the Malinké of Mali and the Asháninka of Peru, with a new theoretical framework. |
2007 |
J Ethnobiol Ethnomed |
pmid:18053260
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Sacková V et al. |
Hypericin-induced photocytotoxicity is connected with G2/M arrest in HT-29 and S-phase arrest in U937 cells. |
2006 Sep-Oct |
Photochem. Photobiol. |
pmid:16740057
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Vardapetian GR et al. |
[The influence of some elicitors on growth and morphogenesis of Hypericum perforatum callus cultures]. |
2006 Nov-Dec |
Ontogenez |
pmid:17168377
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Kocanova S et al. |
Characterization of the interaction of hypericin with protein kinase C in U-87 MG human glioma cells. |
2006 May-Jun |
Photochem. Photobiol. |
pmid:16396605
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Rückert U et al. |
A high-performance liquid chromatography with electrochemical detection for the determination of total hypericin in extracts of St. John's Wort. |
2006 May-Jun |
Phytochem Anal |
pmid:16749423
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Schipper ML et al. |
Evaluation of firefly luciferase bioluminescence mediated photodynamic toxicity in cancer cells. |
2006 Jul-Aug |
Mol Imaging Biol |
pmid:16791748
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Sobaci G et al. |
Hypericin-enhanced argon laser photocoagulation for subfoveal choroidal neovascular membrane in age-related macular degeneration: a pilot study. |
2006 Jan-Feb |
Eur J Ophthalmol |
pmid:16496255
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Kasper S et al. |
Superior efficacy of St John's wort extract WS 5570 compared to placebo in patients with major depression: a randomized, double-blind, placebo-controlled, multi-center trial [ISRCTN77277298]. |
2006 |
BMC Med |
pmid:16796730
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Grimm T et al. |
Single and multiple dose pharmacokinetics of maritime pine bark extract (pycnogenol) after oral administration to healthy volunteers. |
2006 |
BMC Clin Pharmacol |
pmid:16887024
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Skalkos D et al. |
Photophysical properties of Hypericum perforatum L. extracts--novel photosensitizers for PDT. |
2006 |
J. Photochem. Photobiol. B, Biol. |
pmid:16388961
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Laptev R et al. |
Intracellular chemiluminescence activates targeted photodynamic destruction of leukaemic cells. |
2006 |
Br. J. Cancer |
pmid:16819545
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Zeisser-Labouèbe M et al. |
Hypericin-loaded nanoparticles for the photodynamic treatment of ovarian cancer. |
2006 |
Int J Pharm |
pmid:16930882
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Berlanda J et al. |
Characterization of apoptosis induced by photodynamic treatment with hypericin in A431 human epidermoid carcinoma cells. |
2006 |
J. Environ. Pathol. Toxicol. Oncol. |
pmid:16566716
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Schulz HU et al. |
Investigation of the effect on photosensitivity following multiple oral dosing of two different hypericum extracts in healthy men. |
2006 |
Arzneimittelforschung |
pmid:16618014
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Mukherjee P et al. |
Maristentorin, a novel pigment from the positively phototactic marine ciliate Maristentor dinoferus, is structurally related to hypericin and stentorin. |
2006 |
J Phys Chem B |
pmid:16553454
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Williams FB et al. |
Development and evaluation of methods for determination of naphthodianthrones and flavonoids in St. John's wort. |
2006 |
J Chromatogr A |
pmid:16554056
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Randløv C et al. |
The efficacy of St. John's Wort in patients with minor depressive symptoms or dysthymia--a double-blind placebo-controlled study. |
2006 |
Phytomedicine |
pmid:16423519
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Mueller SC et al. |
The extent of induction of CYP3A by St. John's wort varies among products and is linked to hyperforin dose. |
2006 |
Eur. J. Clin. Pharmacol. |
pmid:16341856
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