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St. John's Wort constituents modulate P-glycoprotein transport activity at the blood-brain barrier. |
2010 |
Pharm. Res. |
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Small-animal SPECT and SPECT/CT: application in cardiovascular research. |
2010 |
Eur. J. Nucl. Med. Mol. Imaging |
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Structures, biological activities and phylogenetic relationships of terpenoids from marine ciliates of the genus Euplotes. |
2010 |
Mar Drugs |
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2010 |
J. Nat. Prod. |
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Study of dynamic accumulation of secondary metabolites in three subspecies of Hypericum perforatum. |
2010 |
Fitoterapia |
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Chemical constituents and antidepressant activity of the new species Hypericum enshiense occurring in China. |
2010 |
Phytomedicine |
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Crystal structure of Hyp-1, a St. John's wort protein implicated in the biosynthesis of hypericin. |
2010 |
J. Struct. Biol. |
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The role of cyclooxygenase-2 in cell proliferation and cell death in human malignancies. |
2010 |
Int J Cell Biol |
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Effects of hypericin on the structure and aggregation properties of β-amyloid peptides. |
2010 |
Eur. Biophys. J. |
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Hypericin prolongs action potential duration in hippocampal neurons by acting on K+ channels. |
2010 |
Br. J. Pharmacol. |
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Interaction between hypericin and hemoglobin. |
2010 |
J. Photochem. Photobiol. B, Biol. |
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Inhibition characteristics of hypericin on rat small intestine glutathione-S-transferases. |
2010 |
Chem. Biol. Interact. |
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Comparative in vitro study on the characteristics of different photosensitizers employed in PDT. |
2010 |
J. Photochem. Photobiol. B, Biol. |
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Cellular and molecular mechanisms of photodynamic hypericin therapy for nasopharyngeal carcinoma cells. |
2010 |
J. Pharmacol. Exp. Ther. |
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Effect of St. John's Wort standardized extract and hypericin on in vitro placental calcium transport. |
2010 |
J Med Food |
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Boiy A et al. |
Topical treatment of disseminated superficial actinic porokeratosis with hypericin-photodynamic therapy: a case report. |
2010 |
Photodiagnosis Photodyn Ther |
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Aboukhatwa M et al. |
Antidepressants are a rational complementary therapy for the treatment of Alzheimer's disease. |
2010 |
Mol Neurodegener |
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Optimization of protein extraction from Hypericum perforatum tissues and immunoblotting detection of Hyp-1 at different stages of leaf development. |
2010 |
Mol. Biotechnol. |
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Volak LP and Court MH |
Role for protein kinase C delta in the functional activity of human UGT1A6: implications for drug-drug interactions between PKC inhibitors and UGT1A6. |
2010 |
Xenobiotica |
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Prakash DJ et al. |
Effect of nanohypericum (Hypericum perforatum gold nanoparticles) treatment on restraint stressinduced behavioral and biochemical alteration in male albino mice. |
2010 |
Pharmacognosy Res |
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Bilateral posterior RION after concomitant radiochemotherapy with temozolomide in a patient with glioblastoma multiforme: a case report. |
2010 |
BMC Cancer |
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Naturally occurring food toxins. |
2010 |
Toxins (Basel) |
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TP53 regulates human AlkB homologue 2 expression in glioma resistance to Photofrin-mediated photodynamic therapy. |
2010 |
Br. J. Cancer |
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Kumar A et al. |
Effect of St. John's Wort (Hypericum perforatum) treatment on restraint stress-induced behavioral and biochemical alteration in mice. |
2010 |
BMC Complement Altern Med |
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Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy. |
2010 |
Int J Cell Biol |
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Proliferation of retinal pigment epithelial cells induced by (R,R)-XY-10 and (S,S)-XY-10 and their action mechanisms. |
2010 |
Int J Ophthalmol |
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Importance of novel drug delivery systems in herbal medicines. |
2010 |
Pharmacogn Rev |
