D-cycloserine

D-cycloserine is a lipid of Polyketides (PK) class. D-cycloserine is associated with abnormalities such as Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis and Inflammatory Bowel Diseases. The involved functions are known as Cellular Infiltration, Vascular Permeability, Stimulus, antagonists and Kinase Inhibitors [MoA]. D-cycloserine often locates in Tissue membrane, Body tissue, Protoplasm, Endothelium and Cell Wall. The associated genes with D-cycloserine are Genome, serine O-sulfate, Polypeptides, alpha-aminobutyric acid, (S)-isomer and Genes, Reporter. The related lipids are Sphingolipids, Fatty Acids, Sterols, 25-hydroxycholesterol and Fatty Acids, Unsaturated.

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Introduction

To understand associated biological information of D-cycloserine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with D-cycloserine?

D-cycloserine is suspected in Tuberculosis, Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis, Inflammatory Bowel Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with D-cycloserine

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with D-cycloserine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with D-cycloserine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with D-cycloserine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with D-cycloserine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with D-cycloserine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with D-cycloserine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with D-cycloserine

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Authors Title Published Journal PubMed Link
Grassi G and Pallanti S Current and up-and-coming pharmacotherapy for obsessive-compulsive disorder in adults. 2018 Expert Opin Pharmacother pmid:30321070
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Ranjan R et al. Preparation and optimization of a dry powder for inhalation of second-line anti-tuberculosis drugs. 2018 Int J Pharm pmid:29852204
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Chen J et al. Identification of novel mutations associated with cycloserine resistance in Mycobacterium tuberculosis. 2017 J. Antimicrob. Chemother. pmid:28961957
Park S et al. Treatment outcomes of rifampin-sparing treatment in patients with pulmonary tuberculosis with rifampin-mono-resistance or rifampin adverse events: A retrospective cohort analysis. 2017 Respir Med pmid:28947041
Hofmeijer-Sevink MK et al. No Effects of D-Cycloserine Enhancement in Exposure With Response Prevention Therapy in Panic Disorder With Agoraphobia: A Double-Blind, Randomized Controlled Trial. 2017 J Clin Psychopharmacol pmid:28820746
Klass A et al. d-Cycloserine facilitates extinction learning and enhances extinction-related brain activation. 2017 Neurobiol Learn Mem pmid:28807795
Malan-Müller S et al. The role of microRNAs in the therapeutic action of D-cycloserine in a post-traumatic stress disorder animal model: an exploratory study. 2017 Psychiatr. Genet. pmid:28574862
Forsyth JK et al. Effects of Augmenting N-Methyl-D-Aspartate Receptor Signaling on Working Memory and Experience-Dependent Plasticity in Schizophrenia: An Exploratory Study Using Acute d-cycloserine. 2017 Schizophr Bull pmid:28338977
Baker KD and Richardson R Pharmacological evidence that a failure to recruit NMDA receptors contributes to impaired fear extinction retention in adolescent rats. 2017 Neurobiol Learn Mem pmid:27815216
Na ES et al. D-cycloserine improves synaptic transmission in an animal mode of Rett syndrome. 2017 PLoS ONE pmid:28813484
Bürkner PC et al. D-cycloserine augmentation of behavior therapy for anxiety and obsessive-compulsive disorders: A meta-analysis. 2017 PLoS ONE pmid:28282427
Wink LK et al. d-Cycloserine enhances durability of social skills training in autism spectrum disorder. 2017 Mol Autism pmid:28138381
Rismondo J et al. Suppressor Mutations Linking gpsB with the First Committed Step of Peptidoglycan Biosynthesis in Listeria monocytogenes. 2017 J. Bacteriol. pmid:27795316
Goff DC D-cycloserine in Schizophrenia: New Strategies for Improving Clinical Outcomes by Enhancing Plasticity. 2017 Curr Neuropharmacol pmid:26915421
Tremiño L et al. Studies on cyanobacterial protein PipY shed light on structure, potential functions, and vitamin B -dependent epilepsy. 2017 FEBS Lett. pmid:28914444
Tabuchi F et al. D-cycloserine increases the effectiveness of vancomycin against vancomycin-highly resistant Staphylococcus aureus. 2017 J. Antibiot. pmid:28588223
