D-cycloserine

D-cycloserine is a lipid of Polyketides (PK) class. D-cycloserine is associated with abnormalities such as Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis and Inflammatory Bowel Diseases. The involved functions are known as Cellular Infiltration, Vascular Permeability, Stimulus, antagonists and Kinase Inhibitors [MoA]. D-cycloserine often locates in Tissue membrane, Body tissue, Protoplasm, Endothelium and Cell Wall. The associated genes with D-cycloserine are Genome, serine O-sulfate, Polypeptides, alpha-aminobutyric acid, (S)-isomer and Genes, Reporter. The related lipids are Sphingolipids, Fatty Acids, Sterols, 25-hydroxycholesterol and Fatty Acids, Unsaturated.

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Introduction

To understand associated biological information of D-cycloserine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with D-cycloserine?

D-cycloserine is suspected in Tuberculosis, Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis, Inflammatory Bowel Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with D-cycloserine

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with D-cycloserine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with D-cycloserine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with D-cycloserine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with D-cycloserine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with D-cycloserine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with D-cycloserine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with D-cycloserine

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Authors Title Published Journal PubMed Link
Gazarini L et al. PTSD-like memory generated through enhanced noradrenergic activity is mitigated by a dual step pharmacological intervention targeting its reconsolidation. 2014 Int. J. Neuropsychopharmacol. pmid:25539509
Warmus BA et al. Tau-mediated NMDA receptor impairment underlies dysfunction of a selectively vulnerable network in a mouse model of frontotemporal dementia. 2014 J. Neurosci. pmid:25471585
Rathnaiah G et al. Generation and screening of a comprehensive Mycobacterium avium subsp. paratuberculosis transposon mutant bank. 2014 Front Cell Infect Microbiol pmid:25360421
Belloni V and Scaraffia PY Exposure to L-cycloserine incurs survival costs and behavioral alterations in Aedes aegypti females. 2014 Parasit Vectors pmid:25129074
Muscia GC et al. Design, synthesis and evaluation of acridine and fused-quinoline derivatives as potential anti-tuberculosis agents. 2014 Eur J Med Chem pmid:24412719
Mpagama SG et al. Plasma drug activity in patients on treatment for multidrug-resistant tuberculosis. 2014 Antimicrob. Agents Chemother. pmid:24247125
Ribbens JJ et al. Characterization and application of a disease-cell model for a neurodegenerative lysosomal disease. 2014 Mol. Genet. Metab. pmid:24094551
Rothbaum BO et al. A randomized, double-blind evaluation of D-cycloserine or alprazolam combined with virtual reality exposure therapy for posttraumatic stress disorder in Iraq and Afghanistan War veterans. 2014 Am J Psychiatry pmid:24743802
Handford CE et al. The effect of the mGlu5 negative allosteric modulator MTEP and NMDA receptor partial agonist D-cycloserine on Pavlovian conditioned fear. 2014 Int. J. Neuropsychopharmacol. pmid:24674862
Kugathasan R et al. Cycloserine as an alternative urinary tract infection therapy: susceptibilities of 500 urinary pathogens to standard and alternative therapy antimicrobials. 2014 Eur. J. Clin. Microbiol. Infect. Dis. pmid:24474246
Baran H and Kepplinger B D-Cycloserine lowers kynurenic acid formation--new mechanism of action. 2014 Eur Neuropsychopharmacol pmid:24189377
Shohami E and Biegon A Novel approach to the role of NMDA receptors in traumatic brain injury. 2014 CNS Neurol Disord Drug Targets pmid:24168367
Melkonian LO et al. [Regulation of key enzymes of L-alanine biosynthesis by Brevibacterium flavum producer strains]. 2013 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:23795472
Kuriyama K et al. Valproic acid but not D-cycloserine facilitates sleep-dependent offline learning of extinction and habituation of conditioned fear in humans. 2013 Neuropharmacology pmid:22992332
Chan HN et al. Augmenting transcranial direct current stimulation with (D)-cycloserine for depression: a pilot study. 2013 J ECT pmid:23792778
George L et al. Novel multidrug therapy for disseminated rhinosporidiosis, refractory to dapsone – case report. 2013 Trop Doct pmid:23796478
Gupta SC et al. Effect of D-cycloserine in conjunction with fear extinction training on extracellular signal-regulated kinase activation in the medial prefrontal cortex and amygdala in rat. 2013 Eur. J. Neurosci. pmid:23551217
Farrell LJ et al. Difficult-to-treat pediatric obsessive-compulsive disorder: feasibility and preliminary results of a randomized pilot trial of D-cycloserine-augmented behavior therapy. 2013 Depress Anxiety pmid:23722990
Hwang TJ et al. Safety of cycloserine and terizidone for the treatment of drug-resistant tuberculosis: a meta-analysis. 2013 Int. J. Tuberc. Lung Dis. pmid:23735593
Hofmann SG et al. D-Cycloserine as an augmentation strategy with cognitive-behavioral therapy for social anxiety disorder. 2013 Am J Psychiatry pmid:23599046