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PUFAs enhance oxidative stress and apoptosis in tumour cells exposed to hypericin-mediated PDT. |
2010 |
Photochem. Photobiol. Sci. |
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Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method. |
2010 |
Healthc Inform Res |
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Role of p38 MAPKs in hypericin photodynamic therapy-induced apoptosis of nasopharyngeal carcinoma cells. |
2009 Sep-Oct |
Photochem. Photobiol. |
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Cationic hypericin derivatives as novel agents with photobactericidal activity: synthesis and photodynamic inactivation of Propionibacterium acnes. |
2009 Sep-Oct |
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[Experimental study of vitreoretinal proliferation inhibition by the use of hypericin]. |
2009 Sep-Oct |
Arq Bras Oftalmol |
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The multifaceted photocytotoxic profile of hypericin. |
2009 Nov-Dec |
Mol. Pharm. |
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Time-resolved luminescence and singlet oxygen formation after illumination of the hypericin-low-density lipoprotein complex. |
2009 May-Jun |
Photochem. Photobiol. |
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Fluorescence study on the interaction between hypericin and lens protein "alpha-crystallin". |
2009 Jul-Aug |
Photochem. Photobiol. |
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LC-MS and LC-PDA analysis of Hypericum empetrifolium and Hypericum sinaicum. |
2009 Jul-Aug |
Z. Naturforsch., C, J. Biosci. |
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Study of interaction of hypericin and its pharmaceutical preparation by fluorescence techniques. |
2009 Jan-Feb |
J Biomed Opt |
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Role of protein kinase C in 15-HETE-induced hypoxic pulmonary vasoconstriction. |
2009 Feb-Mar |
Prostaglandins Leukot. Essent. Fatty Acids |
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Bhuvaneswari R et al. |
Targeting EGFR with photodynamic therapy in combination with Erbitux enhances in vivo bladder tumor response. |
2009 |
Mol. Cancer |
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Karioti A et al. |
Rapid and efficient purification of naphthodianthrones from St. John's wort extract by using liquid-liquid extraction and SEC. |
2009 |
J Sep Sci |
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Screening of nanoparticulate delivery systems for the photodetection of cancer in a simple and cost-effective model. |
2009 |
Nanomedicine (Lond) |
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Photodynamic effect of hypericin in primary cultures of human umbilical endothelial cells and glioma cell lines. |
2009 |
Phytother Res |
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Impact of the haplotypes of the human pregnane X receptor gene on the basal and St John's wort-induced activity of cytochrome P450 3A4 enzyme. |
2009 |
Br J Clin Pharmacol |
pmid:19173680
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Molecular imaging of cell death. |
2009 |
Methods |
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Zeisser-Labouèbe M et al. |
Benefits of nanoencapsulation for the hypercin-mediated photodetection of ovarian micrometastases. |
2009 |
Eur J Pharm Biopharm |
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Effects of different concentrations of benzylaminopurine on shoot regeneration and hypericin content in Hypericum triquetrifolium Turra. |
2009 |
Nat. Prod. Res. |
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Ultraviolet light and photosensitising agents activate TRPA1 via generation of oxidative stress. |
2009 |
Cell Calcium |
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Photosensitized production of singlet oxygen: spatially-resolved optical studies in single cells. |
2009 |
Photochem. Photobiol. Sci. |
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The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism. |
2009 |
Nucl Recept Signal |
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Time-resolved gene expression profiling of human squamous cell carcinoma cells during the apoptosis process induced by photodynamic treatment with hypericin. |
2009 |
Int. J. Oncol. |
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Light-independent metabolomics of endophytic Thielavia subthermophila provides insight into microbial hypericin biosynthesis. |
2009 |
J. Nat. Prod. |
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Involvement of serotoninergic 5-HT1A/2A, alpha-adrenergic and dopaminergic D1 receptors in St. John's wort-induced prepulse inhibition deficit: a possible role of hyperforin. |
2009 |
Behav. Brain Res. |
pmid:19136030
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Schneider-Yin X et al. |
