Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Uterine Hemorrhage | D014592 | 6 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Perlman BJ and Goldstein DB | Membrane-disordering potency and anticonvulsant action of valproic acid and other short-chain fatty acids. | 1984 | Mol. Pharmacol. | pmid:6431262 |
| Bui CT et al. | Comparative study of reductive amination reaction on 5-(4-formyl-3,5-dimethoxyphenoxy)valeric acid and its monomethoxy analog using the Multipin approach. | 1998 | Mol. Divers. | pmid:10729900 |
| Perroud B et al. | Pathway analysis of kidney cancer using proteomics and metabolic profiling. | 2006 | Mol. Cancer | pmid:17123452 |
| Yoneda S et al. | Effects of short-chain fatty acids on Actinomyces naeslundii biofilm formation. | 2013 | Mol Oral Microbiol | pmid:23731652 |
| Connor SC et al. | Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes. | 2010 | Mol Biosyst | pmid:20567778 |
| Kilner J et al. | A proteomic analysis of differential cellular responses to the short-chain fatty acids butyrate, valerate and propionate in colon epithelial cancer cells. | 2012 | Mol Biosyst | pmid:22075547 |
| ORIA M | [Not Available]. | 1947 | Minerva Med. | pmid:20254142 |
| Trotsenko IuA and Belova LL | [Organization and regulation of polyhydroxybutyrate/valerate biosynthesis in bacteria]. | 2000 Nov-Dec | Mikrobiologiia | pmid:11195572 |
| Wallace RJ et al. | Metabolic properties of Eubacterium pyruvativorans, a ruminal 'hyper-ammonia-producing' anaerobe with metabolic properties analogous to those of Clostridium kluyveri. | 2004 | Microbiology (Reading, Engl.) | pmid:15347751 |
| Charrier C et al. | A novel class of CoA-transferase involved in short-chain fatty acid metabolism in butyrate-producing human colonic bacteria. | 2006 | Microbiology (Reading, Engl.) | pmid:16385128 |