Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Uterine Hemorrhage | D014592 | 6 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Weber G | Letter: The treatment of cavernous haemangioma with topical betamethasone 17 valerate. | 1973 | Br. J. Dermatol. | pmid:4802519 |
| Baisden LA et al. | n-Valeric acid in stomachs and on unwashed hair of swine. | 1972 | J. Anim. Sci. | pmid:5039919 |
| Babenko GA and Vandzhura IP | [Use of zinc valerate in the complex treatment of ischemic disease]. | 1971 | Vrach Delo | pmid:5143053 |
| Nielsen FH et al. | Changes in serum lipids during treatment with norgestrel, oestradiol-valerate and cycloprogynon. | 1977 | Acta Obstet Gynecol Scand | pmid:602705 |
| Perkins MN et al. | Phosphonate analogues of carboxylic acids as aminoacid antagonists on rat cortical neurones. | 1981 | Neurosci. Lett. | pmid:6115343 |
| Ishizawa H et al. | Effects of betamethasone 17 valerate on the cyclic AMP system of the pig skin epidermis. | 1983 | J. Dermatol. | pmid:6321577 |
| Vilska S et al. | Long-term post-menopausal hormone therapy and serum HDL-C, total cholesterol and triglycerides. | 1983 | Maturitas | pmid:6415365 |
| Perlman BJ and Goldstein DB | Membrane-disordering potency and anticonvulsant action of valproic acid and other short-chain fatty acids. | 1984 | Mol. Pharmacol. | pmid:6431262 |
| Verschoyle RD et al. | The toxicity and neuropathology of 2,4,5-tribromoimidazole and its derivatives in rats. | 1984 | Arch. Toxicol. | pmid:6532374 |
| Stone TW | Excitant activity of methyl derivatives of quinolinic acid on rat cortical neurones. | 1984 | Br. J. Pharmacol. | pmid:6546701 |
| Woodworth JR et al. | Quantitative analysis of phencyclidine and metabolites by capillary column gas chromatography. | 1984 Jan-Feb | J Anal Toxicol | pmid:6708471 |
| Abdel-Monem MM and Mikhail EA | Inhibitors of polyamine biosynthesis VI: 2,5-Diamino-2-(cyanomethyl) pentanoic acid, a potential irreversible inhibitor of ornithine decarboxylase. | 1978 | J Pharm Sci | pmid:671262 |
| Guggino SE et al. | Specificity and modes of the anion exchanger in dog renal microvillus membranes. | 1983 | Am. J. Physiol. | pmid:6859253 |
| Borenstein DG et al. | Gas-liquid chromatographic analysis of synovial fluid: volatile short-chain fatty acids in septic arthritis. | 1983 | Ann. Rheum. Dis. | pmid:6882030 |
| Maizel' EB et al. | [Ephedrine, salsoline and cytisine derivatives as substrates and inhibitirs of cholinesterases]. | 1978 | Biokhimiia | pmid:698301 |
| Shimo T et al. | [Irritation test of dexamethasone valerate (DV-17) and other steroid ointments in rabbits. Skin and eye primary irritation tests, and skin cumulative irritation test]. | 1982 | J Toxicol Sci | pmid:7154133 |
| Shimo T et al. | [Comparative toxicity test of dexamethasone valerate (DV-17) and other steroid ointments in rats]. | 1982 | J Toxicol Sci | pmid:7154134 |
| Brown NA et al. | Chain length dependency of fatty acid and carbamate binding to serum albumin. | 1982 | Biochem. Pharmacol. | pmid:7159478 |
| Chang SC and Lee VH | Influence of chain length on the in vitro hydrolysis of model ester prodrugs by ocular esterases. | 1982-1983 | Curr. Eye Res. | pmid:7186434 |
| Felix A et al. | Effect of feeding isoacids with urea on growth and nutrient utilization by lactating cows. | 1980 | J. Dairy Sci. | pmid:7192295 |
| Yen PM and Tashjian AH | Short chain fatty acids increase prolactin and growth hormone production and alter cell morphology in the GH3 strain of rat pituitary cells. | 1981 | Endocrinology | pmid:7238401 |
