D-cycloserine

D-cycloserine is a lipid of Polyketides (PK) class. D-cycloserine is associated with abnormalities such as Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis and Inflammatory Bowel Diseases. The involved functions are known as Cellular Infiltration, Vascular Permeability, Stimulus, antagonists and Kinase Inhibitors [MoA]. D-cycloserine often locates in Tissue membrane, Body tissue, Protoplasm, Endothelium and Cell Wall. The associated genes with D-cycloserine are Genome, serine O-sulfate, Polypeptides, alpha-aminobutyric acid, (S)-isomer and Genes, Reporter. The related lipids are Sphingolipids, Fatty Acids, Sterols, 25-hydroxycholesterol and Fatty Acids, Unsaturated.

Cross Reference

Introduction

To understand associated biological information of D-cycloserine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with D-cycloserine?

D-cycloserine is suspected in Tuberculosis, Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis, Inflammatory Bowel Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with D-cycloserine

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with D-cycloserine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with D-cycloserine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with D-cycloserine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with D-cycloserine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with D-cycloserine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with D-cycloserine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with D-cycloserine

Download all related citations
Per page 10 20 50 100 | Total 2271
Authors Title Published Journal PubMed Link
pmid:
Snell K Alanine release by rat hemidiaphragm muscle in vitro. 1976 Biochem. Soc. Trans. pmid:1001666
Riekkinen P et al. Tetrahydroaminoacridine and D-cycloserine fail to alleviate the water maze spatial navigation defect induced by hippocampal inactivation. 1999 Eur. J. Pharmacol. pmid:10064146
Goff DC et al. A placebo-controlled crossover trial of D-cycloserine added to clozapine in patients with schizophrenia. 1999 Biol. Psychiatry pmid:10071726
Tsai GE et al. Improved cognition in Alzheimer's disease with short-term D-cycloserine treatment. 1999 Am J Psychiatry pmid:10080566
Goff DC What is the role of glutamate in schizophrenia? 1999 Harv Ment Health Lett pmid:10092340
Forschbach G [Drug therapy of pulmonary tuberculosis]. 1978 Prax Klin Pneumol pmid:103085
Cordi A et al. Design, synthesis and structure-activity relationships of novel strychnine-insensitive glycine receptor ligands. 1999 Bioorg. Med. Chem. Lett. pmid:10360746
van Berckel BN et al. D-cycloserine increases positive symptoms in chronic schizophrenic patients when administered in addition to antipsychotics: a double-blind, parallel, placebo-controlled study. 1999 Neuropsychopharmacology pmid:10432468
Rosenquist TH et al. N-methyl-D-aspartate receptor agonists modulate homocysteine-induced developmental abnormalities. 1999 FASEB J. pmid:10463943
Panaro NJ et al. Flavone acetic acid induces a G2/M cell cycle arrest in mammary carcinoma cells. 1999 Br. J. Cancer pmid:10471038
Pussinen R and Sirviö J Effects of D-cycloserine, a positive modulator of N-methyl-D-aspartate receptors, and ST 587, a putative alpha-1 adrenergic agonist, individually and in combination, on the non-delayed and delayed foraging behaviour of rats assessed in the radial arm maze. 1999 J. Psychopharmacol. (Oxford) pmid:10475724
O'Connor KA and Zusman DR Induction of beta-lactamase influences the course of development in Myxococcus xanthus. 1999 J. Bacteriol. pmid:10515921
Malone RS et al. The effect of hemodialysis on cycloserine, ethionamide, para-aminosalicylate, and clofazimine. 1999 Chest pmid:10531163
Land C and Riccio DC d-Cycloserine: effects on long-term retention of a conditioned response and on memory for contextual attributes. 1999 Neurobiol Learn Mem pmid:10536095
Akopyan TN et al. Beta-cyanoalanine synthase: purification and characterization. 1975 Proc. Natl. Acad. Sci. U.S.A. pmid:1055433
Malashkevich VN et al. Crystal structures of dialkylglycine decarboxylase inhibitor complexes. 1999 J. Mol. Biol. pmid:10556038
Durek C et al. Interference of modern antibacterials with bacillus Calmette-Guerin viability. 1999 J. Urol. pmid:10569547
