Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Uterine Hemorrhage | D014592 | 6 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| CORSE J et al. | Alpha-Amino-beta-mercapto-n-valeric acid hydrochloride. | 1948 | J. Am. Chem. Soc. | pmid:18918849 |
| Khenkin AM and Neumann R | Oxidative C-C bond cleavage of primary alcohols and vicinal diols catalyzed by H5PV2Mo10O40 by an electron transfer and oxygen transfer reaction mechanism. | 2008 | J. Am. Chem. Soc. | pmid:18841966 |
| Rishel MJ et al. | Conformationally constrained analogues of bleomycin A5. | 2003 | J. Am. Chem. Soc. | pmid:12926941 |
| Dangel BD et al. | Selective functionalization of amino acids in water: a synthetic method via catalytic C-H bond activation. | 2001 | J. Am. Chem. Soc. | pmid:11506585 |
| Nery J et al. | Influence of dietary protein content and source on colonic fermentative activity in dogs differing in body size and digestive tolerance. | 2012 | J. Anim. Sci. | pmid:22328724 |
| Barry KA et al. | Adaptation of healthy adult cats to select dietary fibers in vivo affects gas and short-chain fatty acid production from fiber fermentation in vitro. | 2011 | J. Anim. Sci. | pmid:21531846 |
| Kanakupt K et al. | Effects of short-chain fructooligosaccharides and galactooligosaccharides, individually and in combination, on nutrient digestibility, fecal fermentative metabolite concentrations, and large bowel microbial ecology of healthy adults cats. | 2011 | J. Anim. Sci. | pmid:21216981 |
| May ML et al. | Effects of dry-rolled or steam-flaked corn finishing diets with or without twenty-five percent dried distillers grains on ruminal fermentation and apparent total tract digestion. | 2009 | J. Anim. Sci. | pmid:19648506 |
| Goiri I et al. | Use of chitosans to modulate ruminal fermentation of a 50:50 forage-to-concentrate diet in sheep. | 2010 | J. Anim. Sci. | pmid:19854994 |
| Barry KA et al. | Low-level fructan supplementation of dogs enhances nutrient digestion and modifies stool metabolite concentrations, but does not alter fecal microbiota populations. | 2009 | J. Anim. Sci. | pmid:19574565 |
| Gozho GN et al. | Effects of type of canola protein supplement on ruminal fermentation and nutrient flow to the duodenum in beef heifers. | 2009 | J. Anim. Sci. | pmid:19542502 |
| Song R et al. | Effects of feeding diets containing bacitracin methylene disalicylate to heat-stressed finishing pigs. | 2011 | J. Anim. Sci. | pmid:21297060 |
| Varel VH et al. | Odorant production and persistence of Escherichia coli in manure slurries from cattle fed zero, twenty, forty, or sixty percent wet distillers grains with solubles. | 2008 | J. Anim. Sci. | pmid:18676716 |
| Robles V et al. | Effects of feeding frequency on intake, ruminal fermentation, and feeding behavior in heifers fed high-concentrate diets. | 2007 | J. Anim. Sci. | pmid:17609471 |
| Cardozo PW et al. | Effects of natural plant extracts on ruminal protein degradation and fermentation profiles in continuous culture. | 2004 | J. Anim. Sci. | pmid:15542469 |
| Manzanilla EG et al. | Effect of plant extracts and formic acid on the intestinal equilibrium of early-weaned pigs. | 2004 | J. Anim. Sci. | pmid:15542467 |
| Kristensen NB and Harmon DL | Effect of increasing ruminal butyrate absorption on splanchnic metabolism of volatile fatty acids absorbed from the washed reticulorumen of steers. | 2004 | J. Anim. Sci. | pmid:15537776 |
| Kristensen NB and Harmon DL | Splanchnic metabolism of volatile fatty acids absorbed from the washed reticulorumen of steers. | 2004 | J. Anim. Sci. | pmid:15309950 |
| Akay V et al. | NutriDense and waxy corn hybrids: effects on site and extent of disappearance of nutrients in sheep. | 2002 | J. Anim. Sci. | pmid:12019623 |
| Kristensen NB | Rumen microbial sequestration of [2-(13)C]acetate in cattle. | 2001 | J. Anim. Sci. | pmid:11583438 |