D-cycloserine

D-cycloserine is a lipid of Polyketides (PK) class. D-cycloserine is associated with abnormalities such as Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis and Inflammatory Bowel Diseases. The involved functions are known as Cellular Infiltration, Vascular Permeability, Stimulus, antagonists and Kinase Inhibitors [MoA]. D-cycloserine often locates in Tissue membrane, Body tissue, Protoplasm, Endothelium and Cell Wall. The associated genes with D-cycloserine are Genome, serine O-sulfate, Polypeptides, alpha-aminobutyric acid, (S)-isomer and Genes, Reporter. The related lipids are Sphingolipids, Fatty Acids, Sterols, 25-hydroxycholesterol and Fatty Acids, Unsaturated.

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Introduction

To understand associated biological information of D-cycloserine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with D-cycloserine?

D-cycloserine is suspected in Tuberculosis, Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis, Inflammatory Bowel Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with D-cycloserine

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with D-cycloserine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with D-cycloserine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with D-cycloserine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with D-cycloserine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with D-cycloserine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with D-cycloserine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with D-cycloserine

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Authors Title Published Journal PubMed Link
Yang FY et al. D-cycloserine, sarcosine and D-serine diminish the expression of cocaine-induced conditioned place preference. 2013 J. Psychopharmacol. (Oxford) pmid:21106609
Price KL et al. A randomized, placebo-controlled laboratory study of the effects of D-cycloserine on craving in cocaine-dependent individuals. 2013 Psychopharmacology (Berl.) pmid:22234379
Yoon JH et al. Effects of D-cycloserine on cue-induced craving and cigarette smoking among concurrent cocaine- and nicotine-dependent volunteers. 2013 Addict Behav pmid:22560371
Horio M et al. Is D-cycloserine a prodrug for D-serine in the brain? 2013 Biol. Psychiatry pmid:22877923
Leslie JC and Norwood K Facilitation of extinction and re-extinction of operant behavior in mice by chlordiazepoxide and D-cycloserine. 2013 Neurobiol Learn Mem pmid:23416058
Maimakov T et al. Treatment of tuberculosis in South Kazakhstan: clinical and economical aspects. 2013 Medicina (Kaunas) pmid:24375246
Smits JA et al. D-cycloserine augmentation of cognitive behavioral group therapy of social anxiety disorder: prognostic and prescriptive variables. 2013 J Consult Clin Psychol pmid:23937345
Kranjac D et al. Peripheral administration of D-cycloserine rescues memory consolidation following bacterial endotoxin exposure. 2013 Behav. Brain Res. pmid:23295393
Rodebaugh TL et al. A high-throughput clinical assay for testing drug facilitation of exposure therapy. 2013 Depress Anxiety pmid:23283838
Prosser GA and de Carvalho LP Kinetic mechanism and inhibition of Mycobacterium tuberculosis D-alanine:D-alanine ligase by the antibiotic D-cycloserine. 2013 FEBS J. pmid:23286234
Portero-Tresserra M et al. D-cycloserine in the basolateral amygdala prevents extinction and enhances reconsolidation of odor-reward associative learning in rats. 2013 Neurobiol Learn Mem pmid:23200640
Oda K et al. Crystallographic study to determine the substrate specificity of an L-serine-acetylating enzyme found in the D-cycloserine biosynthetic pathway. 2013 J. Bacteriol. pmid:23396912
Wei AC et al. A facile three-component [3+2]-cycloaddition for the regioselective synthesis of highly functionalised dispiropyrrolidines acting as antimycobacterial agents. 2013 Bioorg. Med. Chem. Lett. pmid:23352268
Smits JA et al. D-cycloserine enhancement of fear extinction is specific to successful exposure sessions: evidence from the treatment of height phobia. 2013 Biol. Psychiatry pmid:23332511
Baisa G et al. Characterization of Escherichia coli D-cycloserine transport and resistant mutants. 2013 J. Bacteriol. pmid:23316042
Saito Y et al. Facilitation of fear extinction by the 5-HT(1A) receptor agonist tandospirone: possible involvement of dopaminergic modulation. 2013 Synapse pmid:23152167