Durek C et al. Sensitivity of BCG to modern antibiotics. 2000 Eur. Urol. pmid:10575268
Barry CE et al. Use of genomics and combinatorial chemistry in the development of new antimycobacterial drugs. 2000 Biochem. Pharmacol. pmid:10609550
Denisova NA et al. The role of glutathione, membrane sphingomyelin, and its metabolites in oxidative stress-induced calcium "dysregulation" in PC12 cells. 1999 Free Radic. Biol. Med. pmid:10641723
Ramaswamy S and Musser JM Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 update. 1998 Tuber. Lung Dis. pmid:10645439
Fattorini L et al. Activity of 16 antimicrobial agents against drug-resistant strains of Mycobacterium tuberculosis. 1999 Microb. Drug Resist. pmid:10647084
Karcz-Kubicha M et al. NMDA receptor antagonists acting at the glycineB site in rat models for antipsychotic-like activity. 1999 J Neural Transm pmid:10651113
Cinatl J et al. Cytotoxicity of L-cycloserine against human neuroblastoma and medulloblastoma cells is associated with the suppression of ganglioside expression. 1999 Nov-Dec Anticancer Res. pmid:10697560
Fujita H et al. A possible involvement of ion transporter in tumor necrosis factor alpha and cycloheximide-induced apoptosis of endothelial cells. 1999 Mediators Inflamm. pmid:10704075
D'Souza DC et al. IV glycine and oral D-cycloserine effects on plasma and CSF amino acids in healthy humans. 2000 Biol. Psychiatry pmid:10704956
Aura J and Riekkinen P Pre-training blocks the improving effect of tetrahydroaminoacridine and D-cycloserine on spatial navigation performance in aged rats. 2000 Eur. J. Pharmacol. pmid:10708739
Schneider JS et al. Effects of the partial glycine agonist D-cycloserine on cognitive functioning in chronic low dose MPTP-treated monkeys. 2000 Brain Res. pmid:10727642
Kovács P The effect of beta-chloro D-alanine and L-cycloserine on the serine, phosphorus and palmitic acid uptake and metabolism of Tetrahymena lipids. 1999 Acta. Biol. Hung. pmid:10735173
LeVine SM et al. L-cycloserine slows the clinical and pathological course in mice with globoid cell leukodystrophy (twitcher mice). 2000 J. Neurosci. Res. pmid:10740228
Depoortere R et al. Prepulse inhibition of the startle reflex in rats: effects of compounds acting at various sites on the NMDA receptor complex. 1999 Behav Pharmacol pmid:10780302
Peteroy M et al. Characterization of a Mycobacterium smegmatis mutant that is simultaneously resistant to D-cycloserine and vancomycin. 2000 Antimicrob. Agents Chemother. pmid:10817733
Leveque JC et al. Intracellular modulation of NMDA receptor function by antipsychotic drugs. 2000 J. Neurosci. pmid:10818136
Harper DN An assessment and comparison of the effects of oxotremorine, D-cycloserine, and bicuculline on delayed matching-to-sample performance in rats. 2000 Exp Clin Psychopharmacol pmid:10843304
Rosner A et al. Evaluation of several enrichment procedures for the isolation of recombinant plasmid DNA. 1979 Mol. Biol. Rep. pmid:108533
De Sarro G et al. Influence of D-cycloserine on the anticonvulsant activity of some antiepileptic drugs against audiogenic seizures in DBA/2 mice. 2000 Epilepsy Res. pmid:10863138
Cole AM et al. Characterization of a fish antimicrobial peptide: gene expression, subcellular localization, and spectrum of activity. 2000 Antimicrob. Agents Chemother. pmid:10898673
Shmelev NA et al. [Comparative clinical electroencephalographic study of cycloserine and terizidon tolerance]. 1975 Antibiotiki pmid:1091207
Víznerová A [Criteria of resistance of some antibiotics and chemotherapeutics for strains of Mycobacterium tuberculosis isolated in Czechoslovakia. Cycloserin, ethionamide, pyrazinamide, rifampicin, and ethambutol (author's transl)]. 1979 Cas. Lek. Cesk. pmid:109213
Raunio RP and Leppävirta M The effect of culture age, chloramphenicol and B6 inhibitors on intra- and extracellular keto and amino acids of Escherichia coli B. 1975 J. Gen. Microbiol. pmid:1094092
Investigations of allergic status and blood counts in Chinese patients receiving daily or intermittent rifampicin in Hong Kong. 1975 Clin. Allergy pmid:1095248
Dong Y et al. Mutant prevention concentration as a measure of antibiotic potency: studies with clinical isolates of Mycobacterium tuberculosis. 2000 Antimicrob. Agents Chemother. pmid:10952625
