Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Uterine Hemorrhage | D014592 | 6 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tomoda K et al. | Cigarette smoke decreases organic acids levels and population of bifidobacterium in the caecum of rats. | 2011 | J Toxicol Sci | pmid:21628954 |
| Mueller A et al. | Body composition and bone mineral density in male-to-female transsexuals during cross-sex hormone therapy using gonadotrophin-releasing hormone agonist. | 2011 | Exp. Clin. Endocrinol. Diabetes | pmid:20625973 |
| Wang HH et al. | Biosynthesis of polyhydroxyalkanoate homopolymers by Pseudomonas putida. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21046374 |
| Albuquerque MG et al. | Mixed culture polyhydroxyalkanoate (PHA) production from volatile fatty acid (VFA)-rich streams: effect of substrate composition and feeding regime on PHA productivity, composition and properties. | 2011 | J. Biotechnol. | pmid:21034785 |
| Schmidt J et al. | Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3. | 2011 | J. Biol. Chem. | pmid:21220428 |
| Gross NB et al. | Cortical ionotropic glutamate receptor antagonism protects against methamphetamine-induced striatal neurotoxicity. | 2011 | Neuroscience | pmid:21946008 |
| Xiccato G et al. | Effect of decreasing dietary protein level and replacing starch with soluble fibre on digestive physiology and performance of growing rabbits. | 2011 | Animal | pmid:22440170 |
| Baena S et al. | Desulfosoma caldarium gen. nov., sp. nov., a thermophilic sulfate-reducing bacterium from a terrestrial hot spring. | 2011 | Int. J. Syst. Evol. Microbiol. | pmid:20418410 |
| Choi KH et al. | Efficiency of laser-assisted intracytoplasmic sperm injection in a human assisted reproductive techniques program. | 2011 | Clin Exp Reprod Med | pmid:22384434 |
| Kamath MS et al. | Blastocyst cryopreservation using solid surface vitrification: A preliminary study. | 2011 | J Hum Reprod Sci | pmid:22346077 |
| Cleland TA et al. | Sequential mechanisms underlying concentration invariance in biological olfaction. | 2011 | Front Neuroeng | pmid:22287949 |
| Zhang J et al. | Synthesis and insecticidal activities of new ester-derivatives of Celangulin-V. | 2011 | Int J Mol Sci | pmid:22272151 |
| Goh J et al. | The PEX7-mediated peroxisomal import system is required for fungal development and pathogenicity in Magnaporthe oryzae. | 2011 | PLoS ONE | pmid:22194815 |
| Weickert MO et al. | Changes in dominant groups of the gut microbiota do not explain cereal-fiber induced improvement of whole-body insulin sensitivity. | 2011 | Nutr Metab (Lond) | pmid:22177085 |
| Lei HT et al. | Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni. | 2011 | Protein Sci. | pmid:21328631 |
| Kumar A et al. | Redox homeostasis in mycobacteria: the key to tuberculosis control? | 2011 | Expert Rev Mol Med | pmid:22172201 |
| Kuldeep C et al. | Randomized comparison of topical betamethasone valerate foam, intralesional triamcinolone acetonide and tacrolimus ointment in management of localized alopecia areata. | 2011 | Int J Trichology | pmid:21769231 |
| Glogauer A et al. | Identification and characterization of a new true lipase isolated through metagenomic approach. | 2011 | Microb. Cell Fact. | pmid:21762508 |
| Wijekoon KC et al. | Effect of organic loading rate on VFA production, organic matter removal and microbial activity of a two-stage thermophilic anaerobic membrane bioreactor. | 2011 | Bioresour. Technol. | pmid:21256737 |
| Jawara M et al. | Field testing of different chemical combinations as odour baits for trapping wild mosquitoes in The Gambia. | 2011 | PLoS ONE | pmid:21637337 |