Peters J and De Vries TJ D-cycloserine administered directly to infralimbic medial prefrontal cortex enhances extinction memory in sucrose-seeking animals. 2013 Neuroscience pmid:23159319
Heresco-Levy U et al. A randomized add-on trial of high-dose D-cycloserine for treatment-resistant depression. 2013 Int. J. Neuropsychopharmacol. pmid:23174090
Villarejo-Rodríguez I et al. Learning deficits in an odor reward-task induced by parafascicular thalamic lesions are ameliorated by pretraining D-cycloserine in the prelimbic cortex. 2013 Behav. Brain Res. pmid:23124092
Tart CD et al. Augmentation of exposure therapy with post-session administration of D-cycloserine. 2013 J Psychiatr Res pmid:23098672
Van der Walt M et al. Serious treatment related adverse drug reactions amongst anti-retroviral naïve MDR-TB patients. 2013 PLoS ONE pmid:23573193
Carson KC et al. Isolation of Clostridium difficile from faecal specimens--a comparison of chromID C. difficile agar and cycloserine-cefoxitin-fructose agar. 2013 J. Med. Microbiol. pmid:23579394
Moridani M and Scott T Lookalike, soundalike tests: preventing serious medical errors. 2013 Arch. Pathol. Lab. Med. pmid:23276168
Uda N et al. Establishment of an in vitro D-cycloserine-synthesizing system by using O-ureido-L-serine synthase and D-cycloserine synthetase found in the biosynthetic pathway. 2013 Antimicrob. Agents Chemother. pmid:23529730
Benson AD et al. Balb/c mice treated with D-cycloserine arouse increased social interest in conspecifics. 2013 Brain Res. Bull. pmid:24157954
Smits JA et al. D-cycloserine enhancement of exposure therapy for social anxiety disorder depends on the success of exposure sessions. 2013 J Psychiatr Res pmid:23870811
Preuss J et al. Characterization of tryptophan aminotransferase 1 of Malassezia furfur, the key enzyme in the production of indolic compounds by M. furfur. 2013 Exp. Dermatol. pmid:24118363
Prosser GA and de Carvalho LP Metabolomics Reveal d-Alanine:d-Alanine Ligase As the Target of d-Cycloserine in Mycobacterium tuberculosis. 2013 ACS Med Chem Lett pmid:24478820
Sukhanov DS et al. [Pharmacological activity of runihol and S-adenosyl-L-methionine in rats with experimental liver damage by reserve antituberculosis drugs]. 2013 Eksp Klin Farmakol pmid:24432566
Rapp A et al. Treatment of pediatric anxiety disorders. 2013 Ann. N. Y. Acad. Sci. pmid:24279893
Hwang CH et al. Chlorinated coumarins from the polypore mushroom Fomitopsis officinalis and their activity against Mycobacterium tuberculosis. 2013 J. Nat. Prod. pmid:24087924
Zalta AK et al. Sleep quality predicts treatment outcome in CBT for social anxiety disorder. 2013 Depress Anxiety pmid:24038728
Shakya N et al. Discovery of novel 5-(ethyl or hydroxymethyl) analogs of 2'-'up' fluoro (or hydroxyl) pyrimidine nucleosides as a new class of Mycobacterium tuberculosis, Mycobacterium bovis and Mycobacterium avium inhibitors. 2012 Bioorg. Med. Chem. pmid:22664188
Leslie JC et al. Facilitation of extinction of operant behaviour in C57Bl/6 mice by chlordiazepoxide and D-cycloserine. 2012 Psychopharmacology (Berl.) pmid:22526539
Hofmann SG et al. D-cycloserine as an augmentation strategy for cognitive behavioral therapy for anxiety disorders: an update. 2012 Curr. Pharm. Des. pmid:22632472
Kumagai T et al. Heme protein and hydroxyarginase necessary for biosynthesis of D-cycloserine. 2012 Antimicrob. Agents Chemother. pmid:22547619
Bharath SR et al. Structural and mutational studies on substrate specificity and catalysis of Salmonella typhimurium D-cysteine desulfhydrase. 2012 PLoS ONE pmid:22574144
Kennedy AP et al. A controlled trial of the adjunct use of D-cycloserine to facilitate cognitive behavioral therapy outcomes in a cocaine-dependent population. 2012 Addict Behav pmid:22578380
Bontempo A et al. D-cycloserine augmentation of behavioral therapy for the treatment of anxiety disorders: a meta-analysis. 2012 J Clin Psychiatry pmid:22579153
Krystal JH Enhancing prolonged exposure therapy for posttraumatic stress disorder with D-cycloserine: further support for treatments that promote experience-dependent neuroplasticity. 2012 Biol. Psychiatry pmid:22579302
Myers KM and Carlezon WA D-cycloserine effects on extinction of conditioned responses to drug-related cues. 2012 Biol. Psychiatry pmid:22579305
Dubrovina NI [Fear memory extinction accelerated by simultaneous activation of GABA(B) and NMDA receptors]. 2012 Eksp Klin Farmakol pmid:22550851
