hypericin

hypericin is a lipid of Polyketides (PK) class. Hypericin is associated with abnormalities such as Dermatitis, Phototoxic, Dehydration, Photosensitization, Morphologically altered structure and Myocardial Infarction. The involved functions are known as Cell Cycle Checkpoints, Apoptosis, Acetylation, Cell Survival and Caspase Activation. Hypericin often locates in insoluble fraction, Cytoplasmic matrix, Protoplasm, Tissue membrane and Cytoplasm. The associated genes with hypericin are CDC37 gene, HSPA8 gene, RAF1 gene, cyclin H and FK228. The related lipids are Phosphatidylserines.

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Introduction

To understand associated biological information of hypericin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with hypericin?

hypericin is suspected in Dermatitis, Phototoxic, Photosensitization, Pneumonia, Psoriasis, Phototoxicity, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with hypericin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uterine Cervical Neoplasms D002583 10 associated lipids
Neoplasms, Experimental D009374 10 associated lipids
Neoplasms, Radiation-Induced D009381 3 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Carcinoma, Squamous Cell D002294 14 associated lipids
Skin Neoplasms D012878 12 associated lipids
Burns D002056 34 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Per page 10 20 50 | Total 38

PubChem Associated disorders and diseases

What pathways are associated with hypericin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with hypericin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with hypericin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with hypericin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with hypericin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with hypericin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with hypericin

Download all related citations
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Authors Title Published Journal PubMed Link
Hao GY and Zhang YH [Fluorescence technique on diagnosis of urinary bladder carcinoma]. 2003 Zhonghua Yi Xue Za Zhi pmid:14723217
Sun YX et al. [Effects of hypericin associated with light irradiation on human laryngeal squamous cell carcinoma strain Hep-2]. 2005 Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:16429734
Chen ML et al. [Determining the quantity of hypericin in medicinal materials and asepsis seedings of Hypericum perforatum by HPLC]. 2003 Zhongguo Zhong Yao Za Zhi pmid:15615403
Xu MS et al. [Effect of factors on callus biomass and synthetic mass of hypericin in Hypericum perforatum]. 2003 Zhongguo Zhong Yao Za Zhi pmid:15620179
Sun DL et al. [Morphological identification of 20 medicinal species in Hypericum]. 2007 Zhongguo Zhong Yao Za Zhi pmid:17655138
Xu MS et al. [Induction of callus of Hypericum perforatum L. and qualitative identification of active constituents of its callus]. 2001 Zhongguo Zhong Yao Za Zhi pmid:12776326
Cai W et al. [Influence of luyoutal on serum cytokines in patients with depression]. 2003 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:14666775
Hao PF et al. [Study on the enzyme extraction process of hypericin by pectinase]. 2011 Zhong Yao Cai pmid:22066412
Alali FQ et al. LC-MS and LC-PDA analysis of Hypericum empetrifolium and Hypericum sinaicum. 2009 Jul-Aug Z. Naturforsch., C, J. Biosci. pmid:19791496
Chung DJ et al. Black cohosh and St. John's wort (GYNO-Plus) for climacteric symptoms. 2007 Yonsei Med. J. pmid:17461529