Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Uterine Hemorrhage | D014592 | 6 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Merrouche R et al. | Dithiolopyrrolone antibiotic formation induced by adding valeric acid to the culture broth of Saccharothrix algeriensis. | 2010 | J. Nat. Prod. | pmid:20507156 |
| Crublet ML et al. | Acylated triterpenoid saponins from the stem bark of Foetidia africana. | 2002 | J. Nat. Prod. | pmid:12444677 |
| Mahran A et al. | Mortality of Pratylenchus penetrans by Volatile Fatty Acids from Liquid Hog Manure. | 2008 | J. Nematol. | pmid:19259528 |
| Manni L et al. | Effect of exercise on ovarian morphology and expression of nerve growth factor and alpha(1)- and beta(2)-adrenergic receptors in rats with steroid-induced polycystic ovaries. | 2005 | J. Neuroendocrinol. | pmid:16280032 |
| Lapid H et al. | Odorant concentration dependence in electroolfactograms recorded from the human olfactory epithelium. | 2009 | J. Neurophysiol. | pmid:19657081 |
| Dessirier JM et al. | Sensitization, desensitization and stimulus-induced recovery of trigeminal neuronal responses to oral capsaicin and nicotine. | 2000 | J. Neurophysiol. | pmid:11024077 |
| Brasili E et al. | Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12 induce different age-related metabolic profiles revealed by 1H-NMR spectroscopy in urine and feces of mice. | 2013 | J. Nutr. | pmid:23946343 |
| Laerke HN and Jensen BB | D-tagatose has low small intestinal digestibility but high large intestinal fermentability in pigs. | 1999 | J. Nutr. | pmid:10222392 |
| Tsukahara T et al. | Stimulation of butyrate production in the large intestine of weaning piglets by dietary fructooligosaccharides and its influence on the histological variables of the large intestinal mucosa. | 2003 | J. Nutr. Sci. Vitaminol. | pmid:14974732 |
| Kobayashi D and Sakata T | Influence of temperature on short-chain fatty acid production by pig cecal bacteria in vitro. | 2006 | J. Nutr. Sci. Vitaminol. | pmid:16637232 |
| Seki M et al. | A novel synthesis of (+)-biotin from L-cysteine. | 2002 | J. Org. Chem. | pmid:12153250 |
| Schaefer FW et al. | Aerobic and anaerobic fermentation of glucose by Echinostoma liei. | 1977 | J. Parasitol. | pmid:886405 |
| Baisden LA et al. | Comparison of pepsin and alkali digestion methods for determining n-valeric acid in trichinous swine muscle. | 1972 | J. Parasitol. | pmid:4562322 |
| Vuotto ML et al. | Improvement of (+)-catechin inhibitory activity on human PMN respiratory burst by (+)-3-O-propionyl and (-)-3-O-valeryl substitution. | 2003 | J. Pharm. Pharmacol. | pmid:12724048 |
| Taniguchi K et al. | Efficacy of a liposome preparation of anti-inflammatory steroid as an ocular drug-delivery system. | 1988 | J. Pharmacobio-dyn. | pmid:3385602 |
| Taniguchi K et al. | Effects of Tween 80 and liposomes on the corneal permeability of anti-inflammatory steroids. | 1988 | J. Pharmacobio-dyn. | pmid:3221301 |
| Tune BM and Hsu CY | Effects of nephrotoxic beta-lactam antibiotics on the mitochondrial metabolism of monocarboxylic substrates. | 1995 | J. Pharmacol. Exp. Ther. | pmid:7616399 |
| Nakazawa A et al. | Evaluation of Adsorption Characteristics of a Fibrous Adsorbent Containing Zwitter-Ionic Functional Group, Targeting Organic Acids. | 2017 | J. UOEH | pmid:28331124 |
| Sato H and Shiogama Y | Acetone and isopropanol in ruminal fluid and feces of lactating dairy cows. | 2010 | J. Vet. Med. Sci. | pmid:19959888 |
| Sato H | Increased fecal lactate and decreased volatile fatty acid (VFA), particularly n-butyrate concentrations in diarrheic young calves. | 2009 | J. Vet. Med. Sci. | pmid:19194088 |