D-cycloserine

D-cycloserine is a lipid of Polyketides (PK) class. D-cycloserine is associated with abnormalities such as Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis and Inflammatory Bowel Diseases. The involved functions are known as Cellular Infiltration, Vascular Permeability, Stimulus, antagonists and Kinase Inhibitors [MoA]. D-cycloserine often locates in Tissue membrane, Body tissue, Protoplasm, Endothelium and Cell Wall. The associated genes with D-cycloserine are Genome, serine O-sulfate, Polypeptides, alpha-aminobutyric acid, (S)-isomer and Genes, Reporter. The related lipids are Sphingolipids, Fatty Acids, Sterols, 25-hydroxycholesterol and Fatty Acids, Unsaturated.

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Introduction

To understand associated biological information of D-cycloserine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with D-cycloserine?

D-cycloserine is suspected in Tuberculosis, Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis, Inflammatory Bowel Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with D-cycloserine

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with D-cycloserine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with D-cycloserine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with D-cycloserine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with D-cycloserine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with D-cycloserine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with D-cycloserine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with D-cycloserine

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Authors Title Published Journal PubMed Link
Levinson CA et al. D-Cycloserine facilitation of exposure therapy improves weight regain in patients with anorexia nervosa: a pilot randomized controlled trial. 2015 J Clin Psychiatry pmid:26132687
Iosifescu DV Maintaining the initial clinical response after ketamine in bipolar and unipolar depression: an important next-step challenge. 2015 J Clin Psychiatry pmid:26132676
Kantrowitz JT et al. Single-dose ketamine followed by daily D-Cycloserine in treatment-resistant bipolar depression. 2015 J Clin Psychiatry pmid:26132675
Hofmann SG et al. Dose timing of D-cycloserine to augment cognitive behavioral therapy for social anxiety: Study design and rationale. 2015 Contemp Clin Trials pmid:26111923
Lee SH et al. Low Serum Concentrations of Moxifloxacin, Prothionamide, and Cycloserine on Sputum Conversion in Multi-Drug Resistant TB. 2015 Yonsei Med. J. pmid:26069117
Park SI et al. Pharmacokinetics of Second-Line Antituberculosis Drugs after Multiple Administrations in Healthy Volunteers. 2015 Antimicrob. Agents Chemother. pmid:25987620
Xia J et al. D-cycloserine augmentation in behavioral therapy for obsessive-compulsive disorder: a meta-analysis. 2015 Drug Des Devel Ther pmid:25960632
Hawkins-Salsbury JA et al. Mechanism-based combination treatment dramatically increases therapeutic efficacy in murine globoid cell leukodystrophy. 2015 J. Neurosci. pmid:25904800
Scofield MD et al. Failure to Recognize Novelty after Extended Methamphetamine Self-Administration Results from Loss of Long-Term Depression in the Perirhinal Cortex. 2015 Neuropsychopharmacology pmid:25865928
MacKillop J et al. D-cycloserine to enhance extinction of cue-elicited craving for alcohol: a translational approach. 2015 Transl Psychiatry pmid:25849983
Santa Ana EJ et al. D-cycloserine combined with cue exposure therapy fails to attenuate subjective and physiological craving in cocaine dependence. 2015 Am J Addict pmid:25808169
Seif T et al. D-Serine and D-Cycloserine Reduce Compulsive Alcohol Intake in Rats. 2015 Neuropsychopharmacology pmid:25801502
Fillmore N et al. Accumulation of ceramide in slow-twitch muscle contributes to the development of insulin resistance in the obese JCR:LA-cp rat. 2015 Exp. Physiol. pmid:25786668
Brom M et al. d-Cycloserine reduces context specificity of sexual extinction learning. 2015 Neurobiol Learn Mem pmid:26456134
Vishnoi S et al. Modulatory effects of an NMDAR partial agonist in MK-801-induced memory impairment. 2015 Neuroscience pmid:26454025
Furlow B Public outcry over US generic drug price hikes. 2015 Lancet Respir Med pmid:26453140
Olatunji BO et al. EFFECTS OF HOMEWORK COMPLIANCE ON COGNITIVE-BEHAVIORAL THERAPY WITH D-CYCLOSERINE AUGMENTATION FOR CHILDREN WITH OBSESSIVE COMPULSIVE DISORDER. 2015 Depress Anxiety pmid:26372401
Kiefer F et al. Effects of D-cycloserine on extinction of mesolimbic cue reactivity in alcoholism: a randomized placebo-controlled trial. 2015 Psychopharmacology (Berl.) pmid:25697860
Philbert J et al. The CRF₁ receptor antagonist SSR125543 prevents stress-induced long-lasting sleep disturbances in a mouse model of PTSD: comparison with paroxetine and d-cycloserine. 2015 Behav. Brain Res. pmid:25446760
Hofmann SG et al. D-cycloserine augmentation of cognitive behavioral therapy for anxiety disorders: an update. 2015 Curr Psychiatry Rep pmid:25413638