D-cycloserine

D-cycloserine is a lipid of Polyketides (PK) class. D-cycloserine is associated with abnormalities such as Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis and Inflammatory Bowel Diseases. The involved functions are known as Cellular Infiltration, Vascular Permeability, Stimulus, antagonists and Kinase Inhibitors [MoA]. D-cycloserine often locates in Tissue membrane, Body tissue, Protoplasm, Endothelium and Cell Wall. The associated genes with D-cycloserine are Genome, serine O-sulfate, Polypeptides, alpha-aminobutyric acid, (S)-isomer and Genes, Reporter. The related lipids are Sphingolipids, Fatty Acids, Sterols, 25-hydroxycholesterol and Fatty Acids, Unsaturated.

Cross Reference

Introduction

To understand associated biological information of D-cycloserine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with D-cycloserine?

D-cycloserine is suspected in Tuberculosis, Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis, Inflammatory Bowel Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with D-cycloserine

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with D-cycloserine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with D-cycloserine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with D-cycloserine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with D-cycloserine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with D-cycloserine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with D-cycloserine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with D-cycloserine

Download all related citations
Per page 10 20 50 100 | Total 2271
Authors Title Published Journal PubMed Link
Grassi G and Pallanti S Current and up-and-coming pharmacotherapy for obsessive-compulsive disorder in adults. 2018 Expert Opin Pharmacother pmid:30321070
Shin Y et al. D-cycloserine nasal formulation development for anxiety disorders by using polymeric gels. 2018 Drug Discov Ther pmid:29998995
Ranjan R et al. Preparation and optimization of a dry powder for inhalation of second-line anti-tuberculosis drugs. 2018 Int J Pharm pmid:29852204
George SA et al. D-Cycloserine Facilitates Reversal in an Animal Model of Post-traumatic Stress Disorder. 2018 Behav. Brain Res. pmid:29580893
Zhang W et al. Determination of cycloserine in microdialysis samples using liquid chromatography-tandem mass spectrometry with benzoyl chloride derivatization. 2018 Biomed. Chromatogr. pmid:29314157
Sugiyama A et al. Administration of riluzole to the basolateral amygdala facilitates fear extinction in rats. 2018 Behav. Brain Res. pmid:28843863
Huang CC et al. In vitro activity of aminoglycosides, clofazimine, d-cycloserine and dapsone against 83 Mycobacterium avium complex clinical isolates. 2018 J Microbiol Immunol Infect pmid:28705770
Jangra MS and Chhabra M Cycloserine Induced Suicidal Tendencies and Kanamycin Induced Ototoxicity in Indian MDR-TB Patient: A Case Report. 2018 Curr Drug Saf pmid:29866015
Muller C et al. The role of the CroR response regulator in resistance of Enterococcus faecalis to D-cycloserine is defined using an inducible receiver domain. 2018 Mol. Microbiol. pmid:29205552
Batson S et al. Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine. 2017 Nat Commun pmid:29208891
Nakatani Y et al. Role of Alanine Racemase Mutations in Mycobacterium tuberculosis d-Cycloserine Resistance. 2017 Antimicrob. Agents Chemother. pmid:28971867
Chen J et al. Identification of novel mutations associated with cycloserine resistance in Mycobacterium tuberculosis. 2017 J. Antimicrob. Chemother. pmid:28961957
Park S et al. Treatment outcomes of rifampin-sparing treatment in patients with pulmonary tuberculosis with rifampin-mono-resistance or rifampin adverse events: A retrospective cohort analysis. 2017 Respir Med pmid:28947041