Hypericin and 5-aminolevulinic acid-induced protoporphyrin IX induce enhanced phototoxicity in human endometrial cancer cells with non-coherent white light. |
2009 |
Photodiagnosis Photodyn Ther |
pmid:19447367
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In vitro study of the photocytotoxicity of bathochromically-shifted hypericin derivatives. |
2009 |
Photochem. Photobiol. Sci. |
pmid:19492110
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Shibata Y |
Comment on "Hypericin uptake: a prognostic marker for survival in high-grade glioma". |
2009 |
J Clin Neurosci |
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Melanomas display increased cytoprotection to hypericin-mediated cytotoxicity through the induction of autophagy. |
2009 |
Cell Biol. Int. |
pmid:19596456
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Zeisser-Labouèbe M et al. |
Quenching-induced deactivation of photosensitizer by nanoencapsulation to improve phototherapy of cancer. |
2009 |
J Drug Target |
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Nanovesicles released by Dictyostelium cells: a potential carrier for drug delivery. |
2009 |
Int J Pharm |
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Kava and St. John's Wort: current evidence for use in mood and anxiety disorders. |
2009 |
J Altern Complement Med |
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Kusari S et al. |
Positive correlations between hypericin and putative precursors detected in the quantitative secondary metabolite spectrum of Hypericum. |
2009 |
Phytochemistry |
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In vitro anti-neoplastic activity of the ethno-pharmaceutical plant Hypericum adenotrichum Spach endemic to Western Turkey. |
2009 |
Oncol. Rep. |
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The association between self-reported cataracts and St. John's Wort. |
2009 |
Curr. Eye Res. |
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Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells. |
2009 |
Photochem. Photobiol. Sci. |
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The role of p53 in the efficiency of photodynamic therapy with hypericin and subsequent long-term survival of colon cancer cells. |
2009 |
Photochem. Photobiol. Sci. |
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Clinical application of fluorescence endoscopic imaging using hypericin for the diagnosis of human oral cavity lesions. |
2009 |
Br. J. Cancer |
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Matrix-free UV-laser desorption/ionization (LDI) mass spectrometric imaging at the single-cell level: distribution of secondary metabolites of Arabidopsis thaliana and Hypericum species. |
2009 |
Plant J. |
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Identification of light-independent inhibition of human immunodeficiency virus-1 infection through bioguided fractionation of Hypericum perforatum. |
2009 |
Virol. J. |
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Study of active naphtodianthrone St John's Wort compounds by electrospray ionization Fourier transform ion cyclotron resonance and multi-stage mass spectrometry in sustained off-resonance irradiation collision-induced dissociation and infrared multiphoton dissociation modes. |
2009 |
Rapid Commun. Mass Spectrom. |
pmid:19224526
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Lipid-mediated preferential localization of hypericin in lipid membranes. |
2009 |
Biochim. Biophys. Acta |
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Chemical constituents of Hypericum adenotrichum Spach, an endemic Turkish species. |
2009 |
Nat. Prod. Res. |
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Retinal phototoxicity in a novel murine model of intraocular lens implantation. |
2009 |
Mol. Vis. |
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Photodynamic therapy in the therapy for recurrent/persistent nasopharyngeal cancer. |
2009 |
Head Neck Oncol |
pmid:20017928
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Gao Q et al. |
PKC alpha affects cell cycle progression and proliferation in human RPE cells through the downregulation of p27kip1. |
2009 |
Mol. Vis. |
pmid:20011080
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Herb-drug interactions with St John's wort (Hypericum perforatum): an update on clinical observations. |
2009 |
AAPS J |
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Medicine and psychiatry in Western culture: Ancient Greek myths and modern prejudices. |
2009 |
Ann Gen Psychiatry |
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Wright KE et al. |
Peripheral neural cell sensitivity to mTHPC-mediated photodynamic therapy in a 3D in vitro model. |
2009 |
Br. J. Cancer |
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Topic issue on new treatments in bladder cancer. |
2009 |
World J Urol |
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Interactive transport, subcellular relocation and enhanced phototoxicity of hypericin encapsulated in guanidinylated liposomes via molecular recognition. |
