Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Uterine Hemorrhage | D014592 | 6 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kerr KR et al. | Apparent total tract energy and macronutrient digestibility and fecal fermentative end-product concentrations of domestic cats fed extruded, raw beef-based, and cooked beef-based diets. | 2012 | J. Anim. Sci. | pmid:22003235 |
| Kanakupt K et al. | Effects of short-chain fructooligosaccharides and galactooligosaccharides, individually and in combination, on nutrient digestibility, fecal fermentative metabolite concentrations, and large bowel microbial ecology of healthy adults cats. | 2011 | J. Anim. Sci. | pmid:21216981 |
| Barry KA et al. | Low-level fructan supplementation of dogs enhances nutrient digestion and modifies stool metabolite concentrations, but does not alter fecal microbiota populations. | 2009 | J. Anim. Sci. | pmid:19574565 |
| Gozho GN et al. | Effects of type of canola protein supplement on ruminal fermentation and nutrient flow to the duodenum in beef heifers. | 2009 | J. Anim. Sci. | pmid:19542502 |
| Robles V et al. | Effects of feeding frequency on intake, ruminal fermentation, and feeding behavior in heifers fed high-concentrate diets. | 2007 | J. Anim. Sci. | pmid:17609471 |
| Kristensen NB | Rumen microbial sequestration of [2-(13)C]acetate in cattle. | 2001 | J. Anim. Sci. | pmid:11583438 |
| Bandyk CA et al. | Effect of ruminal vs postruminal administration of degradable protein on utilization of low-quality forage by beef steers. | 2001 | J. Anim. Sci. | pmid:11204704 |
| Rossi S et al. | Antimicrobial efficacy of a new antibiotic-loaded poly(hydroxybutyric-co-hydroxyvaleric acid) controlled release system. | 2004 | J. Antimicrob. Chemother. | pmid:15537698 |
| Chee JY et al. | Expression of Aeromonas caviae polyhydroxyalkanoate synthase gene in Burkholderia sp. USM (JCM15050) enables the biosynthesis of SCL-MCL PHA from palm oil products. | 2012 | J. Appl. Microbiol. | pmid:22054430 |
| Park MO et al. | Production of alternatives to fuel oil from organic waste by the alkane-producing bacterium, Vibrio furnissii M1. | 2005 | J. Appl. Microbiol. | pmid:15659187 |
| Bourriaud C et al. | Lactate is mainly fermented to butyrate by human intestinal microfloras but inter-individual variation is evident. | 2005 | J. Appl. Microbiol. | pmid:15960680 |
| Ruman J et al. | Severe hypertriglyceridemia and pancreatitis following hormone replacement prior to cryothaw transfer. | 2002 | J. Assist. Reprod. Genet. | pmid:11958513 |
| SampaÃo MA and Geber S | Births after transfer of zona-free blastocysts in oocyte donation cycles. | 2001 | J. Assist. Reprod. Genet. | pmid:11411431 |
| OTTKE RC et al. | Isotopic acetate and isovalerate in the synthesis of ergosterol by Neurospora. | 1951 | J. Biol. Chem. | pmid:14832256 |
| SIEGEL I and LORBER V | Conversion of C14, C13, labeled n-valerate to rat liver glycogen. | 1951 | J. Biol. Chem. | pmid:14832274 |
| MEISTER A | Studies on d- and tau-alpha-keto-beta-methylvaleric acids. | 1951 | J. Biol. Chem. | pmid:14841174 |
| COON MJ | The metabolic fate of the isopropyl group of leucine. | 1950 | J. Biol. Chem. | pmid:14794691 |
| STADTMAN ER et al. | Tracer experiments on the mechanism of synthesis of valeric and caproic acids by Clostridium kluyveri. | 1949 | J. Biol. Chem. | pmid:18116989 |
| BUEDING E | Formation of tiglic and n-valeric acids by bacteria-free Ascaris lumbricoides. | 1953 | J. Biol. Chem. | pmid:13061475 |
| Ortiz-Caro J et al. | Modulation of thyroid hormone nuclear receptors by short-chain fatty acids in glial C6 cells. Role of histone acetylation. | 1986 | J. Biol. Chem. | pmid:3771518 |