Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Uterine Hemorrhage | D014592 | 6 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hu ZH et al. | Application of response surface methodology for optimization of acidogenesis of cattail by rumen cultures. | 2006 | Bioresour. Technol. | pmid:16289873 |
| Špoljarić IV et al. | Mathematical modeling of poly[(R)-3-hydroxyalkanoate] synthesis by Cupriavidus necator DSM 545 on substrates stemming from biodiesel production. | 2013 | Bioresour. Technol. | pmid:23454805 |
| Zhao QB and Yu HQ | Fermentative H2 production in an upflow anaerobic sludge blanket reactor at various pH values. | 2008 | Bioresour. Technol. | pmid:17482810 |
| Nie Y et al. | Acetate yield increased by gas circulation and fed-batch fermentation in a novel syntrophic acetogenesis and homoacetogenesis coupling system. | 2008 | Bioresour. Technol. | pmid:17681788 |
| Kihara T et al. | Bacillus cereus-type polyhydroxyalkanoate biosynthetic gene cluster contains R-specific enoyl-CoA hydratase gene. | 2017 | Biosci. Biotechnol. Biochem. | pmid:28532241 |
| Kim JD and Kang KH | Isolation of Lactobacillus sakei strain KJ-2008 and its removal of characteristic malodorous gases under anaerobic culture conditions. | 2004 | Biosci. Biotechnol. Biochem. | pmid:15618611 |
| de Barros DP et al. | Synthesis of alkyl esters by cutinase in miniemulsion and organic solvent media. | 2009 | Biotechnol J | pmid:19418474 |
| Park JH et al. | Valeric acid induces cell cycle arrest at G1 phase in CHO cell cultures and improves recombinant antibody productivity. | 2016 | Biotechnol J | pmid:26663903 |
| Wong MS et al. | Engineering poly(3-hydroxybutyrate-co-3-hydroxyvalerate) copolymer composition in E. coli. | 2008 | Biotechnol. Bioeng. | pmid:17787008 |
| Yu HQ et al. | Thermodynamic analysis of product formation in mesophilic acidogenesis of lactose. | 2004 | Biotechnol. Bioeng. | pmid:15334408 |
| Batstone DJ et al. | Kinetics of thermophilic, anaerobic oxidation of straight and branched chain butyrate and valerate. | 2003 | Biotechnol. Bioeng. | pmid:12966576 |
| Pind PF et al. | Dynamics of the anaerobic process: effects of volatile fatty acids. | 2003 | Biotechnol. Bioeng. | pmid:12701145 |
| Cheong DY et al. | Production of bio-hydrogen by mesophilic anaerobic fermentation in an acid-phase sequencing batch reactor. | 2007 | Biotechnol. Bioeng. | pmid:17013946 |
| Zhang HF et al. | Biosynthesis and characterization of 3-hydroxyalkanoate terpolyesters with adjustable properties by Aeromonas hydrophila. | 2009 | Biotechnol. Bioeng. | pmid:19517520 |
| Dionisi D et al. | Biodegradable polymers from organic acids by using activated sludge enriched by aerobic periodic feeding. | 2004 | Biotechnol. Bioeng. | pmid:14966798 |
| Choi GG et al. | Production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) with high molar fractions of 3-hydroxyvalerate by a threonine-overproducing mutant of Alcaligenes sp. SH-69. | 2003 | Biotechnol. Lett. | pmid:12882163 |
| Lakshman K and Shamala TR | Enhanced biosynthesis of polyhydroxyalkanoates in a mutant strain of Rhizobium meliloti. | 2003 | Biotechnol. Lett. | pmid:12882285 |
| Soto-Cruz O et al. | Modeling of growth, lactate consumption, and volatile fatty acid production by Megasphaera elsdenii cultivated in minimal and complex media. | Biotechnol. Prog. | pmid:11934285 | |
| Shang L et al. | Sequential feeding of glucose and valerate in a fed-batch culture of Ralstonia eutropha for production of poly(hydroxybutyrate-co-hydroxyvalerate) with high 3-hydroxyvalerate fraction. | 2004 Jan-Feb | Biotechnol. Prog. | pmid:14763836 |
| Liakopoulou E et al. | Stimulation of fetal hemoglobin production by short chain fatty acids. | 1995 | Blood | pmid:7579419 |