2008 Sep-Oct |
Photochem. Photobiol. |
pmid:18627515
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Kah JC et al. |
Endoscopic image analysis of photosensitizer fluorescence as a promising noninvasive approach for pathological grading of bladder cancer in situ. |
2008 Sep-Oct |
J Biomed Opt |
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Fluorescence diagnosis of bladder cancer with new water soluble hypericin bound to polyvinylpyrrolidone: PVP-hypericin. |
2008 Nov-Dec |
Photochem. Photobiol. |
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Kacerovská D et al. |
Photodynamic therapy of nonmelanoma skin cancer with topical hypericum perforatum extract--a pilot study. |
2008 May-Jun |
Photochem. Photobiol. |
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Accumulation and interaction of hypericin in low-density lipoprotein--a photophysical study. |
2008 May-Jun |
Photochem. Photobiol. |
pmid:18435618
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Subcellular colocalization of hypericin with respect to endoplasmic reticulum and Golgi apparatus in glioblastoma cells. |
2008 Jul-Aug |
Anticancer Res. |
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Kascakova S et al. |
High level of low-density lipoprotein receptors enhance hypericin uptake by U-87 MG cells in the presence of LDL. |
2008 Jan-Feb |
Photochem. Photobiol. |
pmid:18173711
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Wessels JT et al. |
Photosensitizing and radiosensitizing effects of hypericin on human renal carcinoma cells in vitro. |
2008 Jan-Feb |
Photochem. Photobiol. |
pmid:18173725
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Hypericin uptake: a prognostic marker for survival in high-grade glioma. |
2008 |
J Clin Neurosci |
pmid:18394904
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Li S et al. |
Chemical markers for the quality control of herbal medicines: an overview. |
2008 |
Chin Med |
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In vitro perturbation of aggregation processes in beta-amyloid peptides: a spectroscopic study. |
2008 |
FEBS Lett. |
pmid:18805418
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Theodossiou TA et al. |
Molecular modeling and experimental evidence for hypericin as a substrate for mitochondrial complex III; mitochondrial photodamage as demonstrated using specific inhibitors. |
2008 |
Free Radic. Biol. Med. |
pmid:18852042
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Influence of the habitat altitude on the (proto)hypericin and (proto)pseudohypericin levels of hypericum plants from Crete. |
2008 |
Planta Med. |
pmid:18671196
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Hypericin as a marker for determination of tissue viability after intratumoral ethanol injection in a murine liver tumor model. |
2008 |
Acad Radiol |
pmid:18078913
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Boiy A et al. |
Photosensitizing activity of hypericin and hypericin acetate after topical application on normal mouse skin. |
2008 |
Br. J. Dermatol. |
pmid:18047507
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Zhao J et al. |
Photodynamic effect of hypericin on the conformation and catalytic activity of hemoglobin. |
2008 |
Int J Mol Sci |
pmid:19325739
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Aleisa AM |
Cytological and biochemical effects of St. John's Wort supplement (a complex mixture of St. John's Wort, Rosemary and Spirulina) on somatic and germ cells of Swiss Albino mice. |
2008 |
Int J Environ Res Public Health |
pmid:19151436
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Guo X et al. |
Increased p38-MAPK is responsible for chemotherapy resistance in human gastric cancer cells. |
2008 |
BMC Cancer |
pmid:19091131
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Radauer C et al. |
The Bet v 1 fold: an ancient, versatile scaffold for binding of large, hydrophobic ligands. |
2008 |
BMC Evol. Biol. |
pmid:18922149
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Morgan AJ and Jorm AF |
Self-help interventions for depressive disorders and depressive symptoms: a systematic review. |
2008 |
Ann Gen Psychiatry |
pmid:18710579
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Solár P et al. |
Erythropoietin inhibits apoptosis induced by photodynamic therapy in ovarian cancer cells. |
2008 |
Mol. Cancer Ther. |
pmid:18687658
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Clinically relevant safety issues associated with St. John's wort product labels. |
2008 |
BMC Complement Altern Med |
pmid:18637192
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Weber W et al. |
Hypericum perforatum (St John's wort) for attention-deficit/hyperactivity disorder in children and adolescents: a randomized controlled trial. |
2008 |
JAMA |
pmid:18544723
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