Nakazato E et al. Cholinergic and glutamatergic activation reverses working memory failure by hippocampal histamine H1 receptor blockade in rats. 2000 Life Sci. pmid:10954048
Sammes PG Naturally occurring 2,5-dioxopiperazines and related compounds. 1975 Fortschr Chem Org Naturst pmid:1100502
Klapwijk PM et al. An enrichment technique for auxotrophs of Agrobacterium tumefaciens using a combination of carbenicillin and lysozyme. 1975 J. Gen. Microbiol. pmid:1104767
Klodzińska A and Chojnacka-Wójcik E Anticonflict effect of the glycineB receptor partial agonist, D-cycloserine, in rats. Pharmacological analysis. 2000 Psychopharmacology (Berl.) pmid:11057527
Kim YG et al. Bioequivalence assessment of closerin capsule to dura seromycin capsule of cycloserine after a single oral dose administration to healthy male volunteers. 2000 Int J Clin Pharmacol Ther pmid:11073286
Carhart G and Hegeman G Improved method of selection for mutants of Pseudomonas putida. 1975 Appl Microbiol pmid:1108792
Kahana LM et al. Clinical aspects of atypical mycobacterial infection. 1975 Can Med Assoc J pmid:1109749
Greene R et al. Short-term and long-term effects of N-methyl-D-aspartate receptor hypofunction. 2000 Arch. Gen. Psychiatry pmid:11115333
Carpenter WT New style clinical trials in schizophrenia. 1999 Curr Psychiatry Rep pmid:11122899
Javitt DC Treatment of negative and cognitive symptoms. 1999 Curr Psychiatry Rep pmid:11122902
David S Synergic activity of D-cycloserine and beta-chloro-D-alanine against Mycobacterium tuberculosis. 2001 J. Antimicrob. Chemother. pmid:11157908
Noda A et al. Phencyclidine impairs latent learning in mice: interaction between glutamatergic systems and sigma(1) receptors. 2001 Neuropsychopharmacology pmid:11182540
Dall'Olio R et al. D-Cycloserine, a positive modulator of NMDA receptors, inhibits serotonergic function. 2000 Behav Pharmacol pmid:11198134
Berning SE The role of fluoroquinolones in tuberculosis today. 2001 Drugs pmid:11217874
Su WJ et al. Utility of PCR assays for rapid diagnosis of BCG infection in children. 2001 Int. J. Tuberc. Lung Dis. pmid:11334259
Rando RR On the mechanism of action of antibiotics which act as irreversible enzyme inhibitors. 1975 Biochem. Pharmacol. pmid:1137602
Walsh SE et al. Possible mechanisms for the relative efficacies of ortho-phthalaldehyde and glutaraldehyde against glutaraldehyde-resistant Mycobacterium chelonae. 2001 J. Appl. Microbiol. pmid:11442717
Malina HZ et al. Pathological apoptosis by xanthurenic acid, a tryptophan metabolite: activation of cell caspases but not cytoskeleton breakdown. 2001 BMC Physiol. pmid:11459518
Sheinin A et al. Subunit specificity and mechanism of action of NMDA partial agonist D-cycloserine. 2001 Neuropharmacology pmid:11489451
Wechsler M and Lattimer JK An evaluation of the current therapeutic regimen for renal tuberculosis. 1975 J. Urol. pmid:1152148
Lelong V et al. RS 67333 and D-cycloserine accelerate learning acquisition in the rat. 2001 Neuropharmacology pmid:11543772
Aukee S et al. Drug absorption in patients with T-tube after cholecystectomy. 1975 Ann. Clin. Res. pmid:1155910
David V et al. Determination of cycloserine in human plasma by high-performance liquid chromatography with fluorescence detection, using derivatization with p-benzoquinone. 2001 J. Chromatogr. B Biomed. Sci. Appl. pmid:11585129
Azare J et al. Selective susceptibility of transformed T lymphocytes to induction of apoptosis by PSC 833, an inhibitor of P-glycoprotein. 2001 Oncol. Res. pmid:11589302
Cruz MC et al. Rapamycin and less immunosuppressive analogs are toxic to Candida albicans and Cryptococcus neoformans via FKBP12-dependent inhibition of TOR. 2001 Antimicrob. Agents Chemother. pmid:11600372
Kozulitsyna TI and Kozlova NV [Ultrastructural change in Mycobacterium tuberculosis under the influence of antibacterial preparations (a review of the literature)]. 1979 Probl Tuberk pmid:116217
Hanauer SB Can cyclosporine go it alone in severe ulcerative colitis? 2001 Curr Gastroenterol Rep pmid:11696281
Gaiardi M et al. Effects of N-methyl-D-aspartate agonists and antagonists in rats discriminating amphetamine. 2001 Behav Pharmacol pmid:11710746
Matsumoto Y et al. Involvement of cholinergic and glutamatergic functions in working memory impairment induced by interleukin-1beta in rats. 2001 Eur. J. Pharmacol. pmid:11711044