| Barry KA et al. | Adaptation of healthy adult cats to select dietary fibers in vivo affects gas and short-chain fatty acid production from fiber fermentation in vitro. | 2011 | J. Anim. Sci. | pmid:21531846 |
| Dixon E et al. | Solid-phase microextraction and the human fecal VOC metabolome. | 2011 | PLoS ONE | pmid:21494609 |
| Pagani I et al. | Complete genome sequence of Desulfobulbus propionicus type strain (1pr3). | 2011 | Stand Genomic Sci | pmid:21475592 |
| AbuGhazaleh AA et al. | The effect of replacing corn with glycerol on ruminal bacteria in continuous culture fermenters. | 2011 | J Anim Physiol Anim Nutr (Berl) | pmid:20880288 |
| Chen XX et al. | Synthetic studies on (+)-biotin, part 15: A chiral squaramide-mediated enantioselective alcoholysis approach toward the total synthesis of (+)-biotin. | 2011 | Chem. Pharm. Bull. | pmid:21467680 |
| Adams JB et al. | Gastrointestinal flora and gastrointestinal status in children with autism--comparisons to typical children and correlation with autism severity. | 2011 | BMC Gastroenterol | pmid:21410934 |
| Kinross JM et al. | Gut microbiome-host interactions in health and disease. | 2011 | Genome Med | pmid:21392406 |
| Neidig N et al. | Secondary metabolites of Pseudomonas fluorescens CHA0 drive complex non-trophic interactions with bacterivorous nematodes. | 2011 | Microb. Ecol. | pmid:21360140 |
| Huang R et al. | Control of postharvest Botrytis fruit rot of strawberry by volatile organic compounds of Candida intermedia. | 2011 | Phytopathology | pmid:21323467 |
| Kanakupt K et al. | Effects of short-chain fructooligosaccharides and galactooligosaccharides, individually and in combination, on nutrient digestibility, fecal fermentative metabolite concentrations, and large bowel microbial ecology of healthy adults cats. | 2011 | J. Anim. Sci. | pmid:21216981 |
| Jensen JT et al. | Effective treatment of heavy menstrual bleeding with estradiol valerate and dienogest: a randomized controlled trial. | 2011 | Obstet Gynecol | pmid:21422847 |
| Song R et al. | Effects of feeding diets containing bacitracin methylene disalicylate to heat-stressed finishing pigs. | 2011 | J. Anim. Sci. | pmid:21297060 |
| Theil PK et al. | Products deriving from microbial fermentation are linked to insulinaemic response in pigs fed breads prepared from whole-wheat grain and wheat and rye ingredients. | 2011 | Br. J. Nutr. | pmid:20923581 |
| Aklujkar M et al. | The genome of Geobacter bemidjiensis, exemplar for the subsurface clade of Geobacter species that predominate in Fe(III)-reducing subsurface environments. | 2010 | BMC Genomics | pmid:20828392 |
| Sentürk E et al. | Treatment efficiency and VFA composition of a thermophilic anaerobic contact reactor treating food industry wastewater. | 2010 | J. Hazard. Mater. | pmid:20022175 |
| Cañadillas-Delgado L et al. | Intramolecular ferro- and antiferromagnetic interactions in oxo-carboxylate bridged digadolinium(III) complexes. | 2010 | Dalton Trans | pmid:20593071 |
| Bozell JJ | Chemistry. Connecting biomass and petroleum processing with a chemical bridge. | 2010 | Science | pmid:20671177 |
| Saunders MJ et al. | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. | 2010 | Curr Protoc Cytom | pmid:20938917 |
| Sarlea M et al. | Valeronitrile hydrolysis in supercritical water. | 2010 | ChemSusChem | pmid:19924764 |
| Palkovits R | Pentenoic acid pathways for cellulosic biofuels. | 2010 | Angew. Chem. Int. Ed. Engl. | pmid:20480484 |
| Lange JP et al. | Valeric biofuels: a platform of cellulosic transportation fuels. | 2010 | Angew. Chem. Int. Ed. Engl. | pmid:20446282 |