| Sigel H | The coordinating properties of d-biotin. | 1981 | Experientia | pmid:7286129 |
| Oriowo MA et al. | A comparison of the pharmacokinetic properties of three estradiol esters. | 1980 | Contraception | pmid:7389356 |
| Punnonen R et al. | Demonstration of estrogen receptors in the skin. | 1980 Jul-Sep | J. Endocrinol. Invest. | pmid:7430556 |
| Brady GP and Sharp KA | Decomposition of interaction free energies in proteins and other complex systems. | 1995 | J. Mol. Biol. | pmid:7473761 |
| Kössler F | [Effect of omega-H-perfluorinated carbonic acids on the wet weight, membrane potential and contractility of isolated skeletal muscle]. | 1978 | Acta Biol. Med. Ger. | pmid:749460 |
| Kingston EE and Duffield AM | Plasma amino acid quantitation using gas chromatography chemical ionization mass spectrometry and 13C amino acids as internal standards. | 1978 | Biomed. Mass Spectrom. | pmid:749957 |
| Xu RX et al. | NMR determination of the structures of peroxycobalt(III) bleomycin and cobalt(III) bleomycin, products of the aerobic oxidation of cobalt(II) bleomycin by dioxygen. | 1994 | Biochemistry | pmid:7508261 |
| Liakopoulou E et al. | Stimulation of fetal hemoglobin production by short chain fatty acids. | 1995 | Blood | pmid:7579419 |
| Tune BM and Hsu CY | Effects of nephrotoxic beta-lactam antibiotics on the mitochondrial metabolism of monocarboxylic substrates. | 1995 | J. Pharmacol. Exp. Ther. | pmid:7616399 |
| Sagar PM et al. | Acute pouchitis and deficiencies of fuel. | 1995 | Dis. Colon Rectum | pmid:7736879 |
| Jackson DE and Srienc F | Novel methods to synthesize polyhydroxyalkanoates. | 1994 | Ann. N. Y. Acad. Sci. | pmid:7832504 |
| Bryant BP and Moore PA | Factors affecting the sensitivity of the lingual trigeminal nerve to acids. | 1995 | Am. J. Physiol. | pmid:7840339 |
| Ni X and Cole RD | Effects of various salts and pH on the stability of the nucleosome in chromatin fragments. | 1994 | Biochemistry | pmid:8049228 |
| Hiller EJ and Milner AD | Betamethasone 17 valerate aerosol and disodium chromoglycate in severe childhood asthma. | 1975 | Br J Dis Chest | pmid:806293 |
| Kubota K and Maibach HI | In vitro percutaneous permeation of betamethasone and betamethasone 17-valerate. | 1993 | J Pharm Sci | pmid:8254489 |
| PospÃsil S et al. | Activity of the AIB factor observed in prokaryotic and eukaryotic microorganisms. | 1993 | Folia Microbiol. (Praha) | pmid:8375780 |
| Munro DD et al. | Betamethasone valerate ointment compared with fluocinonide FAPG. | 1977 | Arch Dermatol | pmid:856049 |
| Brauchli P et al. | Electrocortical and autonomic alteration by administration of a pleasant and an unpleasant odor. | 1995 | Chem. Senses | pmid:8564425 |
| Metherate R and Ashe JH | GABAergic suppression prevents the appearance and subsequent fatigue of an NMDA receptor-mediated potential in neocortex. | 1995 | Brain Res. | pmid:8616625 |
| Hölzle E and Plewig G | Effects of dermatitis, stripping, and steroids on the morphology of corneocytes. A new bioassay. | 1977 | J. Invest. Dermatol. | pmid:864272 |
| Schaefer FW et al. | Aerobic and anaerobic fermentation of glucose by Echinostoma liei. | 1977 | J. Parasitol. | pmid:886405 |
| Siavoshian S et al. | Comparison of the effect of different short chain fatty acids on the growth and differentiation of human colonic carcinoma cell lines in vitro. | 1997 | Cell Biol. Int. | pmid:9243803 |
| de Bernard M et al. | TPA and butyrate increase cell sensitivity to the vacuolating toxin of Helicobacter pylori. | 1998 | FEBS Lett. | pmid:9781682 |