Hofmeijer-Sevink MK et al. No Effects of D-Cycloserine Enhancement in Exposure With Response Prevention Therapy in Panic Disorder With Agoraphobia: A Double-Blind, Randomized Controlled Trial. 2017 J Clin Psychopharmacol pmid:28820746
Klass A et al. d-Cycloserine facilitates extinction learning and enhances extinction-related brain activation. 2017 Neurobiol Learn Mem pmid:28807795
Malan-Müller S et al. The role of microRNAs in the therapeutic action of D-cycloserine in a post-traumatic stress disorder animal model: an exploratory study. 2017 Psychiatr. Genet. pmid:28574862
Forsyth JK et al. Effects of Augmenting N-Methyl-D-Aspartate Receptor Signaling on Working Memory and Experience-Dependent Plasticity in Schizophrenia: An Exploratory Study Using Acute d-cycloserine. 2017 Schizophr Bull pmid:28338977
Baker KD and Richardson R Pharmacological evidence that a failure to recruit NMDA receptors contributes to impaired fear extinction retention in adolescent rats. 2017 Neurobiol Learn Mem pmid:27815216
Na ES et al. D-cycloserine improves synaptic transmission in an animal mode of Rett syndrome. 2017 PLoS ONE pmid:28813484
Bürkner PC et al. D-cycloserine augmentation of behavior therapy for anxiety and obsessive-compulsive disorders: A meta-analysis. 2017 PLoS ONE pmid:28282427
Wink LK et al. d-Cycloserine enhances durability of social skills training in autism spectrum disorder. 2017 Mol Autism pmid:28138381
Rismondo J et al. Suppressor Mutations Linking gpsB with the First Committed Step of Peptidoglycan Biosynthesis in Listeria monocytogenes. 2017 J. Bacteriol. pmid:27795316
Goff DC D-cycloserine in Schizophrenia: New Strategies for Improving Clinical Outcomes by Enhancing Plasticity. 2017 Curr Neuropharmacol pmid:26915421
Tremiño L et al. Studies on cyanobacterial protein PipY shed light on structure, potential functions, and vitamin B -dependent epilepsy. 2017 FEBS Lett. pmid:28914444
Tabuchi F et al. D-cycloserine increases the effectiveness of vancomycin against vancomycin-highly resistant Staphylococcus aureus. 2017 J. Antibiot. pmid:28588223
Sugiyama A et al. Administration of riluzole into the basolateral amygdala has an anxiolytic-like effect and enhances recognition memory in the rat. 2017 Behav. Brain Res. pmid:28359884
Saitoh A et al. Post-reexposure administration of D-cycloserine facilitates reconsolidation of contextual conditioned fear memory in rats. 2017 J Neural Transm (Vienna) pmid:28275863
Amorim Franco TM et al. Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d- and l-Cycloserine. 2017 ACS Chem. Biol. pmid:28272868
Huang Y et al. Modulating the Balance of Synaptic and Extrasynaptic NMDA Receptors Shows Positive Effects against Amyloid-β-Induced Neurotoxicity. 2017 J. Alzheimers Dis. pmid:28269783
Li C et al. [A preliminary study on the molecular characteristics of D-cycloserine resistance of ]. 2017 Zhonghua Liu Xing Bing Xue Za Zhi pmid:28231674
Mataix-Cols D et al. D-Cycloserine Augmentation of Exposure-Based Cognitive Behavior Therapy for Anxiety, Obsessive-Compulsive, and Posttraumatic Stress Disorders: A Systematic Review and Meta-analysis of Individual Participant Data. 2017 JAMA Psychiatry pmid:28122091
Tassoni R et al. Structural and functional characterization of the alanine racemase from Streptomyces coelicolor A3(2). 2017 Biochem. Biophys. Res. Commun. pmid:28042035
Takiguchi K et al. Association of schizophrenia onset age and white matter integrity with treatment effect of D-cycloserine: a randomized placebo-controlled double-blind crossover study. 2017 BMC Psychiatry pmid:28701225
Sta Maria NS et al. D-Cycloserine Restores Experience-Dependent Neuroplasticity after Traumatic Brain Injury in the Developing Rat Brain. 2017 J. Neurotrauma pmid:27931146