Adler J Erasing painful memories. 2012 Sci. Am. pmid:22550927
Foster NF and Riley TV Improved recovery of Clostridium difficile spores with the incorporation of synthetic taurocholate in cycloserine-cefoxitin-fructose agar (CCFA). 2012 Pathology pmid:22531346
Shin KO et al. Terpene alcohols inhibit de novo sphingolipid biosynthesis. 2012 Planta Med. pmid:22274813
Dietrich D et al. Characterization of DcsC, a PLP-independent racemase involved in the biosynthesis of D-cycloserine. 2012 Org. Biomol. Chem. pmid:22307920
Deutsch SI et al. D-cycloserine improves sociability and spontaneous stereotypic behaviors in 4-week old mice. 2012 Brain Res. pmid:22261249
Gutner CA et al. The effect of D-cycloserine on subliminal cue exposure in spider fearful individuals. 2012 Cogn Behav Ther pmid:22992160
Chen JM et al. A point mutation in cycA partially contributes to the D-cycloserine resistance trait of Mycobacterium bovis BCG vaccine strains. 2012 PLoS ONE pmid:22912881
Kalechstein AD et al. d-Cycloserine administration does not affect neurocognition in concurrent cocaine- and nicotine-dependent volunteers. 2012 Pharmacol. Biochem. Behav. pmid:22960612
Normann C et al. Neuroenhancement strategies for psychiatric disorders: rationale, status quo and perspectives. 2012 Eur Arch Psychiatry Clin Neurosci pmid:22932721
Tian WX et al. Copper as an antimicrobial agent against opportunistic pathogenic and multidrug resistant Enterobacter bacteria. 2012 J. Microbiol. pmid:22923106
Baker KD et al. D-cycloserine does not facilitate fear extinction by reducing conditioned stimulus processing or promoting conditioned inhibition to contextual cues. 2012 Learn. Mem. pmid:22984284
Diacon AH et al. Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance. 2012 Antimicrob. Agents Chemother. pmid:22391540
Vloet TD et al. [Psychotherapeutic and pharmacological treatment of pediatric obsessive-compulsive disorder]. 2012 Z Kinder Jugendpsychiatr Psychother pmid:22161940
Aldridge BB et al. Asymmetry and aging of mycobacterial cells lead to variable growth and antibiotic susceptibility. 2012 Science pmid:22174129
Ozawa T et al. D-Cycloserine enhances spatial memory in spontaneous place recognition in rats. 2012 Neurosci. Lett. pmid:22215115
Das RK and Kamboj SK Maintaining clinical relevance: considerations for the future of research into D-cycloserine and cue exposure therapy for addiction. 2012 Biol. Psychiatry pmid:22748617
de Kleine RA et al. A randomized placebo-controlled trial of D-cycloserine to enhance exposure therapy for posttraumatic stress disorder. 2012 Biol. Psychiatry pmid:22480663
Pesek JJ et al. Analysis of cycloserine and related compounds using aqueous normal phase chromatography/mass spectrometry. 2012 J Pharm Biomed Anal pmid:22424861
Shrivastava AK et al. alr0882 encoding a hypothetical protein of Anabaena PCC7120 protects Escherichia coli from nutrient starvation and abiotic stresses. 2012 Gene pmid:23006586
Kopinc R and Lapanje A Antibiotic susceptibility profile of Mycobacterium avium subspecies hominissuis is altered in low-iron conditions. 2012 J. Antimicrob. Chemother. pmid:22872445
Goff DC D-cycloserine: an evolving role in learning and neuroplasticity in schizophrenia. 2012 Schizophr Bull pmid:22368237
Wang CH et al. Possible cage-like nanostructures formed by amino acids. 2012 Org. Biomol. Chem. pmid:22618243
Litz BT et al. A randomized placebo-controlled trial of D-cycloserine and exposure therapy for posttraumatic stress disorder. 2012 J Psychiatr Res pmid:22694905
Lowther J et al. Structural, mechanistic and regulatory studies of serine palmitoyltransferase. 2012 Biochem. Soc. Trans. pmid:22616865
Won H et al. Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function. 2012 Nature pmid:22699620
Carroll MW et al. Frequency of adverse reactions to first- and second-line anti-tuberculosis chemotherapy in a Korean cohort. 2012 Int. J. Tuberc. Lung Dis. pmid:22584241
Stříbrný J et al. GC/MS determination of ibotenic acid and muscimol in the urine of patients intoxicated with Amanita pantherina. 2012 Int. J. Legal Med. pmid:21751026
Ford-Green J et al. Evaluation of natural and nitramine binding energies to 3-D models of the S1S2 domains in the N-methyl-D-aspartate receptor. 2012 J Mol Model pmid:21735122
Kochlamazashvili G et al. Restoration of synaptic plasticity and learning in young and aged NCAM-deficient mice by enhancing neurotransmission mediated by GluN2A-containing NMDA receptors. 2012 J. Neurosci. pmid:22396402
