Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Uterine Hemorrhage | D014592 | 6 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Khang G et al. | Preparation and characterization of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) microspheres for the sustained release of 5-fluorouracil. | 2001 | Biomed Mater Eng | pmid:11352116 |
| Hübener F and Laska M | A two-choice discrimination method to assess olfactory performance in pigtailed macaques, Macaca nemestrina. | 2001 | Physiol. Behav. | pmid:11282134 |
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| Snyder SE et al. | Radiolabeled cholinesterase substrates: in vitro methods for determining structure-activity relationships and identification of a positron emission tomography radiopharmaceutical for in vivo measurement of butyrylcholinesterase activity. | 2001 | J. Cereb. Blood Flow Metab. | pmid:11176278 |
| Besong S et al. | Influence of supplemental chromium on concentrations of liver triglyceride, blood metabolites and rumen VFA profile in steers fed a moderately high fat diet. | 2001 | J. Dairy Sci. | pmid:11467818 |
| Trotsenko IuA and Belova LL | [Organization and regulation of polyhydroxybutyrate/valerate biosynthesis in bacteria]. | 2000 Nov-Dec | Mikrobiologiia | pmid:11195572 |
| Diwan AD et al. | Nitric oxide modulates fracture healing. | 2000 | J. Bone Miner. Res. | pmid:10703937 |
| Paassilta M et al. | Insulin-like growth factor binding protein-1 (IGFBP-1) and IGF-I during oral and transdermal estrogen replacement therapy: relation to lipoprotein(a) levels. | 2000 | Atherosclerosis | pmid:10704627 |
| Gadda G and Fitzpatrick PF | Mechanism of nitroalkane oxidase: 2. pH and kinetic isotope effects. | 2000 | Biochemistry | pmid:10684621 |
| Wächtershäuser A et al. | PPAR-gamma is selectively upregulated in Caco-2 cells by butyrate. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10833422 |
| Palmeira CM et al. | Induction of the mitochondrial permeability transition in vitro by short-chain carboxylic acids. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10833431 |
| Gadda G et al. | Identification of an essential tyrosine residue in nitroalkane oxidase by modification with tetranitromethane. | 2000 | Biochemistry | pmid:10653664 |
| Range SP et al. | Selectivity of cyclo-oxygenase inhibitors in human pulmonary epithelial and smooth muscle cells. | 2000 | Eur. Respir. J. | pmid:10780769 |
| Dessirier JM et al. | Sensitization, desensitization and stimulus-induced recovery of trigeminal neuronal responses to oral capsaicin and nicotine. | 2000 | J. Neurophysiol. | pmid:11024077 |
| Johnson BA and Leon M | Modular representations of odorants in the glomerular layer of the rat olfactory bulb and the effects of stimulus concentration. | 2000 | J. Comp. Neurol. | pmid:10861522 |
| Propper DJ et al. | Phase II study of the oxygen saturation curve left shifting agent BW12C in combination with the hypoxia activated drug mitomycin C in advanced colorectal cancer. | 2000 | Br. J. Cancer | pmid:10839290 |
| Yang JH et al. | Hormone replacement therapy reverses the decrease in natural killer cytotoxicity but does not reverse the decreases in the T-cell subpopulation or interferon-gamma production in postmenopausal women. | 2000 | Fertil. Steril. | pmid:10927042 |
| Gadda G et al. | Identification of a cysteine residue in the active site of nitroalkane oxidase by modification with N-ethylmaleimide. | 2000 | J. Biol. Chem. | pmid:10913134 |