Shimizu S et al. Glycine-Binding Site Stimulants of NMDA Receptors Alleviate Extrapyramidal Motor Disorders by Activating the Nigrostriatal Dopaminergic Pathway. 2017 Int J Mol Sci pmid:28671605
de Leeuw AS et al. d-cycloserine addition to exposure sessions in the treatment of patients with obsessive-compulsive disorder. 2017 Eur. Psychiatry pmid:27837671
Sharp WG et al. Successful pharmacotherapy for the treatment of severe feeding aversion with mechanistic insights from cross-species neuronal remodeling. 2017 Transl Psychiatry pmid:28632204
Yates JR et al. Effects of N-methyl-D-aspartate receptor ligands on sensitivity to reinforcer magnitude and delayed reinforcement in a delay-discounting procedure. 2017 Psychopharmacology (Berl.) pmid:27837332
Ebrahimi C et al. Combining D-cycloserine with appetitive extinction learning modulates amygdala activity during recall. 2017 Neurobiol Learn Mem pmid:28512009
Goodman J et al. Enhancing and impairing extinction of habit memory through modulation of NMDA receptors in the dorsolateral striatum. 2017 Neuroscience pmid:28377177
Mao Z et al. A simplified LC-MS/MS method for rapid determination of cycloserine in small-volume human plasma using protein precipitation coupled with dilution techniques to overcome matrix effects and its application to a pharmacokinetic study. 2017 Anal Bioanal Chem pmid:28224247
Sogebi OA et al. Clinical predictors of aminoglycoside-induced ototoxicity in drug-resistant Tuberculosis patients on intensive therapy. 2017 Auris Nasus Larynx pmid:27832910
Olden M et al. Pilot Study of a Telehealth-Delivered Medication-Augmented Exposure Therapy Protocol for PTSD. 2017 J. Nerv. Ment. Dis. pmid:27441461
McGuire JF et al. A Meta-Analysis of D-Cycloserine in Exposure-Based Treatment: Moderators of Treatment Efficacy, Response, and Diagnostic Remission. 2017 J Clin Psychiatry pmid:27314661
Kim SW et al. Low-Dose d-Cycloserine for Depression? 2016 J Clin Psychiatry pmid:27561144
Hofmann SG Schrödinger's Cat and d-Cycloserine to Augment Exposure Therapy-Both Are Alive and Dead. 2016 JAMA Psychiatry pmid:27367470
Choi JH et al. [Concomitant Drug Reaction with Eosinophilia and Systemic Symptom Syndrome from Ethambutol and Autoimmune Hepatitis from Isoniazid]. 2016 Korean J Gastroenterol pmid:27206439
Norrholm SD et al. Baseline psychophysiological and cortisol reactivity as a predictor of PTSD treatment outcome in virtual reality exposure therapy. 2016 Behav Res Ther pmid:27183343
Meuret AE et al. The desire to belong: Social identification as a predictor of treatment outcome in social anxiety disorder. 2016 Behav Res Ther pmid:27070526
Desjardins CA et al. Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance. 2016 Nat. Genet. pmid:27064254
Minshawi NF et al. A randomized, placebo-controlled trial of D-cycloserine for the enhancement of social skills training in autism spectrum disorders. 2016 Mol Autism pmid:26770664
Otto MW et al. Enhancement of Psychosocial Treatment With D-Cycloserine: Models, Moderators, and Future Directions. 2016 Biol. Psychiatry pmid:26520240
Schade S and Paulus W D-Cycloserine in Neuropsychiatric Diseases: A Systematic Review. 2016 Int. J. Neuropsychopharmacol. pmid:26364274
Housman ST et al. Isolation and quantitation of Clostridium difficile in aqueous and fecal matter using two types of selective media. 2016 J Microbiol Immunol Infect pmid:26198865
Kantrowitz JT et al. d-Cycloserine, an NMDA Glutamate Receptor Glycine Site Partial Agonist, Induces Acute Increases in Brain Glutamate Plus Glutamine and GABA Comparable to Ketamine. 2016 Am J Psychiatry pmid:27903101
Rapee RM et al. d-Cycloserine does not enhance the effects of in vivo exposure among young people with broad-based anxiety disorders. 2016 Behav Res Ther pmid:27771572