| Merrouche R et al. | Dithiolopyrrolone antibiotic formation induced by adding valeric acid to the culture broth of Saccharothrix algeriensis. | 2010 | J. Nat. Prod. | pmid:20507156 |
| Saunders MJ et al. | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. | 2010 | Assay Drug Dev Technol | pmid:20035615 |
| Ekins S et al. | A predictive ligand-based Bayesian model for human drug-induced liver injury. | 2010 | Drug Metab. Dispos. | pmid:20843939 |
| Elgindy EA et al. | Does luteal estradiol supplementation have a role in long agonist cycles? | 2010 | Fertil. Steril. | pmid:19243745 |
| Höfer P et al. | Production of functionalized polyhydroxyalkanoates by genetically modified Methylobacterium extorquens strains. | 2010 | Microb. Cell Fact. | pmid:20846434 |
| Connor SC et al. | Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes. | 2010 | Mol Biosyst | pmid:20567778 |
| Valerio F et al. | Effects of probiotic Lactobacillus paracasei-enriched artichokes on constipated patients: a pilot study. | 2010 | J. Clin. Gastroenterol. | pmid:20495470 |
| MartÃnez ME et al. | Comparison of fermentation of diets of variable composition and microbial populations in the rumen of sheep and Rusitec fermenters. I. Digestibility, fermentation parameters, and microbial growth. | 2010 | J. Dairy Sci. | pmid:20655438 |
| Sun H et al. | Complete genome sequence of Desulfarculus baarsii type strain (2st14). | 2010 | Stand Genomic Sci | pmid:21304732 |
| Neirinck B et al. | Influence of short chain organic acids and bases on the wetting properties and surface energy of submicrometer ceramic powders. | 2010 | J Colloid Interface Sci | pmid:20553808 |
| Li J et al. | Rate enhancement of an interfacial biochemical reaction through localization of substrate and enzyme by an adaptor domain. | 2010 | J Phys Chem B | pmid:21047083 |
| El Amine Dib M et al. | Characterization of volatile compounds of Daucus crinitus Desf. Headspace Solid Phase Microextraction as alternative technique to Hydrodistillation. | 2010 | Chem Cent J | pmid:20858266 |
| Oliveira JB et al. | Administration of single-dose GnRH agonist in the luteal phase in ICSI cycles: a meta-analysis. | 2010 | Reprod. Biol. Endocrinol. | pmid:20825643 |
| Roze LV et al. | Volatile profiling reveals intracellular metabolic changes in Aspergillus parasiticus: veA regulates branched chain amino acid and ethanol metabolism. | 2010 | BMC Biochem. | pmid:20735852 |
| Andriamihaja M et al. | Colon luminal content and epithelial cell morphology are markedly modified in rats fed with a high-protein diet. | 2010 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:20689060 |
| Ricco R and Kanduc D | Hepatitis B virus and Homo sapiens proteome-wide analysis: A profusion of viral peptide overlaps in neuron-specific human proteins. | 2010 | Biologics | pmid:20531967 |
| Barry KA et al. | Dietary cellulose, fructooligosaccharides, and pectin modify fecal protein catabolites and microbial populations in adult cats. | 2010 | J. Anim. Sci. | pmid:20495116 |
| Potts BC and Lam KS | Generating a generation of proteasome inhibitors: from microbial fermentation to total synthesis of salinosporamide a (marizomib) and other salinosporamides. | 2010 | Mar Drugs | pmid:20479958 |
| Basant A et al. | Alterations in urine, serum and brain metabolomic profiles exhibit sexual dimorphism during malaria disease progression. | 2010 | Malar. J. | pmid:20412601 |
| Eggink M et al. | Targeted LC-MS derivatization for aldehydes and carboxylic acids with a new derivatization agent 4-APEBA. | 2010 | Anal Bioanal Chem | pmid:20238107 |
