| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Uterine Cervical Neoplasms | D002583 | 10 associated lipids |
| Neoplasms, Experimental | D009374 | 10 associated lipids |
| Neoplasms, Radiation-Induced | D009381 | 3 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Carcinoma, Squamous Cell | D002294 | 14 associated lipids |
| Skin Neoplasms | D012878 | 12 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
hypericin
hypericin is a lipid of Polyketides (PK) class. Hypericin is associated with abnormalities such as Dermatitis, Phototoxic, Dehydration, Photosensitization, Morphologically altered structure and Myocardial Infarction. The involved functions are known as Cell Cycle Checkpoints, Apoptosis, Acetylation, Cell Survival and Caspase Activation. Hypericin often locates in insoluble fraction, Cytoplasmic matrix, Protoplasm, Tissue membrane and Cytoplasm. The associated genes with hypericin are CDC37 gene, HSPA8 gene, RAF1 gene, cyclin H and FK228. The related lipids are Phosphatidylserines.
Cross Reference
Introduction
To understand associated biological information of hypericin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with hypericin?
hypericin is suspected in Dermatitis, Phototoxic, Photosensitization, Pneumonia, Psoriasis, Phototoxicity, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with hypericin
PubChem Associated disorders and diseases
What pathways are associated with hypericin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with hypericin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with hypericin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with hypericin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with hypericin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with hypericin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with hypericin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chaloupka R et al. | The effect of hypericin and hypocrellin-A on lipid membranes and membrane potential of 3T3 fibroblasts. | 1999 | Biochim. Biophys. Acta | pmid:10209209 |
| Bork PM et al. | Hypericin as a non-antioxidant inhibitor of NF-kappa B. | 1999 | Planta Med. | pmid:10364831 |
| Das K et al. | Photophysics of hypericin and hypocrellin A in complex with subcellular components: interactions with human serum albumin. | 1999 | Photochem. Photobiol. | pmid:10378001 |
| Calapai G et al. | Effects of Hypericum perforatum on levels of 5-hydroxytryptamine, noradrenaline and dopamine in the cortex, diencephalon and brainstem of the rat. | 1999 | J. Pharm. Pharmacol. | pmid:10454050 |
| Franklin M et al. | Neuroendocrine evidence for dopaminergic actions of hypericum extract (LI 160) in healthy volunteers. | 1999 | Biol. Psychiatry | pmid:10459411 |
| Schempp CM et al. | Hypericin levels in human serum and interstitial skin blister fluid after oral single-dose and steady-state administration of Hypericum perforatum extract (St. John's wort). | 1999 Sep-Oct | Skin Pharmacol. Appl. Skin Physiol. | pmid:10461100 |
| Weiner L et al. | Targeted cross-linking of a molten globule form of acetylcholinesterase by the virucidal agent hypericin. | 1999 | Biochemistry | pmid:10471290 |
| Fiebich BL et al. | Antibacterial activity of hyperforin from St John's wort. | 1999 | Lancet | pmid:10475222 |
| Kocisová E et al. | Sequence specific interaction of the photoactive drug hypericin depends on the structural arrangement and the stability of the structure containing its specific 5AG3 target: a resonance Raman spectroscopy study. | 1999 | J. Biomol. Struct. Dyn. | pmid:10496421 |
| Tahara YR et al. | The antidepressant hypericin inhibits progression of experimental proliferative vitreoretinopathy. | 1999 | Curr. Eye Res. | pmid:10520228 |