Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Uterine Hemorrhage | D014592 | 6 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Carlier J et al. | Quantification of [1-(5-fluoropentyl)-1H-indol-3-yl](naphthalene-1-yl)methanone (AM-2201) and 13 metabolites in human and rat plasma by liquid chromatography-tandem mass spectrometry. | 2016 | J Chromatogr A | pmid:27208987 |
| Liu G et al. | Enoyl-CoA hydratase mediates polyhydroxyalkanoate mobilization in Haloferax mediterranei. | 2016 | Sci Rep | pmid:27052994 |
| Cal AJ et al. | Methanotrophic production of polyhydroxybutyrate-co-hydroxyvalerate with high hydroxyvalerate content. | 2016 | Int. J. Biol. Macromol. | pmid:26920242 |
| Moen B et al. | Extrusion of barley and oat influence the fecal microbiota and SCFA profile of growing pigs. | 2016 | Food Funct | pmid:26758043 |
| Cameron IT et al. | Oocyte donation: a review. | 1989 | Br J Obstet Gynaecol | pmid:2673336 |
| Osterloh J et al. | Biochemical relationships between Reye's and Reye's-like metabolic and toxicological syndromes. | 1989 Jul-Aug | Med Toxicol Adverse Drug Exp | pmid:2671597 |
| Tomiyama T et al. | Synthesis and biological activity of novel carbacyclins having bicyclic substituents on the omega-chain. | 1989 | J. Med. Chem. | pmid:2666669 |
| Park JH et al. | Valeric acid induces cell cycle arrest at G1 phase in CHO cell cultures and improves recombinant antibody productivity. | 2016 | Biotechnol J | pmid:26663903 |
| Stang C and Harnisch F | The Dilemma of Supporting Electrolytes for Electroorganic Synthesis: A Case Study on Kolbe Electrolysis. | 2016 | ChemSusChem | pmid:26609800 |
| Caminero A et al. | Differences in gluten metabolism among healthy volunteers, coeliac disease patients and first-degree relatives. | 2015 | Br. J. Nutr. | pmid:26428276 |
| Park SO and Park BS | Bifidogenic effect of grain larvae extract on serum lipid, glucose and intestinal microflora in rats. | 2015 | J. Biosci. | pmid:26333397 |
| Siddiqui O et al. | Percutaneous absorption of steroids: relative contributions of epidermal penetration and dermal clearance. | 1989 | J Pharmacokinet Biopharm | pmid:2614679 |
| Park M et al. | Determination of XLR-11 and its metabolites in hair by liquid chromatography-tandem mass spectrometry. | 2015 | J Pharm Biomed Anal | pmid:26070160 |
| Sakamoto O et al. | Phenotypic Variability and Newly Identified Mutations of the IVD Gene in Japanese Patients with Isovaleric Acidemia. | 2015 | Tohoku J. Exp. Med. | pmid:26018748 |
| Kone P et al. | Effect of the combination of monensin and isoacids on rumen fermentation in vitro. | 1989 | J. Dairy Sci. | pmid:2600235 |
| Liang S and Wan C | Carboxylic acid production from brewer's spent grain via mixed culture fermentation. | 2015 | Bioresour. Technol. | pmid:25698409 |
| Erol Öztürk Y et al. | Validation of JWH-018 and its metabolites in blood and urine by UPLC-MS/MS: Monitoring in forensic cases. | 2015 | Forensic Sci. Int. | pmid:25616218 |
| De Clerck F et al. | R 68 070: thromboxane A2 synthetase inhibition and thromboxane A2/prostaglandin endoperoxide receptor blockade combined in one molecule--I. Biochemical profile in vitro. | 1989 | Thromb. Haemost. | pmid:2546278 |
| De Clerck F et al. | R 68 070: thromboxane A2 synthetase inhibition and thromboxane A2/prostaglandin endoperoxide receptor blockade combined in one molecule--II. Pharmacological effects in vivo and ex vivo. | 1989 | Thromb. Haemost. | pmid:2526385 |
| Verhoeven E et al. | Pink urine. | 2014 | Clin Toxicol (Phila) | pmid:25233954 |