| MeSH term | MeSH ID | Detail |
|---|---|---|
| Urinary Bladder, Overactive | D053201 | 2 associated lipids |
| Keratosis, Actinic | D055623 | 3 associated lipids |
| Neoplasms, Radiation-Induced | D009381 | 3 associated lipids |
| Epidermolysis Bullosa | D004820 | 3 associated lipids |
| Radiodermatitis | D011855 | 3 associated lipids |
| Lymphoma, T-Cell, Cutaneous | D016410 | 4 associated lipids |
| Nasopharyngeal Neoplasms | D009303 | 4 associated lipids |
| Choroidal Neovascularization | D020256 | 5 associated lipids |
| Neoplasm Recurrence, Local | D009364 | 5 associated lipids |
| Eye Injuries | D005131 | 7 associated lipids |
hypericin
hypericin is a lipid of Polyketides (PK) class. Hypericin is associated with abnormalities such as Dermatitis, Phototoxic, Dehydration, Photosensitization, Morphologically altered structure and Myocardial Infarction. The involved functions are known as Cell Cycle Checkpoints, Apoptosis, Acetylation, Cell Survival and Caspase Activation. Hypericin often locates in insoluble fraction, Cytoplasmic matrix, Protoplasm, Tissue membrane and Cytoplasm. The associated genes with hypericin are CDC37 gene, HSPA8 gene, RAF1 gene, cyclin H and FK228. The related lipids are Phosphatidylserines.
Cross Reference
Introduction
To understand associated biological information of hypericin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with hypericin?
hypericin is suspected in Dermatitis, Phototoxic, Photosensitization, Pneumonia, Psoriasis, Phototoxicity, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with hypericin
PubChem Associated disorders and diseases
What pathways are associated with hypericin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with hypericin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with hypericin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with hypericin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with hypericin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with hypericin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with hypericin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Montoya A et al. | Development of a novel formulation with hypericin to treat cutaneous leishmaniasis based on photodynamic therapy in in vitro and in vivo studies. | 2015 | Antimicrob. Agents Chemother. | pmid:26169411 |
| Kerb R et al. | Single-dose and steady-state pharmacokinetics of hypericin and pseudohypericin. | 1996 | Antimicrob. Agents Chemother. | pmid:8878586 |
| Farnet CM et al. | Human immunodeficiency virus type 1 cDNA integration: new aromatic hydroxylated inhibitors and studies of the inhibition mechanism. | 1998 | Antimicrob. Agents Chemother. | pmid:9736543 |
| Jacobson JM et al. | Pharmacokinetics, safety, and antiviral effects of hypericin, a derivative of St. John's wort plant, in patients with chronic hepatitis C virus infection. | 2001 | Antimicrob. Agents Chemother. | pmid:11158749 |
| Tang J et al. | Virucidal activity of hypericin against enveloped and non-enveloped DNA and RNA viruses. | 1990 | Antiviral Res. | pmid:1699494 |
| Barnard DL et al. | Evaluation of the antiviral activity of anthraquinones, anthrones and anthraquinone derivatives against human cytomegalovirus. | 1992 | Antiviral Res. | pmid:1310583 |
| Stevenson NR and Lenard J | Antiretroviral activities of hypericin and rose bengal: photodynamic effects on Friend leukemia virus infection of mice. | 1993 | Antiviral Res. | pmid:8338350 |
| Hudson JB et al. | The importance of light in the anti-HIV effect of hypericin. | 1993 | Antiviral Res. | pmid:8460933 |
| Moraleda G et al. | Inhibition of duck hepatitis B virus replication by hypericin. | 1993 | Antiviral Res. | pmid:8470884 |
| Morrey JD et al. | Identification of active antiviral compounds against a New York isolate of West Nile virus. | 2002 | Antiviral Res. | pmid:12076755 |