D-cycloserine

D-cycloserine is a lipid of Polyketides (PK) class. D-cycloserine is associated with abnormalities such as Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis and Inflammatory Bowel Diseases. The involved functions are known as Cellular Infiltration, Vascular Permeability, Stimulus, antagonists and Kinase Inhibitors [MoA]. D-cycloserine often locates in Tissue membrane, Body tissue, Protoplasm, Endothelium and Cell Wall. The associated genes with D-cycloserine are Genome, serine O-sulfate, Polypeptides, alpha-aminobutyric acid, (S)-isomer and Genes, Reporter. The related lipids are Sphingolipids, Fatty Acids, Sterols, 25-hydroxycholesterol and Fatty Acids, Unsaturated.

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Introduction

To understand associated biological information of D-cycloserine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with D-cycloserine?

D-cycloserine is suspected in Tuberculosis, Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis, Inflammatory Bowel Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with D-cycloserine

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with D-cycloserine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with D-cycloserine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with D-cycloserine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with D-cycloserine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with D-cycloserine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with D-cycloserine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with D-cycloserine

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Authors Title Published Journal PubMed Link
Dorozhkova IR and Volk AV [Frequency of Mycobacterium tuberculosis L-form induction under the influence of cycloserine and its combinations with other drugs]. 1972 Antibiotiki pmid:4120084
Dorozhkova IR and Volk AV [Dihydrostreptomycin as a factor inducing L-forms in Mycobacterium tuberculosis]. 1972 Antibiotiki pmid:4121154
SMOLNIKOVA NM [DISTRIBUTION OF D,L- AND D-CYCLOSERINE IN THE WHITE MOUSE]. 1963 Antibiotiki pmid:14076091
Shmelev NA and Shabalova LN [Effect of basic tuberculostatic preparations of the 1st and 2d order in the bioelectric activity of the brain in patients with pulmonary tuberculosis]. 1969 Antibiotiki pmid:5361831
KheÄ­fets LB and Kozlova NE [Quantitative evaluation of the effect of depression of Mycobacterium tuberculosis intracellular multiplication under the influence of antibacterial preparations]. 1975 Antibiotiki pmid:817645
Cheslak I et al. [Decomposition of cycloserine in the process of chemical treatment of culture fluid]. 1967 Antibiotiki pmid:5593966
Ivanova ES [Concentration of ethionamide and cycloserine in the blood of the patients with pulmonary tuberculosis]. 1967 Antibiotiki pmid:4968419
Shmelev NA et al. [Comparative clinical electroencephalographic study of cycloserine and terizidon tolerance]. 1975 Antibiotiki pmid:1091207
UTKIN VV [Cycloserine in experimental tuberculosis in monkeys]. 1962 Antibiotiki pmid:13995570
Krepak OM and Storozhev IA [Study of the functional state of the liver in animals under the effect of streptomycin, D-cycloserine, kanamycin and florimycin. Effect of antibiotics on blood plasma proteins]. 1970 Antibiotiki pmid:4099113
Makarevich NM and RudoÄ­ NM [Drug sensitivity of atypical Mycobacteria isolated from patients to antitubercular agents of the first and second order]. 1971 Antibiotiki pmid:4326726
Bialik IB [Kanamycin and florimycin in the clinical course of pulmonary tuberculosis]. 1971 Antibiotiki pmid:4326728
Popova LA and Stepanova NE [Study of physiology of the producer of cycloserine]. 1966 Antibiotiki pmid:5993084
Kuznetsov VD and Rodionova EG [Preservation of some Actinomycetes--producers of antibiotics by different methods]. 1970 Antibiotiki pmid:4321152
Krepak OM and Storozhev IA [Changes in the functional state of the liver in animals under the action of streptomycin, D-cycloserine, kanamycin and florimycin. Effect of antibiotics on alkaline phosphatase activity]. 1970 Antibiotiki pmid:4321154
Kulikova MF [Distribution of the range of natural sensitivity to antitubercular preparations in cultures of strains of mycobacterum BCG]. 1968 Antibiotiki pmid:4301383
Mkrtchian SV [Development of resistance of Mycobacterium tuberculosis to cycloserine, ethionamide, kanamycin, florimycin in experiments in vitro]. 1968 Antibiotiki pmid:4303355
Torbochkina LI [Molecular mechanism of inhibition of biosynthesis of peptidoglycan of bacterial cell walls by antibiotics]. 1970 Antibiotiki pmid:4915727
KIVMAN GIa and SMOLNIKOVA NM [CLEARANCE OF THE BLOOD SERUM FROM D- AND D,L-CYCLOSERINE IN THE RABBIT]. 1964 Antibiotiki pmid:14319176
KARTSEVA VD and BRUNS BP [A COLORIMETRIC METHOD FOR THE DETERMINATION OF CYCLOSERINE]. 1965 Antibiotiki pmid:14294439
Kagramanov AI et al. [Concentration of cycloserine in the blood of patients with pulmonary tuberculosis]. 1969 Antibiotiki pmid:4889841
BREGER MA [On biological activities of cycloserine and some of its analogues and homologues]. 1961 Antibiotiki pmid:13872752