Sugiyama A et al. Administration of riluzole into the basolateral amygdala has an anxiolytic-like effect and enhances recognition memory in the rat. 2017 Behav. Brain Res. pmid:28359884
Saitoh A et al. Post-reexposure administration of D-cycloserine facilitates reconsolidation of contextual conditioned fear memory in rats. 2017 J Neural Transm (Vienna) pmid:28275863
Amorim Franco TM et al. Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d- and l-Cycloserine. 2017 ACS Chem. Biol. pmid:28272868
Huang Y et al. Modulating the Balance of Synaptic and Extrasynaptic NMDA Receptors Shows Positive Effects against Amyloid-β-Induced Neurotoxicity. 2017 J. Alzheimers Dis. pmid:28269783
Li C et al. [A preliminary study on the molecular characteristics of D-cycloserine resistance of ]. 2017 Zhonghua Liu Xing Bing Xue Za Zhi pmid:28231674
Mataix-Cols D et al. D-Cycloserine Augmentation of Exposure-Based Cognitive Behavior Therapy for Anxiety, Obsessive-Compulsive, and Posttraumatic Stress Disorders: A Systematic Review and Meta-analysis of Individual Participant Data. 2017 JAMA Psychiatry pmid:28122091
Tassoni R et al. Structural and functional characterization of the alanine racemase from Streptomyces coelicolor A3(2). 2017 Biochem. Biophys. Res. Commun. pmid:28042035
Takiguchi K et al. Association of schizophrenia onset age and white matter integrity with treatment effect of D-cycloserine: a randomized placebo-controlled double-blind crossover study. 2017 BMC Psychiatry pmid:28701225
Sta Maria NS et al. D-Cycloserine Restores Experience-Dependent Neuroplasticity after Traumatic Brain Injury in the Developing Rat Brain. 2017 J. Neurotrauma pmid:27931146
Shimizu S et al. Glycine-Binding Site Stimulants of NMDA Receptors Alleviate Extrapyramidal Motor Disorders by Activating the Nigrostriatal Dopaminergic Pathway. 2017 Int J Mol Sci pmid:28671605
de Leeuw AS et al. d-cycloserine addition to exposure sessions in the treatment of patients with obsessive-compulsive disorder. 2017 Eur. Psychiatry pmid:27837671
Sharp WG et al. Successful pharmacotherapy for the treatment of severe feeding aversion with mechanistic insights from cross-species neuronal remodeling. 2017 Transl Psychiatry pmid:28632204
Yates JR et al. Effects of N-methyl-D-aspartate receptor ligands on sensitivity to reinforcer magnitude and delayed reinforcement in a delay-discounting procedure. 2017 Psychopharmacology (Berl.) pmid:27837332
Ebrahimi C et al. Combining D-cycloserine with appetitive extinction learning modulates amygdala activity during recall. 2017 Neurobiol Learn Mem pmid:28512009
Goodman J et al. Enhancing and impairing extinction of habit memory through modulation of NMDA receptors in the dorsolateral striatum. 2017 Neuroscience pmid:28377177
Mao Z et al. A simplified LC-MS/MS method for rapid determination of cycloserine in small-volume human plasma using protein precipitation coupled with dilution techniques to overcome matrix effects and its application to a pharmacokinetic study. 2017 Anal Bioanal Chem pmid:28224247
Sogebi OA et al. Clinical predictors of aminoglycoside-induced ototoxicity in drug-resistant Tuberculosis patients on intensive therapy. 2017 Auris Nasus Larynx pmid:27832910
Olden M et al. Pilot Study of a Telehealth-Delivered Medication-Augmented Exposure Therapy Protocol for PTSD. 2017 J. Nerv. Ment. Dis. pmid:27441461
McGuire JF et al. A Meta-Analysis of D-Cycloserine in Exposure-Based Treatment: Moderators of Treatment Efficacy, Response, and Diagnostic Remission. 2017 J Clin Psychiatry pmid:27314661
Kantrowitz JT et al. d-Cycloserine, an NMDA Glutamate Receptor Glycine Site Partial Agonist, Induces Acute Increases in Brain Glutamate Plus Glutamine and GABA Comparable to Ketamine. 2016 Am J Psychiatry pmid:27903101
Goff D The Therapeutic Role of d-Cycloserine in Schizophrenia. 2016 Adv. Pharmacol. pmid:27288073
Otto MW et al. Examining the efficacy of d-cycloserine to augment therapeutic learning in depression. 2016 Contemp Clin Trials pmid:27094721
Yu X et al. Sensititre® MYCOTB MIC plate for drug susceptibility testing of Mycobacterium tuberculosis complex isolates. 2016 Int. J. Tuberc. Lung Dis. pmid:27046713
Smits JA et al. Enhancing panic and smoking reduction treatment with d-cycloserine: Study protocol for a randomized controlled trial. 2016 Contemp Clin Trials pmid:27015966
Fang A and Wilhelm S Antidepressant use with d-Cycloserine may block fear extinction. 2016 Evid Based Ment Health pmid:26792833