| Okumu FO et al. | Development and field evaluation of a synthetic mosquito lure that is more attractive than humans. | 2010 | PLoS ONE | pmid:20126628 |
| Olanga EA et al. | Attraction of Anopheles gambiae to odour baits augmented with heat and moisture. | 2010 | Malar. J. | pmid:20051143 |
| Sato H and Shiogama Y | Acetone and isopropanol in ruminal fluid and feces of lactating dairy cows. | 2010 | J. Vet. Med. Sci. | pmid:19959888 |
| Thrash JC et al. | Description of the novel perchlorate-reducing bacteria Dechlorobacter hydrogenophilus gen. nov., sp. nov.and Propionivibrio militaris, sp. nov. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19921177 |
| Bengtsson S et al. | Production of polyhydroxyalkanoates from fermented sugar cane molasses by a mixed culture enriched in glycogen accumulating organisms. | 2010 | J. Biotechnol. | pmid:19958801 |
| Sorokin DY et al. | Propionate and butyrate dependent bacterial sulfate reduction at extremely haloalkaline conditions and description of Desulfobotulus alkaliphilus sp. nov. | 2010 | Extremophiles | pmid:19888546 |
| Goiri I et al. | Use of chitosans to modulate ruminal fermentation of a 50:50 forage-to-concentrate diet in sheep. | 2010 | J. Anim. Sci. | pmid:19854994 |
| Binsl TW et al. | Measuring non-steady-state metabolic fluxes in starch-converting faecal microbiota in vitro. | 2010 | Benef Microbes | pmid:21831778 |
| Morales-Ledesma L et al. | Unilateral sectioning of the superior ovarian nerve of rats with polycystic ovarian syndrome restores ovulation in the innervated ovary. | 2010 | Reprod. Biol. Endocrinol. | pmid:20723258 |
| Dafopoulos K et al. | The effect of estrogens on plasma ghrelin concentrations in women. | 2010 | J. Endocrinol. Invest. | pmid:20348837 |
| Suzuki D et al. | Desulfovibrio butyratiphilus sp. nov., a Gram-negative, butyrate-oxidizing, sulfate-reducing bacterium isolated from an anaerobic municipal sewage sludge digester. | 2010 | Int. J. Syst. Evol. Microbiol. | pmid:19654341 |
| Hall MB et al. | Carbohydrate source and protein degradability alter lactation, ruminal, and blood measures. | 2010 | J. Dairy Sci. | pmid:20059929 |
| Cannon SJ et al. | Inclusion of psyllium in milk replacer for neonatal calves. 2. Effects on volatile fatty acid concentrations, microbial populations, and gastrointestinal tract size. | 2010 | J. Dairy Sci. | pmid:20855009 |
| MartÃnez Casado FJ et al. | Thermal and structural study of the crystal phases and mesophases in the lithium and thallium(i) propanoates and pentanoates binary systems: formation of mixed salts and stabilization of the ionic liquid crystal phase. | 2010 | J Phys Chem B | pmid:20684631 |
| Chung YH et al. | Ruminal and blood responses to propylene glycol during frequent feeding. | 2009 | J. Dairy Sci. | pmid:19700718 |
| Burden DK et al. | HCl uptake through films of pentanoic acid and pentanoic acid/hexanol mixtures at the surface of sulfuric acid. | 2009 | J Phys Chem A | pmid:19924886 |
| Karnati SK et al. | Investigating unsaturated fat, monensin, or bromoethanesulfonate in continuous cultures retaining ruminal protozoa. I. Fermentation, biohydrogenation, and microbial protein synthesis. | 2009 | J. Dairy Sci. | pmid:19620669 |
| Ghanem ME et al. | The effect of luteal phase support protocol on cycle outcome and luteal phase hormone profile in long agonist protocol intracytoplasmic sperm injection cycles: a randomized clinical trial. | 2009 | Fertil. Steril. | pmid:19464001 |
| Penner GB et al. | Effect of dietary forage to concentrate ratio on volatile fatty acid absorption and the expression of genes related to volatile fatty acid absorption and metabolism in ruminal tissue. | 2009 | J. Dairy Sci. | pmid:19448011 |