Hu P et al. Hematopoietic Stem cell transplantation and lentiviral vector-based gene therapy for Krabbe's disease: Present convictions and future prospects. 2016 J. Neurosci. Res. pmid:27638600
Mikulka CR and Sands MS Treatment for Krabbe's disease: Finding the combination. 2016 J. Neurosci. Res. pmid:27638598
Schnitzer TJ et al. A randomized placebo-controlled pilot study of the efficacy and safety of D-cycloserine in people with chronic back pain. 2016 Mol Pain pmid:27852965
Ortiz V et al. Effect of a positive reinforcing stimulus on fear memory reconsolidation in ethanol withdrawn rats: Influence of d-cycloserine. 2016 Behav. Brain Res. pmid:27522017
Prasad R et al. Frequency of adverse events observed with second-line drugs among patients treated for multidrug-resistant tuberculosis. 2016 Indian J Tuberc pmid:27451820
Kapolowicz MR and Thompson LT Acute high-intensity noise induces rapid Arc protein expression but fails to rapidly change GAD expression in amygdala and hippocampus of rats: Effects of treatment with D-cycloserine. 2016 Hear. Res. pmid:27702572
Eniyan K et al. Development of a one-pot assay for screening and identification of Mur pathway inhibitors in Mycobacterium tuberculosis. 2016 Sci Rep pmid:27734910
Günthner J et al. The NMDA receptor partial agonist d-cycloserine does not enhance motor learning. 2016 J. Psychopharmacol. (Oxford) pmid:27436230
Sartori SB et al. Combined Neuropeptide S and D-Cycloserine Augmentation Prevents the Return of Fear in Extinction-Impaired Rodents: Advantage of Dual versus Single Drug Approaches. 2016 Int. J. Neuropsychopharmacol. pmid:26625894
Liraz-Zaltsman S et al. Neuroinflammation-Induced Memory Deficits Are Amenable to Treatment with D-Cycloserine. 2016 J. Mol. Neurosci. pmid:27421842
Storch EA et al. Efficacy of Augmentation of Cognitive Behavior Therapy With Weight-Adjusted d-Cycloserine vs Placebo in Pediatric Obsessive-Compulsive Disorder: A Randomized Clinical Trial. 2016 JAMA Psychiatry pmid:27367832
Otto MW et al. RANDOMIZED TRIAL OF D-CYCLOSERINE ENHANCEMENT OF COGNITIVE-BEHAVIORAL THERAPY FOR PANIC DISORDER. 2016 Depress Anxiety pmid:27315514
Goff D The Therapeutic Role of d-Cycloserine in Schizophrenia. 2016 Adv. Pharmacol. pmid:27288073
Otto MW et al. Examining the efficacy of d-cycloserine to augment therapeutic learning in depression. 2016 Contemp Clin Trials pmid:27094721
Yu X et al. Sensititre® MYCOTB MIC plate for drug susceptibility testing of Mycobacterium tuberculosis complex isolates. 2016 Int. J. Tuberc. Lung Dis. pmid:27046713
Smits JA et al. Enhancing panic and smoking reduction treatment with d-cycloserine: Study protocol for a randomized controlled trial. 2016 Contemp Clin Trials pmid:27015966
Fang A and Wilhelm S Antidepressant use with d-Cycloserine may block fear extinction. 2016 Evid Based Ment Health pmid:26792833
Qiu W et al. d-Alanine metabolism is essential for growth and biofilm formation of Streptococcus mutans. 2016 Mol Oral Microbiol pmid:26526529
Malan-Müller S et al. Molecular mechanisms of D-cycloserine in facilitating fear extinction: insights from RNAseq. 2016 Metab Brain Dis pmid:26400817
Sierra RO et al. Medial orbitofrontal cortex lesion prevents facilitatory effects of d-cycloserine during fear extinction. 2016 Behav. Brain Res. pmid:26306827
Sawant NS et al. Neuroleptic malignant syndrome in cycloserine-induced psychosis. 2015 May-Jun Indian J Pharmacol pmid:26069374
Tandon VR et al. Cycloserine induced psychosis with hepatic dysfunction. 2015 Mar-Apr Indian J Pharmacol pmid:25878391
Biswal I et al. Cedecea lapagei in a patient with malignancy: Report of a rare case. 2015 Jul-Sep J Cancer Res Ther pmid:26458603
