D-cycloserine

D-cycloserine is a lipid of Polyketides (PK) class. D-cycloserine is associated with abnormalities such as Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis and Inflammatory Bowel Diseases. The involved functions are known as Cellular Infiltration, Vascular Permeability, Stimulus, antagonists and Kinase Inhibitors [MoA]. D-cycloserine often locates in Tissue membrane, Body tissue, Protoplasm, Endothelium and Cell Wall. The associated genes with D-cycloserine are Genome, serine O-sulfate, Polypeptides, alpha-aminobutyric acid, (S)-isomer and Genes, Reporter. The related lipids are Sphingolipids, Fatty Acids, Sterols, 25-hydroxycholesterol and Fatty Acids, Unsaturated.

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Introduction

To understand associated biological information of D-cycloserine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with D-cycloserine?

D-cycloserine is suspected in Tuberculosis, Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis, Inflammatory Bowel Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with D-cycloserine

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with D-cycloserine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with D-cycloserine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with D-cycloserine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with D-cycloserine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with D-cycloserine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with D-cycloserine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with D-cycloserine

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Authors Title Published Journal PubMed Link
Klass A et al. d-Cycloserine facilitates extinction learning and enhances extinction-related brain activation. 2017 Neurobiol Learn Mem pmid:28807795
Malan-Müller S et al. The role of microRNAs in the therapeutic action of D-cycloserine in a post-traumatic stress disorder animal model: an exploratory study. 2017 Psychiatr. Genet. pmid:28574862
Forsyth JK et al. Effects of Augmenting N-Methyl-D-Aspartate Receptor Signaling on Working Memory and Experience-Dependent Plasticity in Schizophrenia: An Exploratory Study Using Acute d-cycloserine. 2017 Schizophr Bull pmid:28338977
Olden M et al. Pilot Study of a Telehealth-Delivered Medication-Augmented Exposure Therapy Protocol for PTSD. 2017 J. Nerv. Ment. Dis. pmid:27441461
Kim SW et al. Low-Dose d-Cycloserine for Depression? 2016 J Clin Psychiatry pmid:27561144
Hofmann SG Schrödinger's Cat and d-Cycloserine to Augment Exposure Therapy-Both Are Alive and Dead. 2016 JAMA Psychiatry pmid:27367470
Kantrowitz JT et al. d-Cycloserine, an NMDA Glutamate Receptor Glycine Site Partial Agonist, Induces Acute Increases in Brain Glutamate Plus Glutamine and GABA Comparable to Ketamine. 2016 Am J Psychiatry pmid:27903101
Schnitzer TJ et al. A randomized placebo-controlled pilot study of the efficacy and safety of D-cycloserine in people with chronic back pain. 2016 Mol Pain pmid:27852965
Kapolowicz MR and Thompson LT Acute high-intensity noise induces rapid Arc protein expression but fails to rapidly change GAD expression in amygdala and hippocampus of rats: Effects of treatment with D-cycloserine. 2016 Hear. Res. pmid:27702572
Eniyan K et al. Development of a one-pot assay for screening and identification of Mur pathway inhibitors in Mycobacterium tuberculosis. 2016 Sci Rep pmid:27734910
Günthner J et al. The NMDA receptor partial agonist d-cycloserine does not enhance motor learning. 2016 J. Psychopharmacol. (Oxford) pmid:27436230
Liraz-Zaltsman S et al. Neuroinflammation-Induced Memory Deficits Are Amenable to Treatment with D-Cycloserine. 2016 J. Mol. Neurosci. pmid:27421842
Storch EA et al. Efficacy of Augmentation of Cognitive Behavior Therapy With Weight-Adjusted d-Cycloserine vs Placebo in Pediatric Obsessive-Compulsive Disorder: A Randomized Clinical Trial. 2016 JAMA Psychiatry pmid:27367832
Otto MW et al. RANDOMIZED TRIAL OF D-CYCLOSERINE ENHANCEMENT OF COGNITIVE-BEHAVIORAL THERAPY FOR PANIC DISORDER. 2016 Depress Anxiety pmid:27315514
Goff D The Therapeutic Role of d-Cycloserine in Schizophrenia. 2016 Adv. Pharmacol. pmid:27288073
Otto MW et al. Examining the efficacy of d-cycloserine to augment therapeutic learning in depression. 2016 Contemp Clin Trials pmid:27094721
Yu X et al. Sensititre® MYCOTB MIC plate for drug susceptibility testing of Mycobacterium tuberculosis complex isolates. 2016 Int. J. Tuberc. Lung Dis. pmid:27046713
Smits JA et al. Enhancing panic and smoking reduction treatment with d-cycloserine: Study protocol for a randomized controlled trial. 2016 Contemp Clin Trials pmid:27015966
Fang A and Wilhelm S Antidepressant use with d-Cycloserine may block fear extinction. 2016 Evid Based Ment Health pmid:26792833
Qiu W et al. d-Alanine metabolism is essential for growth and biofilm formation of Streptococcus mutans. 2016 Mol Oral Microbiol pmid:26526529