Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Uterine Hemorrhage | D014592 | 6 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jensen JM et al. | Gene expression is differently affected by pimecrolimus and betamethasone in lesional skin of atopic dermatitis. | 2012 | Allergy | pmid:22142306 |
| Gökçe M et al. | Left ventricular diastolic function assessment by tissue Doppler echocardiography in relation to hormonal replacement therapy in postmenopausal women with diastolic dysfunction. | Am J Ther | pmid:12629588 | |
| Bryant BP and Moore PA | Factors affecting the sensitivity of the lingual trigeminal nerve to acids. | 1995 | Am. J. Physiol. | pmid:7840339 |
| Guggino SE et al. | Specificity and modes of the anion exchanger in dog renal microvillus membranes. | 1983 | Am. J. Physiol. | pmid:6859253 |
| Andriamihaja M et al. | Colon luminal content and epithelial cell morphology are markedly modified in rats fed with a high-protein diet. | 2010 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:20689060 |
| Manni L et al. | Effect of anti-NGF on ovarian expression of alpha1- and beta2-adrenoceptors, TrkA, p75NTR, and tyrosine hydroxylase in rats with steroid-induced polycystic ovaries. | 2006 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:16195501 |
| Andrews FM et al. | In vitro effects of hydrochloric acid and various concentrations of acetic, propionic, butyric, or valeric acids on bioelectric properties of equine gastric squamous mucosa. | 2006 | Am. J. Vet. Res. | pmid:17078749 |
| Nadeau JA et al. | Effects of hydrochloric, valeric, and other volatile fatty acids on pathogenesis of ulcers in the nonglandular portion of the stomach of horses. | 2003 | Am. J. Vet. Res. | pmid:12693529 |
| Eggink M et al. | Targeted LC-MS derivatization for aldehydes and carboxylic acids with a new derivatization agent 4-APEBA. | 2010 | Anal Bioanal Chem | pmid:20238107 |
| Tomcik K et al. | Isotopomer enrichment assay for very short chain fatty acids and its metabolic applications. | 2011 | Anal. Biochem. | pmid:21112315 |