D-cycloserine

D-cycloserine is a lipid of Polyketides (PK) class. D-cycloserine is associated with abnormalities such as Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis and Inflammatory Bowel Diseases. The involved functions are known as Cellular Infiltration, Vascular Permeability, Stimulus, antagonists and Kinase Inhibitors [MoA]. D-cycloserine often locates in Tissue membrane, Body tissue, Protoplasm, Endothelium and Cell Wall. The associated genes with D-cycloserine are Genome, serine O-sulfate, Polypeptides, alpha-aminobutyric acid, (S)-isomer and Genes, Reporter. The related lipids are Sphingolipids, Fatty Acids, Sterols, 25-hydroxycholesterol and Fatty Acids, Unsaturated.

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Introduction

To understand associated biological information of D-cycloserine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with D-cycloserine?

D-cycloserine is suspected in Tuberculosis, Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis, Inflammatory Bowel Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with D-cycloserine

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with D-cycloserine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with D-cycloserine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with D-cycloserine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with D-cycloserine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with D-cycloserine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with D-cycloserine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with D-cycloserine

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Authors Title Published Journal PubMed Link
Deutsch SI et al. Stress and a glycinergic intervention interact in the modulation of MK-801-elicited mouse popping behavior. 1999 Pharmacol. Biochem. Behav. pmid:9972709
Goff DC et al. A placebo-controlled trial of D-cycloserine added to conventional neuroleptics in patients with schizophrenia. 1999 Arch. Gen. Psychiatry pmid:9892252
Farber NB et al. Glycine agonists: what can they teach us about schizophrenia? 1999 Arch. Gen. Psychiatry pmid:9892251
Williams SL et al. Development of a firefly luciferase-based assay for determining antimicrobial susceptibility of Mycobacterium avium subsp. paratuberculosis. 1999 J. Clin. Microbiol. pmid:9889208
Kishi A et al. Concurrent activation of hippocampal glycine and polyamine sites of the N-methyl-D-aspartate receptor synergistically reverses working memory deficits in rats. 1998 Neurosci. Lett. pmid:9870337
Riekkinen P et al. D-cycloserine, a partial NMDA receptor-associated glycine-B site agonist, enhances reversal learning, but a cholinesterase inhibitor and nicotine has no effect. 1998 Neuroreport pmid:9858374
Kawabe K et al. Intrahippocampal D-cycloserine improves MK-801-induced memory deficits: radial-arm maze performance in rats. 1998 Brain Res. pmid:9838131
Semba J [Glycine therapy of schizophrenia; its rationale and a review of clinical trials]. 1998 Nihon Shinkei Seishin Yakurigaku Zasshi pmid:9800198
Saigoh K et al. The stereo-specific effect of D-serine ethylester and the D-cycloserine in ataxic mutant mice. 1998 Brain Res. pmid:9795125
Leppimäki P et al. The rate of sphingomyelin synthesis de novo is influenced by the level of cholesterol in cultured human skin fibroblasts. 1998 Biochem. J. pmid:9761725