Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Uterine Hemorrhage | D014592 | 6 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Soder KJ et al. | Effect of incremental flaxseed supplementation of an herbage diet on methane output and ruminal fermentation in continuous culture. | 2012 | J. Dairy Sci. | pmid:22720950 |
| Ishizawa H et al. | Effects of betamethasone 17 valerate on the cyclic AMP system of the pig skin epidermis. | 1983 | J. Dermatol. | pmid:6321577 |
| Bassett JM et al. | Regulation of insulin secretion in the ovine foetus in utero. Effects of sodium valerate on secretion and of adrenocorticotrophin-induced premature parturition on the insulin secretory response to glucose. | 1973 | J. Endocrinol. | pmid:4345761 |
| Dafopoulos K et al. | The effect of estrogens on plasma ghrelin concentrations in women. | 2010 | J. Endocrinol. Invest. | pmid:20348837 |
| Punnonen R et al. | Demonstration of estrogen receptors in the skin. | 1980 Jul-Sep | J. Endocrinol. Invest. | pmid:7430556 |
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| Zanor MI et al. | Metabolic characterization of loci affecting sensory attributes in tomato allows an assessment of the influence of the levels of primary metabolites and volatile organic contents. | 2009 | J. Exp. Bot. | pmid:19346240 |
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| Sentürk E et al. | Treatment efficiency and VFA composition of a thermophilic anaerobic contact reactor treating food industry wastewater. | 2010 | J. Hazard. Mater. | pmid:20022175 |
| Saha SP et al. | Incorporation of polyethylene glycol in polyhydroxyalkanoic acids accumulated by Azotobacter chroococcum MAL-201. | 2006 | J. Ind. Microbiol. Biotechnol. | pmid:16550437 |
| Khanna S and Srivastava AK | Production of poly(3-hydroxybutyric-co-3-hydroxyvaleric acid) having a high hydroxyvalerate content with valeric acid feeding. | 2007 | J. Ind. Microbiol. Biotechnol. | pmid:17268758 |
| Song R et al. | Synthesis and cytotoxicity of new platinum(IV) complexes of mixed carboxylates. | 2003 | J. Inorg. Biochem. | pmid:12888269 |
| Hölzle E and Plewig G | Effects of dermatitis, stripping, and steroids on the morphology of corneocytes. A new bioassay. | 1977 | J. Invest. Dermatol. | pmid:864272 |
| Pinto O et al. | Synthesis of tetrahydronaphthalene lignan esters by intramolecular cyclization of ethyl p-azidophenyl-2-phenylalkanoates and evaluation of the growth inhibition of human tumor cell lines. | 2011 | J. Med. Chem. | pmid:21504224 |
| Tomiyama T et al. | Synthesis and biological activity of novel carbacyclins having bicyclic substituents on the omega-chain. | 1989 | J. Med. Chem. | pmid:2666669 |
| Jiracek J et al. | S-alkylated homocysteine derivatives: new inhibitors of human betaine-homocysteine S-methyltransferase. | 2006 | J. Med. Chem. | pmid:16789755 |
| Bourel-Bonnet L et al. | Solid-phase total synthesis of kahalalide A and related analogues. | 2005 | J. Med. Chem. | pmid:15743176 |
| Potu RB et al. | The effect of lipid supplements on ruminal bacteria in continuous culture fermenters varies with the fatty acid composition. | 2011 | J. Microbiol. | pmid:21538241 |
| Brady GP and Sharp KA | Decomposition of interaction free energies in proteins and other complex systems. | 1995 | J. Mol. Biol. | pmid:7473761 |
| Merrouche R et al. | Dithiolopyrrolone antibiotic formation induced by adding valeric acid to the culture broth of Saccharothrix algeriensis. | 2010 | J. Nat. Prod. | pmid:20507156 |