Zhu M et al. Pharmacokinetics of cycloserine under fasting conditions and with high-fat meal, orange juice, and antacids. 2001 Pharmacotherapy pmid:11718495
Peloquin CA et al. Pharmacokinetics of para-aminosalicylic acid granules under four dosing conditions. 2001 Ann Pharmacother pmid:11724078
LaNoue KF et al. Role of specific aminotransferases in de novo glutamate synthesis and redox shuttling in the retina. 2001 J. Neurosci. Res. pmid:11746419
Chacon O et al. Mycobacterium smegmatis D-Alanine Racemase Mutants Are Not Dependent on D-Alanine for Growth. 2002 Antimicrob. Agents Chemother. pmid:11751110
Biswas S and LeVine SM Substrate-reduction therapy enhances the benefits of bone marrow transplantation in young mice with globoid cell leukodystrophy. 2002 Pediatr. Res. pmid:11756638
Meijer AJ et al. Rate-limiting factors in the oxidation of ethanol by isolated rat liver cells. 1975 Biochem. J. pmid:1180914
Andersen JM et al. Effects of scopolamine and D-cycloserine on non-spatial reference memory in rats. 2002 Behav. Brain Res. pmid:11809513
Meijer AJ et al. Role of anion translocation across the mitochondrial membrane in the regulation of urea synthesis from ammonia by isolated rat hepatocytes. 1975 J. Biol. Chem. pmid:1182028
Strømme Johannesen T and Myhrer T Impaired visual memory in rats reared in isolation is reversed by D-cycloserine in the adult rat. 2002 Eur. J. Pharmacol. pmid:11864642
Heresco-Levy U et al. Placebo-controlled trial of D-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophrenia. 2002 Am J Psychiatry pmid:11870017
Ethionamide+cycloserine+pas vs isoniazid+streptomycin+pas in initial antiburerculosis chemotherapy followed by the standard regimen. A controlled study with special reference to the microscopic enumeration of bacillia as a criterion of efficacy. 1975 Pneumonologie pmid:1187376
Walker DL et al. Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of D-cycloserine as assessed with fear-potentiated startle in rats. 2002 J. Neurosci. pmid:11896173
Gómez del Pulgar T et al. De novo-synthesized ceramide is involved in cannabinoid-induced apoptosis. 2002 Biochem. J. pmid:11903061
Rastogi N and Venkitasubramanian TA Preparation of protoplasts and whole cell ghosts from Mycobacterium smegmatis. 1979 J. Gen. Microbiol. pmid:119034
Thorsteinsson T et al. Cycloserine fatty acid derivatives as prodrugs: synthesis, degradation and in vitro skin permeability. 2002 Chem. Pharm. Bull. pmid:11964011
Erhardt S and Engberg G Increased phasic activity of dopaminergic neurones in the rat ventral tegmental area following pharmacologically elevated levels of endogenous kynurenic acid. 2002 Acta Physiol. Scand. pmid:11982504
Sun D et al. A pathway-specific cell based screening system to detect bacterial cell wall inhibitors. 2002 J. Antibiot. pmid:12014443
Cook SP et al. Direct calcium binding results in activation of brain serine racemase. 2002 J. Biol. Chem. pmid:12021263
Azzouz N et al. Evidence for de novo sphingolipid biosynthesis in Toxoplasma gondii. 2002 Int. J. Parasitol. pmid:12062486
Gupta SR et al. Synthesis of aflatoxins by the non-growing mycelia of Aspergillus parasiticus and the effect of inhibitors. 1975 J. Gen. Microbiol. pmid:1206377
Laake K and Oeksengaard AR D-cycloserine for Alzheimer's disease. 2002 Cochrane Database Syst Rev pmid:12076471
Koch M [Pharmacological support of exposure therapy in anxiety disorders. Animal experiment studies]. 2002 Nervenarzt pmid:12078031
Evins AE et al. D-Cycloserine added to risperidone in patients with primary negative symptoms of schizophrenia. 2002 Schizophr. Res. pmid:12084415
Takács J and Imreh EZ Use of D-cycloserine bitartarate for selective isolation of Clostridia. 1975 Acta Vet Acad Sci Hung pmid:1233872
Wechsler H Ethambutol regimen in renal tuberculosis. 1975 J. Urol. pmid:1235368
Peloquin CA Therapeutic drug monitoring in the treatment of tuberculosis. 2002 Drugs pmid:12381217
Erdreich-Epstein A et al. Ceramide signaling in fenretinide-induced endothelial cell apoptosis. 2002 J. Biol. Chem. pmid:12388538
Bron PA et al. Use of the alr gene as a food-grade selection marker in lactic acid bacteria. 2002 Appl. Environ. Microbiol. pmid:12406763