Klumpers F et al. Testing the effects of Δ9-THC and D-cycloserine on extinction of conditioned fear in humans. 2012 J. Psychopharmacol. (Oxford) pmid:22351380
Paquette MA et al. Anti-dyskinetic mechanisms of amantadine and dextromethorphan in the 6-OHDA rat model of Parkinson's disease: role of NMDA vs. 5-HT1A receptors. 2012 Eur. J. Neurosci. pmid:22861201
Pawlak CR et al. Potential of D-cycloserine in the treatment of behavioral and neuroinflammatory disorders in Parkinson's disease and studies that need to be performed before clinical trials. 2012 Kaohsiung J. Med. Sci. pmid:22892161
Heeg D et al. Spores of Clostridium difficile clinical isolates display a diverse germination response to bile salts. 2012 PLoS ONE pmid:22384234
Nikitin VP and Solntseva SV Mechanisms of amnesia induced by impairment of long-term memory reconsolidation in edible snail. 2012 Bull. Exp. Biol. Med. pmid:23113237
Kant S et al. Extra-pulmonary primary multidrug-resistant tubercular lymphadenitis in an HIV negative patient. 2012 BMJ Case Rep pmid:22605844
Nave AM et al. Exposure therapy, D-cycloserine, and functional magnetic resonance imaging in patients with snake phobia: a randomized pilot study. 2012 J Clin Psychiatry pmid:23059145
Ylilauri M and Pentikäinen OT Structural mechanism of N-methyl-D-aspartate receptor type 1 partial agonism. 2012 PLoS ONE pmid:23077649
Fullam E et al. Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme. 2012 Open Biol pmid:22645655
Satti H et al. Outcomes of comprehensive care for children empirically treated for multidrug-resistant tuberculosis in a setting of high HIV prevalence. 2012 PLoS ONE pmid:22629356
Kamboj SK et al. Cue exposure and response prevention with heavy smokers: a laboratory-based randomised placebo-controlled trial examining the effects of D-cycloserine on cue reactivity and attentional bias. 2012 Psychopharmacology (Berl.) pmid:22101394
Chhabra N et al. Pharmacotherapy for multidrug resistant tuberculosis. 2012 J Pharmacol Pharmacother pmid:22629081
Da Costa CF et al. Synthesis and antitubercular activity of novel amino acid derivatives. 2012 Chem Biol Drug Des pmid:22078007
Prasad R Multidrug and extensively drug-resistant tuberculosis management: Evidences and controversies. 2012 Lung India pmid:22628931
Luyirika E et al. A home-based approach to managing multi-drug resistant tuberculosis in Uganda: a case report. 2012 AIDS Res Ther pmid:22524486
Hofmann SG et al. Effects of D-cycloserine on craving to alcohol cues in problem drinkers: preliminary findings. 2012 Am J Drug Alcohol Abuse pmid:21851195
Jain AK et al. Tuberculosis spine: Therapeutically refractory disease. 2012 Indian J Orthop pmid:22448055
Valsalan R et al. Efficacy of directly observed treatment short-course intermittent regimen in spinal tuberculosis. 2012 Indian J Orthop pmid:22448050
Shenoi SV et al. Survival from XDR-TB is associated with modifiable clinical characteristics in rural South Africa. 2012 PLoS ONE pmid:22412840
Lynn MM et al. Troublesome Tuberculosis: A Case Report on Multi-focal Tuberculous Osteomyelitis in An Immunocompetent Patient. 2012 J Clin Med Res pmid:22383933
Mickley GA et al. Acute, but not chronic, exposure to d-cycloserine facilitates extinction and modulates spontaneous recovery of a conditioned taste aversion. 2012 Physiol. Behav. pmid:21925192
Dholakia YN Ethics, human rights and programmatic management of drug-resistant tuberculosis. 2012 Lung India pmid:22345934
Ray K Trends in tropical medicine research in India. 2012 Indian J Pharmacol pmid:22345860
Godreuil S et al. Mycobacterium riyadhense pulmonary infection, France and Bahrain. 2012 Emerging Infect. Dis. pmid:22261434
Arvand M et al. High prevalence of Clostridium difficile colonization among nursing home residents in Hesse, Germany. 2012 PLoS ONE pmid:22253917
Loto OM and Awowole I Tuberculosis in pregnancy: a review. 2012 J Pregnancy pmid:22132339
Dembek M et al. Clostridium difficile cell wall protein CwpV undergoes enzyme-independent intramolecular autoproteolysis. 2012 J. Biol. Chem. pmid:22128177
Kulichevskaya IS et al. Telmatocola sphagniphila gen. nov., sp. nov., a novel dendriform planctomycete from northern wetlands. 2012 Front Microbiol pmid:22529844
Sarkar S and Sood M A patient of multidrug-resistant tuberculosis on category IV treatment regimen presenting with psychosis. 2011 Jul-Aug Natl Med J India pmid:22208150