Iakhontova LF et al. [Cycloserine sorption by sulfocation exchange resin from a solution containing hydrogen and sodium ions]. 1970 Antibiotiki pmid:5493477
Belogurova VP and Ivanitskaia NN [Viability of the drug resistant Mycobacterium tuberculosis (study by the proportion method)]. 1970 Antibiotiki pmid:5497632
Iakhontova LF et al. [Sorption of cycloserine by H-form of sulfurcation exchange resin]. 1970 Antibiotiki pmid:5497648
LEDNEVA RK et al. [Effect of cycloserine stereoisomers on the synthesis of proteins and lysis of cells in Bact. coli]. 1962 Antibiotiki pmid:14463446
Shmelev NA and Shabalova LN [Changes in the bioelectric activity of the brain in patients with pulmonary tuberculosis during intolerance cycloserine]. 1970 Antibiotiki pmid:5501372
MITROFANOV VS and RAZUMOVA IL [Morphological analysis of the effect of cycloserine on experimental tuberculosis in white mice]. 1960 Mar-Apr Antibiotiki pmid:14423030
RudoÄ­ NM et al. [Restoration of drug sensitivity in Mycobacterium tuberculosis to streptomycin and isoniazid during treatment with preparations of the 1st series]. 1970 Antibiotiki pmid:4993044
Cinatl J et al. Cytotoxicity of L-cycloserine against human neuroblastoma and medulloblastoma cells is associated with the suppression of ganglioside expression. 1999 Nov-Dec Anticancer Res. pmid:10697560
Neuhaus FC Selective inhibition of enzymes utilizing alanine in the biosynthesis of peptidoglycan. 1967 Antimicrob Agents Chemother (Bethesda) pmid:5596153
Nakatani Y et al. Role of Alanine Racemase Mutations in Mycobacterium tuberculosis d-Cycloserine Resistance. 2017 Antimicrob. Agents Chemother. pmid:28971867
Moreillon P et al. Two bactericidal targets for penicillin in pneumococci: autolysis-dependent and autolysis-independent killing mechanisms. 1990 Antimicrob. Agents Chemother. pmid:1691615
Clark VL and Young FE Inducible resistance to D-cycloserine in Bacillus subtilis 168. 1977 Antimicrob. Agents Chemother. pmid:406831
Clark VL and Young FE D-Cycloserine-induced alterations in the transport of D-alanine and glycine in Bacillus subtilis 168. 1977 Antimicrob. Agents Chemother. pmid:406832
Alangaden GJ et al. Mechanism of resistance to amikacin and kanamycin in Mycobacterium tuberculosis. 1998 Antimicrob. Agents Chemother. pmid:9593173
Xie Z et al. Differential antibiotic susceptibilities of starved Mycobacterium tuberculosis isolates. 2005 Antimicrob. Agents Chemother. pmid:16251329
Chacon O et al. Mycobacterium smegmatis D-Alanine Racemase Mutants Are Not Dependent on D-Alanine for Growth. 2002 Antimicrob. Agents Chemother. pmid:11751110
Hakenbeck R et al. Characterization of cell wall polymers secreted into the growth medium of lysis-defective pneumococci during treatment with penicillin and other inhibitors of cell wall synthesis. 1978 Antimicrob. Agents Chemother. pmid:25618
Ranaldi G et al. D-cycloserine uses an active transport mechanism in the human intestinal cell line Caco 2. 1994 Antimicrob. Agents Chemother. pmid:8092820
Charan M et al. Sulfur mobilization for Fe-S cluster assembly by the essential SUF pathway in the Plasmodium falciparum apicoplast and its inhibition. 2014 Antimicrob. Agents Chemother. pmid:24709262
Kurokawa K et al. Evaluation of target specificity of antibacterial agents using Staphylococcus aureus ddlA mutants and D-cycloserine in a silkworm infection model. 2009 Antimicrob. Agents Chemother. pmid:19546371
Fattorini L et al. Activities of moxifloxacin alone and in combination with other antimicrobial agents against multidrug-resistant Mycobacterium tuberculosis infection in BALB/c mice. 2003 Antimicrob. Agents Chemother. pmid:12499213
Uda N et al. Establishment of an in vitro D-cycloserine-synthesizing system by using O-ureido-L-serine synthase and D-cycloserine synthetase found in the biosynthetic pathway. 2013 Antimicrob. Agents Chemother. pmid:23529730
Kumagai T et al. Molecular cloning and heterologous expression of a biosynthetic gene cluster for the antitubercular agent D-cycloserine produced by Streptomyces lavendulae. 2010 Antimicrob. Agents Chemother. pmid:20086163
Peteroy M et al. Characterization of a Mycobacterium smegmatis mutant that is simultaneously resistant to D-cycloserine and vancomycin. 2000 Antimicrob. Agents Chemother. pmid:10817733
Gordon FB and Quan AL Susceptibility of Chlamydia to antibacterial drugs: test in cell cultures. 1972 Antimicrob. Agents Chemother. pmid:4790565
Utrup LJ et al. Susceptibilities of nontuberculosis mycobacterial species to amoxicillin-clavulanic acid alone and in combination with antimycobacterial agents. 1995 Antimicrob. Agents Chemother. pmid:7492084
Wise R and Andrews JM In vitro activity of fludalanine combined with pentizidone compared with those of other agents. 1984 Antimicrob. Agents Chemother. pmid:6610389
Sieradzki K et al. Role of a sodium-dependent symporter homologue in the thermosensitivity of beta-lactam antibiotic resistance and cell wall composition in Staphylococcus aureus. 2008 Antimicrob. Agents Chemother. pmid:18056270