Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Uterine Hemorrhage | D014592 | 6 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Saghyan AA et al. | The effects of short-chain fatty acids on the neuronal membrane functions of Helix pomatia. III. 22Na efflux from the cells. | 1986 | Cell. Mol. Neurobiol. | pmid:3829102 |
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| Kasukabe T et al. | Effects of combined treatment with rapamycin and cotylenin A, a novel differentiation-inducing agent, on human breast carcinoma MCF-7 cells and xenografts. | 2005 | Breast Cancer Res. | pmid:16457690 |
| Suzuki-Mizushima Y et al. | Enhancement of NGF- and cholera toxin-induced neurite outgrowth by butyrate in PC12 cells. | 2002 | Brain Res. | pmid:12270499 |
| Simons CT et al. | Mecamylamine reduces nicotine cross-desensitization of trigeminal caudalis neuronal responses to oral chemical irritation. | 2003 | Brain Res. | pmid:14575899 |
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| Stone TW | Excitant activity of methyl derivatives of quinolinic acid on rat cortical neurones. | 1984 | Br. J. Pharmacol. | pmid:6546701 |
| Huuskonen J et al. | Regulation of microglial inflammatory response by sodium butyrate and short-chain fatty acids. | 2004 | Br. J. Pharmacol. | pmid:14744800 |
| Caminero A et al. | Differences in gluten metabolism among healthy volunteers, coeliac disease patients and first-degree relatives. | 2015 | Br. J. Nutr. | pmid:26428276 |
| Theil PK et al. | Products deriving from microbial fermentation are linked to insulinaemic response in pigs fed breads prepared from whole-wheat grain and wheat and rye ingredients. | 2011 | Br. J. Nutr. | pmid:20923581 |
| Weber G | Letter: The treatment of cavernous haemangioma with topical betamethasone 17 valerate. | 1973 | Br. J. Dermatol. | pmid:4802519 |
| Propper DJ et al. | Phase II study of the oxygen saturation curve left shifting agent BW12C in combination with the hypoxia activated drug mitomycin C in advanced colorectal cancer. | 2000 | Br. J. Cancer | pmid:10839290 |
| Cameron IT et al. | Oocyte donation: a review. | 1989 | Br J Obstet Gynaecol | pmid:2673336 |