| Biswas A et al. | Production of poly-3-hydroxyalkanoic acids by a moderately halophilic bacterium, Halomonas marina HMA 103 isolated from solar saltern of Orissa, India. | 2009 | Acta Microbiol Immunol Hung | pmid:19621765 |
| MartÃnez Casado FJ et al. | Structural and thermodynamic study on short metal alkanoates: lithium propanoate and pentanoate. | 2009 | J Phys Chem B | pmid:19736960 |
| MartÃnez ME et al. | Effects of dilution rate and retention time of concentrate on efficiency of microbial growth, methane production, and ruminal fermentation in Rusitec fermenters. | 2009 | J. Dairy Sci. | pmid:19620676 |
| Zhang P et al. | Waste activated sludge hydrolysis and short-chain fatty acids accumulation under mesophilic and thermophilic conditions: effect of pH. | 2009 | Water Res. | pmid:19555988 |
| Zhang HF et al. | Biosynthesis and characterization of 3-hydroxyalkanoate terpolyesters with adjustable properties by Aeromonas hydrophila. | 2009 | Biotechnol. Bioeng. | pmid:19517520 |
| Aklujkar M et al. | The genome sequence of Geobacter metallireducens: features of metabolism, physiology and regulation common and dissimilar to Geobacter sulfurreducens. | 2009 | BMC Microbiol. | pmid:19473543 |
| Tellam RL et al. | Unlocking the bovine genome. | 2009 | BMC Genomics | pmid:19393070 |
| Ishihara K et al. | Identification of urinary biomarkers useful for distinguishing a difference in mechanism of toxicity in rat model of cholestasis. | 2009 | Basic Clin. Pharmacol. Toxicol. | pmid:19486331 |
| German DP | Do herbivorous minnows have "plug-flow reactor" guts? Evidence from digestive enzyme activities, gastrointestinal fermentation, and luminal nutrient concentrations. | 2009 | J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. | pmid:19363616 |
| Zanor MI et al. | Metabolic characterization of loci affecting sensory attributes in tomato allows an assessment of the influence of the levels of primary metabolites and volatile organic contents. | 2009 | J. Exp. Bot. | pmid:19346240 |
| Spring S et al. | The photosynthetic apparatus and its regulation in the aerobic gammaproteobacterium Congregibacter litoralis gen. nov., sp. nov. | 2009 | PLoS ONE | pmid:19287491 |
| Xi Y et al. | Analysis on relationship between extreme pathways and correlated reaction sets. | 2009 | BMC Bioinformatics | pmid:19208161 |
| Dinalo JE and Relman DA | Cross-talk in the gut. | 2009 | Genome Biol. | pmid:19216729 |
| Ducros M et al. | Spectral unmixing: analysis of performance in the olfactory bulb in vivo. | 2009 | PLoS ONE | pmid:19198655 |
| Kim SH et al. | HemoHIM improves ovarian morphology and decreases expression of nerve growth factor in rats with steroid-induced polycystic ovaries. | 2009 | J Med Food | pmid:20041792 |
| Sato H | Increased fecal lactate and decreased volatile fatty acid (VFA), particularly n-butyrate concentrations in diarrheic young calves. | 2009 | J. Vet. Med. Sci. | pmid:19194088 |
| Yamin BM and Othman EA | 3-Methyl-2-propionamido-butanoic acid. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21582407 |
| Thenmozhi M et al. | tert-Butyl 3-[2,2-bis-(ethoxy-carbon-yl)vin-yl]-2-bromo-methyl-1H-indole-1-carboxyl-ate. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21578388 |
| Newland JG and Abdel-Rahman SM | Update on terbinafine with a focus on dermatophytoses. | 2009 | Clin Cosmet Investig Dermatol | pmid:21436968 |
| Akdeniz N et al. | Air sampling and analysis method for volatile organic compounds (VOCs) related to field-scale mortality composting operations. | 2009 | J. Agric. Food Chem. | pmid:19514732 |