khellin

Khellin is a lipid of Polyketides (PK) class. The involved functions are known as Diastasis and Selection, Genetic.

Cross Reference

Introduction

To understand associated biological information of khellin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with khellin?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with khellin

MeSH term MeSH ID Detail
Mycobacterium Infections D009164 7 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with khellin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with khellin?

There are no associated biomedical information in the current reference collection.

What functions are associated with khellin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with khellin?

There are no associated biomedical information in the current reference collection.

What genes are associated with khellin?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with khellin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with khellin

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Authors Title Published Journal PubMed Link
Fenniche S et al. Association of khellin and 308-nm excimer lamp in the treatment of severe alopecia areata in a child. 2018 J Cosmet Laser Ther pmid:29020475
Nordlund JJ The Medical Treatment of Vitiligo: An Historical Review. 2017 Dermatol Clin pmid:28317520
Travaini ML et al. Khellin and Visnagin, Furanochromones from Ammi visnaga (L.) Lam., as Potential Bioherbicides. 2016 J. Agric. Food Chem. pmid:27936681
Pavela R et al. Larvicidal activity of extracts from Ammi visnaga Linn. (Apiaceae) seeds against Culex quinquefasciatus Say. (Diptera: Culicidae). 2016 Exp. Parasitol. pmid:26995534
Bagherani N The efficacy of 308 nm UV excimer light as monotherapy and combination therapy with topical khellin 4% and/or tacrolimus 0.1% in the treatment of vitiligo. 2016 Dermatol Ther pmid:26279072
Badr JM et al. Validated HPLC method for simultaneous estimation of khellol glucoside, khellin and visnagin in Ammi visnaga L. fruits and pharmaceutical preparations. 2015 Nat. Prod. Res. pmid:25111086
Liu Y et al. Visnagin protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase. 2014 Sci Transl Med pmid:25504881
Abdel Latif NA et al. Synthesis of new benzofuran-1,3-thiazolidin-4-one derivatives from natural sources and study of their antioxidant activity. 2013 Jul-Aug Bioorg. Khim. pmid:24707731
Hadad GM et al. Validated HPLC and HPTLC methods for simultaneous determination of colchicine and khellin in pharmaceutical formulations. 2013 J Chromatogr Sci pmid:22914568
Elgazwy AS et al. Molecular modeling study bioactive natural product of khellin analogues as a novel potential pharmacophore of EGFR inhibitors. 2013 J Enzyme Inhib Med Chem pmid:23025406
Vrzal R et al. Khellin and visnagin differentially modulate AHR signaling and downstream CYP1A activity in human liver cells. 2013 PLoS ONE pmid:24069365
El-Nakkady SS et al. Antitumor and antimicrobial activities of some hetero aromatic benzofurans derived from naturally occurring visnagin. 2012 Jul-Aug Acta Pol Pharm pmid:22876607
Janssen S et al. Exploring prospects of novel drugs for tuberculosis. 2012 Drug Des Devel Ther pmid:22973091
Normoyle KP and Brieher WM Cyclase-associated protein (CAP) acts directly on F-actin to accelerate cofilin-mediated actin severing across the range of physiological pH. 2012 J. Biol. Chem. pmid:22904322
Echauri-Espinosa RO et al. Coronin is a component of the endocytic collar of hyphae of Neurospora crassa and is necessary for normal growth and morphogenesis. 2012 PLoS ONE pmid:22693603
Dráber P et al. Cytoskeleton in mast cell signaling. 2012 Front Immunol pmid:22654883
Lei L et al. Cellulose synthase complexes: composition and regulation. 2012 Front Plant Sci pmid:22639663
Zuñiga J et al. Cellular and humoral mechanisms involved in the control of tuberculosis. 2012 Clin. Dev. Immunol. pmid:22666281
Williams HC et al. Role of coronin 1B in PDGF-induced migration of vascular smooth muscle cells. 2012 Circ. Res. pmid:22619279
Poirier CC et al. Deconvolution of the cellular force-generating subsystems that govern cytokinesis furrow ingression. 2012 PLoS Comput. Biol. pmid:22570593
Rana MK and Worthylake RA Novel mechanism for negatively regulating Rho-kinase (ROCK) signaling through Coronin1B protein in neuregulin 1 (NRG-1)-induced tumor cell motility. 2012 J. Biol. Chem. pmid:22563075