Forsyth JK et al. Augmenting NMDA receptor signaling boosts experience-dependent neuroplasticity in the adult human brain. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:26621715
Adongo DW et al. Antidepressant-Like Effect of the Leaves of Pseudospondias microcarpa in Mice: Evidence for the Involvement of the Serotoninergic System, NMDA Receptor Complex, and Nitric Oxide Pathway. 2015 Biomed Res Int pmid:26539489
Kumagai T et al. High-Level Heterologous Production of D-Cycloserine by Escherichia coli. 2015 Appl. Environ. Microbiol. pmid:26341210
Chaturvedi SK et al. Unraveling Comparative Anti-Amyloidogenic Behavior of Pyrazinamide and D-Cycloserine: A Mechanistic Biophysical Insight. 2015 PLoS ONE pmid:26312749
Aggarwal R et al. XDR TB presenting as a transphyseal lytic lesion in the proximal tibia. 2015 BMJ Case Rep pmid:26264953
Uda N et al. The structural and mutational analyses of O-ureido-L-serine synthase necessary for D-cycloserine biosynthesis. 2015 FEBS J. pmid:26207937
Lench AM et al. Differential Effects of D-Cycloserine and ACBC at NMDA Receptors in the Rat Entorhinal Cortex Are Related to Efficacy at the Co-Agonist Binding Site. 2015 PLoS ONE pmid:26193112
Levinson CA et al. D-Cycloserine facilitation of exposure therapy improves weight regain in patients with anorexia nervosa: a pilot randomized controlled trial. 2015 J Clin Psychiatry pmid:26132687
Kuznetsov NA et al. Pre-steady-state kinetic and structural analysis of interaction of methionine γ-lyase from Citrobacter freundii with inhibitors. 2015 J. Biol. Chem. pmid:25398880
Krings JG et al. A novel treatment for tinnitus and tinnitus-related cognitive difficulties using computer-based cognitive training and D-cycloserine. 2015 JAMA Otolaryngol Head Neck Surg pmid:25356570
Sarıdoğan GE et al. D-Cycloserine acts via increasing the GluN1 protein expressions in the frontal cortex and decreases the avoidance and risk assessment behaviors in a rat traumatic stress model. 2015 Behav. Brain Res. pmid:26225843
de Kleine RA et al. Extinction learning as a moderator of d-cycloserine efficacy for enhancing exposure therapy in posttraumatic stress disorder. 2015 J Anxiety Disord pmid:26121495
Sugiyama A et al. Systemic administration of riluzole enhances recognition memory and facilitates extinction of fear memory in rats. 2015 Neuropharmacology pmid:26116528
Andersson E et al. D-Cycloserine vs Placebo as Adjunct to Cognitive Behavioral Therapy for Obsessive-Compulsive Disorder and Interaction With Antidepressants: A Randomized Clinical Trial. 2015 JAMA Psychiatry pmid:25970252
Filippi A et al. Electronic structure and conformational flexibility of D-cycloserine. 2015 Phys Chem Chem Phys pmid:25966830
Ori R et al. Augmentation of cognitive and behavioural therapies (CBT) with d-cycloserine for anxiety and related disorders. 2015 Cochrane Database Syst Rev pmid:25957940
Urbano M et al. A trial of d-cycloserine to treat the social deficit in older adolescents and young adults with autism spectrum disorders. 2015 J Neuropsychiatry Clin Neurosci pmid:25923852
Marin MF et al. Augmentation of Evidence-Based Psychotherapy for PTSD With Cognitive Enhancers. 2015 Curr Psychiatry Rep pmid:25894356
Zhou H et al. Pharmacokinetic Properties and Tolerability of Cycloserine Following Oral Administration in Healthy Chinese Volunteers: A Randomized, Open-Label, Single- and Multiple-Dose 3-Way Crossover Study. 2015 Clin Ther pmid:25869627
Byrne SP et al. D-cycloserine enhances generalization of fear extinction in children. 2015 Depress Anxiety pmid:25775435
Kiefer F et al. Effects of D-cycloserine on extinction of mesolimbic cue reactivity in alcoholism: a randomized placebo-controlled trial. 2015 Psychopharmacology (Berl.) pmid:25697860