Montesanto A et al. Epidemiological, genetic and epigenetic aspects of the research on healthy ageing and longevity. 2012 Immun Ageing pmid:22524317
Meiler E et al. Cortactin tyrosine phosphorylation promotes its deacetylation and inhibits cell spreading. 2012 PLoS ONE pmid:22479425
Cooper RM et al. An excitable cortex and memory model successfully predicts new pseudopod dynamics. 2012 PLoS ONE pmid:22457772
Ignatev A et al. The lasso segment is required for functional dimerization of the Plasmodium formin 1 FH2 domain. 2012 PLoS ONE pmid:22428073
Wang S et al. Genetic dissection of the Canq1 locus governing variation in extent of the collateral circulation. 2012 PLoS ONE pmid:22412848
Haug KG et al. Nonlinear pharmacokinetics of visnagin in rats after intravenous bolus administration. 2012 Eur J Pharm Sci pmid:22085634
Chan KT et al. Coronin 1C harbours a second actin-binding site that confers co-operative binding to F-actin. 2012 Biochem. J. pmid:22364218
Zhang CY et al. Antioxidant properties of polysaccharide from the brown seaweed Sargassum graminifolium (Turn.), and its effects on calcium oxalate crystallization. 2012 Mar Drugs pmid:22363225
Xavier CP et al. Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migration. 2012 Sci Rep pmid:22355754
Wang Y et al. Transcription analysis on response of porcine alveolar macrophages to Haemophilus parasuis. 2012 BMC Genomics pmid:22330747
Kollmar M et al. Evolution of the eukaryotic ARP2/3 activators of the WASP family: WASP, WAVE, WASH, and WHAMM, and the proposed new family members WAWH and WAML. 2012 BMC Res Notes pmid:22316129
Patel NS et al. Advanced treatment modalities for vitiligo. 2012 Dermatol Surg pmid:22288899
Koo MS et al. Strain specific transcriptional response in Mycobacterium tuberculosis infected macrophages. 2012 Cell Commun. Signal pmid:22280836
Günther J et al. Lipopolysaccharide priming enhances expression of effectors of immune defence while decreasing expression of pro-inflammatory cytokines in mammary epithelia cells from cows. 2012 BMC Genomics pmid:22235868
Morley SC The actin-bundling protein L-plastin: a critical regulator of immune cell function. 2012 Int J Cell Biol pmid:22194750
Lapalikar GV et al. F420H2-dependent degradation of aflatoxin and other furanocoumarins is widespread throughout the actinomycetales. 2012 PLoS ONE pmid:22383957
Kilicaslan I and Coskun S Spontaneous stone passage: is it Ammi visnaga effect? 2012 Urol. Res. pmid:22990409
Haug KG et al. Pharmacokinetic evaluation of visnagin and Ammi visnaga aqueous extract after oral administration in rats. 2012 Planta Med. pmid:23096256
Hölttä-Vuori M et al. Endosomal actin remodeling by coronin-1A controls lipoprotein uptake and degradation in macrophages. 2012 Circ. Res. pmid:22223354
Seto S et al. Coronin-1a inhibits autophagosome formation around Mycobacterium tuberculosis-containing phagosomes and assists mycobacterial survival in macrophages. 2012 Cell. Microbiol. pmid:22256790
Conrad MD et al. Extensive genetic diversity, unique population structure and evidence of genetic exchange in the sexually transmitted parasite Trichomonas vaginalis. 2012 PLoS Negl Trop Dis pmid:22479659
Uyeda TQ et al. Stretching actin filaments within cells enhances their affinity for the myosin II motor domain. 2011 PLoS ONE pmid:22022566
Ichikawa D et al. GRAIL (gene related to anergy in lymphocytes) regulates cytoskeletal reorganization through ubiquitination and degradation of Arp2/3 subunit 5 and coronin 1A. 2011 J. Biol. Chem. pmid:22016387
Khan A et al. Antiurolithic activity of Origanum vulgare is mediated through multiple pathways. 2011 BMC Complement Altern Med pmid:22004514
Symons M Rac1 activation comes full circle. 2011 EMBO J. pmid:21975373
Yokoyama K et al. Rab27a negatively regulates phagocytosis by prolongation of the actin-coating stage around phagosomes. 2011 J. Biol. Chem. pmid:21169636
Watanabe M et al. Coronin7 forms a novel E3 ubiquitin ligase complex to promote the degradation of the anti-proliferative protein Tob. 2011 FEBS Lett. pmid:21130766
Eckert C et al. A holistic phylogeny of the coronin gene family reveals an ancient origin of the tandem-coronin, defines a new subfamily, and predicts protein function. 2011 BMC Evol. Biol. pmid:21943019
Shina MC et al. Redundant and unique roles of coronin proteins in Dictyostelium. 2011 Cell. Mol. Life Sci. pmid:20640912